The present invention provides a new chemical process, a new cassette configuration, and new software for the automated production of multiple batches of an [.sup.18F]labelled compound on a single cassette. The invention allows one synthesizer in one hot cell to produce sequentially a plurality of batches of [.sup.18F]-labelled PET tracer in the same day. In particular, the present invention provides a novel arrangement useful for the trapping of [.sup.18F]fluoride and recovery of [.sup.18O]water.

The present invention provides a new chemical process, a new cassette configuration, and new software for the automated production of multiple batches of an [.sup.18F]labelled compound on a single cassette. The invention allows one synthesizer in one hot cell to produce sequentially a plurality of batches of [.sup.18F]-labelled PET tracer in the same day. In particular, the present invention provides a novel arrangement useful for the trapping of [.sup.18F]fluoride and recovery of [.sup.18O]water.

To provide a porous silica having high alkali resistance; and a chromatographic carrier using such a porous silica. A porous silica comprising a phosphorus oxide component and a zirconium oxide component, wherein the amount of phosphorus atoms per unit specific surface area of the porous silica is from 1 μmol/m.sup.2 to 25 μmol/m.sup.2; and the amount of zirconium atoms per unit specific surface area of the porous silica is from 1 μmol/m.sup.2 to 15 μmol/m.sup.2. And, a chromatographic carrier which contains a ligand immobilized to such a porous silica.

The present disclosure relates to a method for regeneration of spent ion exchange resins to obtain regenerated ion-exchange resins. The regenerated ion exchange resins can efficiently reduce the total acid number (TAN) of highly acidic crude oils. The present disclosure particularly relates to a method of treatment of spent ion exchange resins using at least one non-acidic crude oil condensate and at least one polar organic solvent.

The present disclosure relates to a method for regeneration of spent ion exchange resins to obtain regenerated ion-exchange resins. The regenerated ion exchange resins can efficiently reduce the total acid number (TAN) of highly acidic crude oils. The present disclosure particularly relates to a method of treatment of spent ion exchange resins using at least one non-acidic crude oil condensate and at least one polar organic solvent.

A hyper-productive chromatography technique includes providing a scalable and stackable chromatographic cassette, loading a sample to be processed, operating the scalable chromatographic cassette having an adsorptive chromatographic bed having a volume greater than 0.5 liter by establishing a flow at a linear velocity greater than 500 cm/hr with a residence time of the loading step of less than one minute.

The invention is directed to methods for purifying recombinant proteins, e.g. HIV-1 envelope trimers and/or nanoparticles, wherein the methods do not use an affinity step.

The invention is directed to methods for purifying recombinant proteins, e.g. HIV-1 envelope trimers and/or nanoparticles, wherein the methods do not use an affinity step.

A method for preparing needle coke for ultra-high power (UHP) electrodes from heavy oil is provided. In this method, heavy oil is used as a raw material. The size exclusion chromatography (SEC) is conducted with polystyrene (PS) as a packing material to separate out specific components with a relative molecular weight of 400 to 1,000. The ion-exchange chromatography (IEC) is conducted to remove acidic and alkaline components to obtain a neutral raw material. The neutral raw material is subjected to two-stage consecutive carbonization to obtain green coke, and the green coke is subjected to high-temperature calcination to obtain the needle coke for UHP electrodes. The needle coke has a true density of more than 2.13 g/cm.sup.3 and a coefficient of thermal expansion (CTE) of ≤1.15×10.sup.−6/° C. at 25° C. to 600° C.

A method for preparing needle coke for ultra-high power (UHP) electrodes from heavy oil is provided. In this method, heavy oil is used as a raw material. The size exclusion chromatography (SEC) is conducted with polystyrene (PS) as a packing material to separate out specific components with a relative molecular weight of 400 to 1,000. The ion-exchange chromatography (IEC) is conducted to remove acidic and alkaline components to obtain a neutral raw material. The neutral raw material is subjected to two-stage consecutive carbonization to obtain green coke, and the green coke is subjected to high-temperature calcination to obtain the needle coke for UHP electrodes. The needle coke has a true density of more than 2.13 g/cm.sup.3 and a coefficient of thermal expansion (CTE) of ≤1.15×10.sup.−6/° C. at 25° C. to 600° C.