Disclosed is a device for contactlessly mixing fluid present on the upper surface of the slide, where the device comprises a first nozzle array and a second nozzle array, the first nozzle array adapted to impart a bulk fluid flow to the fluid present on the upper surface of the slide, and the second nozzle array adapted to impart at least a first regional fluid flow to at least a portion of the fluid present on the upper surface of the slide

The invention discloses a method for predicting the pH error during mixing of an aqueous buffer comprising at least one weak acid species and/or at least one weak base species, which comprises the steps of: a) selecting a start composition of the buffer, giving start values for pH and/or buffer concentration; b) calculating the concentrations of all ionic species present in the buffer at a specified pH value from the total composition of the buffer and available dissociation constants; c) calculating the contribution of each of said ionic species to a total pH variance from the specified pH value, the buffer concentration, the calculated concentrations of the ionic species and variances in amounts of buffer components; d) calculating the pH variance, and; e) setting the variance or the square root of the pH variance as the pH error.

A method of processing a sample in a receptacle comprising a plurality of chambers. Each of the chambers is connected to at least one other chamber by a portal and at least a first one of the chambers is formed of a flexible material. The method includes the steps of causing gas bubbles contained in the first chamber to accumulate in a portion of the first chamber, applying a compressive external force to the first chamber to cause some or all of the liquid contents of the first chamber to flow into an interconnected second chamber through a portal connecting the first and second chambers; and preventing the gas bubbles accumulated in a portion of the first chamber from flowing through the portal into the second chamber.

A fluid mixing device is provided with a plurality of flow channel units disposed to be divided in a plurality of layers. Each of the flow channel units has an inflow port, an outflow port, and a plurality of branch flow channels making the inflow port and the outflow port communicate with each other. The flow channel units located in different layers are connected to each other at the inflow port and the outflow port between the flow channel units, thereby configuring a three-dimensional flow channel as a whole. When the direction from the inflow port to the outflow path of each flow channel unit is set to be a flow direction in the flow channel unit, the flow directions intersect each other between the respective layers.

A mixing bag for use in bioprocessing in which a fluid is received and agitated using an internal fluid-agitating element driven by an external motive device is disclosed. The bag may include an integral sparger and sensor receiver. Related methods are also disclosed.

The invention relates to an arrangement (10) for preparing a plurality of samples for an analytical method, comprising a carousel (14) with a solid housing (12) and moveable receiving parts (16) for the sample containers (18); a control for controlling the receiving parts (16) in the carousel (14); and a sample receiving device (24) for providing the sample to be analysed; one or more stations (24, 26, 28, 30, 32) for preparing samples are provided on the carousel (14), the receiving parts (16) for the sample containers (18) of the carousel (14) can be positioned on said stations; a centrifuge (22) with pairs of opposite lying receiving parts (42) provided for the sample containers (18), and said receiving parts (42) are arranged such that they can move on the centrifuge (22) and the movements can be controlled in such a manner that the sample holder (18) can be transferred between a receiving part (16) in the carousel (14) and a receiving part (42) in the centrifuge (22).

An apparatus for generating one or several droplets of a first liquid in a second liquid immiscible with the first liquid includes a rotational body and a drive apparatus. The rotational body includes a fluid chamber, a fluid channel and a transition area. The transition area includes a first expansion area and a second expansion area. The drive apparatus is configured to provide the rotational body with such a rotation that the first liquid is supplied centrifugally to the fluid chamber and that centrifugally hydrodynamically induced pressure and lifting forces are caused due to the second expansion area, which cause a droplet break-off in the first liquid, such that a droplet of the first liquid embedded in the second liquid is generated.

A unit for grinding biological samples, comprising a grinding device including at least two tubes having different volumes, suitable for being mounted on a support of the grinding device, each tube comprising an inner space having a height (h) along the axis of the corresponding tube, and being intended to contain samples to be ground, means for driving the support in a precession movement, the support having an axis the position of which varies by describing a cone, each tube being subjected to a movement (d) defined by the projection, onto the axis of said cone, of the distance between the extreme positions of a same point of the tube during the precession movement.

Disclosed is a test device and a method for qualitatively and/or quantitatively measuring the concentration of an analyte in a biological fluid sample. The test device includes a housing defining a sample port, a test well containing a stirrer and a conjugate, and a test strip disposed within the housing. The test well is also defined by being located between the sample port and the test strip. Fluid flows from the test well onto the test strip, which has a trapping zone which binds the analyte and allows for its detection. A control zone may also be included. The test device is generally adapted to use a sandwich assay. Also disclosed is a system comprising the test device and a signal sensing device; and a method for using the test device.

Provided herein are methods and systems of the invention that include the use of an automated solution dispenser to form a solution according to at least one target characteristic. A controller may be operatively connected to the automated solution dispenser, wherein the controller is programmed to direct mixing of one or more solids and one or more liquids to produce the solution. At least a portion of the solution can be dispensed into one or more containers.