In one embodiment, the present application discloses mixtures comprising (a) water in an amount of at least 1% wt/wt of the mixture; (b) a transition metal catalyst; and (c) one or more solubilizing agents; and methods for using such mixtures for performing transition metal mediated bond formation reactions.

In one embodiment, the present application discloses mixtures comprising (a) water in an amount of at least 1% wt/wt of the mixture; (b) a transition metal catalyst; and (c) one or more solubilizing agents; and methods for using such mixtures for performing transition metal mediated bond formation reactions.

Provided is a method for continuously producing a cyclic carbonate, by which generation of a glycol in a reaction for synthesizing a cyclic carbonate is suppressed, and a cyclic carbonate having a high purity can be efficiently obtained even by simple purification. A method for continuously producing a cyclic carbonate, including filling a catalyst in a fixed-bed tube reactor, and continuously feeding carbon dioxide and an epoxide to the fixed-bed tube reactor to thereby bringing the carbon dioxide and the epoxide into contact with the catalyst, while continuously withdrawing the reaction liquid in the fixed-bed tube reactor, wherein the method includes a pre-treatment step in which a pre-treatment liquid containing a cyclic carbonate is brought into contact with the catalyst before feeding the carbon dioxide and the epoxide to the fixed-bed tube reactor, and the generated glycol is removed out of the system.

A process for producing a supported single-site catalyst is provided. The process comprises forming a slurry comprising a dried inorganic oxide support, an organic solvent, and an aluminoxane activator; maintaining the temperature of the slurry from about 100 C. to about 200 C. for a time period from about 0.5 to about 10 hours to form a supported aluminoxane slurry; and contacting N the supported aluminoxane slurry with a single-site catalyst component to form a supported single-site catalyst. The organic solvent comprises one or more non-aromatic organic compounds having a boiling point of about 100 C. or greater in an amount of about 50 CA wt. % or greater with respect to the total amount of the organic solvent.