The present invention involves a fill needle system for aseptically dispensing a pharmaceutical fluid in an aseptic chamber comprises a fill needle tubing in fluid communication with a pharmaceutical fluid source via flexible tubing and extending through a fill needle hub; a fill needle dispensing tip disposed at a dispensing end of the fill needle tubing; a fill needle sheath shaped and arranged to removably mate with and seal aseptically to the fill needle hub to form an aseptically sealed volume enclosing the dispensing tip; and a fluid pressure pulse induction system disposed and configured to compress the flexible tubing in order to dislodge droplets of pharmaceutical fluid retained on the dispensing tip after halting dispensing of the pharmaceutical fluid. An associated method of dispensing pharmaceutical fluid comprises operating the fluid pressure pulse induction system to dislodge the droplets. The system may comprise a controller for automatically controlling the dispensing and droplet dislodging.

A beta container for an alpha-beta port system includes a sheath for receiving transport material and a flange part having a through opening for transferring the transport material from and/or into the sheath, a first interface for a reversible connection to an alpha connection of the port system, and a second interface for releasable attachment of a beta cover for closing the through opening. An edge of the sheath is connected with a first surface of a ring which encompasses a jacket surface of the flange part, the first surface and the jacket surface having different materials. An elastic bellows may be fastened to the flange part such that, in the relaxed state, it engages over the second interface and/or projects out of the through-opening on the side facing away from the sheath, and such that it can be compressed. At least one transponder for transmitting an identification may be arranged on the flange part.

An integrated and modular air and lighting plenum that is the primary directional lighting mounting apparatus and laminar flow diffuser of an HVAC system in a healthcare setting. The plenum provides laminar air flow from the ceiling to the room in which it is located in accordance with HVAC requirements for healthcare environment settings, by using a plurality of cylindrical airflow outlets. The use of cylindrical airflow outlets promotes laminar airflow by reducing sharp boundaries that induce turbulence (e.g., the corners of rectangular or square outlets) and creates a highly sterile environment around the patient and staff in the operating room. The surgical lights used in the integrated air and lighting plenum allow the beam direction, spot size, focal point, brightness, and color temperature of the emitted light to be controlled.

An integrated and modular air and lighting plenum that is the primary directional lighting mounting apparatus and laminar flow diffuser of an HVAC system in a healthcare setting. The plenum provides laminar air flow from the ceiling to the room in which it is located in accordance with HVAC requirements for healthcare environment settings, by using a plurality of cylindrical airflow outlets. The use of cylindrical airflow outlets promotes laminar airflow by reducing sharp boundaries that induce turbulence (e.g., the corners of rectangular or square outlets) and creates a highly sterile environment around the patient and staff in the operating room. The surgical lights used in the integrated air and lighting plenum allow the beam direction, spot size, focal point, brightness, and color temperature of the emitted light to be controlled.

An apparatus for a sterile transfer of a material incudes a second safety device which locks an actuation mechanism in a closed position and unlocks the actuation mechanism when a container flange is correctly connected to a port flange, a third safety device which locks the container flange connected to the port flange when the actuation mechanism leaves the closed position, and a fourth safety device which blocks a return of the actuation mechanism from the open position to the closed position when the port door is open. The second, third and/or fourth safety device comprises two magnetic elements with at least one closed wall being arranged between the two magnetic elements. The two magnetic elements are configured to mutually attract or to mutually repel through the at least one closed wall either in a lock position or in an unlock position of the second, third and/or fourth safety device.

An apparatus for a sterile transfer of a material incudes a second safety device which locks an actuation mechanism in a closed position and unlocks the actuation mechanism when a container flange is correctly connected to a port flange, a third safety device which locks the container flange connected to the port flange when the actuation mechanism leaves the closed position, and a fourth safety device which blocks a return of the actuation mechanism from the open position to the closed position when the port door is open. The second, third and/or fourth safety device comprises two magnetic elements with at least one closed wall being arranged between the two magnetic elements. The two magnetic elements are configured to mutually attract or to mutually repel through the at least one closed wall either in a lock position or in an unlock position of the second, third and/or fourth safety device.

A method and a device connects a partially flexible protective cover (2) sealed against the environment and forming a barrier between a contaminated area (12) and an uncontaminated area, to a partially flexible safety cover (20) by transferring the protective cover (2) out of the contaminated area (12) inverting the protective cover (2) over an opening such that its inside is turned out and then severing it from the safety cover (20) and closing the opening; or transferring the protective cover (2) from the contaminated area (12) by sheathing the protective cover (2) with the safety cover (20) as it is pulled through a passage and subsequently severing of both covers (2, 20) from the safety cover (20) and closing the sheathing; or pulling the protective cover (2) back into the contaminated area (12) and then sealing the ends shut to sever the safety cover (20) by forming a further sealed joint between adjacent film parts.

A method and a device connects a partially flexible protective cover (2) sealed against the environment and forming a barrier between a contaminated area (12) and an uncontaminated area, to a partially flexible safety cover (20) by transferring the protective cover (2) out of the contaminated area (12) inverting the protective cover (2) over an opening such that its inside is turned out and then severing it from the safety cover (20) and closing the opening; or transferring the protective cover (2) from the contaminated area (12) by sheathing the protective cover (2) with the safety cover (20) as it is pulled through a passage and subsequently severing of both covers (2, 20) from the safety cover (20) and closing the sheathing; or pulling the protective cover (2) back into the contaminated area (12) and then sealing the ends shut to sever the safety cover (20) by forming a further sealed joint between adjacent film parts.

A disposable isolator including a bottom, a flexible peripheral wall defining a clean and sterile inner volume, a first pair of joining parts forming a first tight junction at the bottom, this first pair including an inner part placed inside the inner volume and suitable for positioning containers, and an outer part placed outside the inner volume and suitable for cooperating by shape matching with a positioning cavity provided on a support table, and a second pair of joining parts forming a second tight junction at the peripheral wall and including an outer part suitable for being connected to a robot, and an inner part suitable for being connected to a manipulating tool, the first and second pairs being designed so that the robot applies the manipulating tool on the containers positioned on the support table.

A disposable isolator including a bottom, a flexible peripheral wall defining a clean and sterile inner volume, a first pair of joining parts forming a first tight junction at the bottom, this first pair including an inner part placed inside the inner volume and suitable for positioning containers, and an outer part placed outside the inner volume and suitable for cooperating by shape matching with a positioning cavity provided on a support table, and a second pair of joining parts forming a second tight junction at the peripheral wall and including an outer part suitable for being connected to a robot, and an inner part suitable for being connected to a manipulating tool, the first and second pairs being designed so that the robot applies the manipulating tool on the containers positioned on the support table.