An emulsification device disclosed herein comprises: an outer tank having a first pressing end and a first exit end; and an inner tank having a second pressing end and a second exit end, wherein the inner tank is disposed inside the outer tank and the second exit end is located closer than the second pressing end to the first exit end, the outer tank is configured to house a first liquid and the inner tank is configured to house a second liquid, the first and second pressing ends are arranged so that one pressure can be applied onto both the first and second liquids, and under the pressure, the second liquid flows out of the inner tank through the second exit end and contacts with the first liquid in the outer tank so that an emulsion droplet comprising the second liquid within the first liquid is formed.

There is provided an arrangement (100) which allows for mixing a first fluid with a second fluid at a predetermined volume mixing ratio in a capillary driven fluidic system. The arrangement (100) allows filling an initially empty mixing chamber (110) with the first fluid. The arrangement then allows emptying a predetermined fraction of the first fluid from the mixing chamber (110) such as to form an empty space in the mixing chamber (110). The arrangement then allows filling the empty space of the mixing chamber (110) with the second fluid, thereby allowing a predetermined volume of the first fluid to mix with a predetermined volume of the second fluid over time.

An apparatus, vortex generator assembly and method for automated cell lysis and nucleic acid purification and processing. The vortex generator assembly includes sample holder having a lysis well, at least one wash well, and an elution well. The vortex generator assembly also includes a sample holder cover having a plurality of vibration rods for creating a vortex in the wells of the sample holder. The apparatus includes motor operating a rotating cam to cause the vibration rods to vibrate and create the vortex in a well holding fluid and magnetic beads, wherein the vortexing speed is sufficient to overcome the magnetic attraction between the beads and disperse the beads in solution, to collect nucleic acids such as DNA.

The invention discloses a low-energy consumption solvent dilution device for pre-treating samples comprising an accommodating unit, the accommodating unit including a case and an accommodating portion arranged inside the case; an input unit, which including an inlet, a second outlet and a third outlet extending into the case; a cleaning unit, which including a receiving assembly arranged below the second outlet and the third outlet, and a conveying assembly communicated with a receiving assembly. The input unit including a first tube connecting with the inlet, and a second tube and a third tube extending out of the second outlet and the third outlet, respectively.

The present invention completes dispensing and diluting the sample fixative in the box, the dispersion of the fixative is reduced. Avoid unnecessary contact for operators. It improves the safety and accuracy of the experiment, and significantly reduces energy consumption and labor costs.

Method of analysis. In the method, a first emulsion and a second emulsion substantially separated from one another by a spacer fluid may be formed. The first emulsion, the spacer fluid, and the second emulsion may be flowed in a channel from a fluid inlet to a fluid outlet of a heating and cooling station having two or more temperature-controlled zones, such that each emulsion is thermally cycled to promote amplification of a nucleic acid target in droplets of the emulsion. Amplification data may be collected from individual droplets of each emulsion downstream of the heating and cooling station. A level of the nucleic acid target present in each emulsion may be determined based on the amplification data collected from the individual droplets of the emulsion.

A liquid dispensing pump (10) comprises: a first liquid storage cylinder (11), a second liquid storage cylinder (12), a first plunger (13) movably connected to the first liquid storage cylinder (11), a second plunger (14) movably connected to the second liquid storage cylinder (12), and a drive assembly (15) connected to the first plunger (13) and the second plunger (14). The first liquid storage cylinder (11) is provided with a first liquid entry and exit port (111). The second liquid storage cylinder (12) is provided with a second liquid entry and exit port (121). One end of the first plunger (13) is inserted into an internal cavity of the first liquid storage cylinder (11). One end of the second plunger (14) is inserted into an internal cavity of the second liquid storage cylinder (12). Further provided is a liquid dispensing device (100). The advantageous effect of the invention is: during each linear reciprocating movement cycle of the first plunger (13) and the second plunger (14), the first liquid storage cylinder (11) and the second liquid storage cylinder (12) discharge corresponding ingredients according to a pre-determined mixing ratio, and a mixed solution according to the pre-determined mixing ratio is obtained, thereby achieving precise mixing of different ingredients. In addition, the dispensing pump (10) discharges ingredients at a consistent ratio, thereby achieving uniform mixing without a dedicated mixer.

The present invention discloses an electrophoretic chip comprising: (a) a non-conductive substrate designed to support elements of said electrophoretic chip; (b) an electrode structure for conducting current through said electrophoretic chip, printed on said non-conductive substrate and comprising a counter electrode and at least one working electrode, each electrode comprising a conductive low-resistance ink layer printed on the non-conductive substrate, and a carbon ink layer printed on top of and fully or partially covering said conductive low-resistance ink layer; (c) a dielectric ink insulator layer placed on top of, and covering, said electrode structure, said dielectric ink insulator layer having at least one opening above the counter electrode and at least one opening above said at least one working electrode, thereby forming at least one addressable location; and (d) a molecule capturing matrix spotted on and covering said at least one addressable location, thereby creating at least one microgel region.

There is provided a method of extracting material from a fluid method of extracting material from a fluid, the fluid being held within a fluid chamber. The method comprises drawing, with a magnetic field generating system, at least one magnetically susceptible member through the fluid around a closed path between at least three points in the chamber, said at least one member being adapted to bind to material in fluid in the chamber. The at least three points are arranged relative to each other in a shape having at least two dimensions, the magnetic field generating system being configured to move the at least on magnetically susceptible member directly between the at least three points, material in the fluid binding to the at least one magnetically susceptible member when it comes into contact with the at least one member as it moves through the fluid.

The present invention relates to a mixing assembly for mixing a fluid, wherein the mixing assembly comprises a fluid accommodation portion configured to accommodate the fluid, and a wave source, wherein the wave source is configured to generate an acoustic wave. The mixing assembly is configured to inject at least part of the acoustic wave into the fluid accommodated in the fluid accommodation portion to thereby cause mixing of the fluid in the fluid accommodation portion. The present invention also relates to a corresponding liquid chromatography system, method and use.

The present invention generally relates to droplet libraries and to systems and methods for the formation of libraries of droplets. The present invention also relates to methods utilizing these droplet libraries in various biological, chemical, or diagnostic assays.