A safety cabinet includes an operation stage on which an operation is performed, an operation space in which an operator performs the operation, a front panel disposed in front of the operation space, an operation opening connected to the operation space, exhausting means that suctions air from the operation opening and exhausts air in the operation space outside the safety cabinet through air purifying means, and visualizing means that visualizes an air flow in the operation space.

1. Method and device for connecting a protective cover to a safety cover sealed against the environment.

2. The invention relates to a method and an assigned device for connecting a first at least partially flexible protective cover (2) sealed against the environment, which cover forms a barrier between a contaminated (12) and an uncontaminated area, to a second at least partially flexible safety cover (20) including the process stages listed below: Transferring the protective cover (2) out of the contaminated area (12) by inverting the protective cover (2) over an opening such that its inside is turned out and then severing it from the safety cover (20) and closing the opening; or transferring the protective cover (2) from the contaminated area (12) by sheathing the protective cover (2) with the safety cover (20) as it is pulled through a passage and subsequent severing of both covers (2, 20) from the safety cover (20) and closing the sheathing; or pulling the protective cover (2) back into the contaminated area (12) and then sealing the ends shut to sever the safety cover(20) by forming a further sealed joint between adjacent film parts.

1. Method and device for connecting a protective cover to a safety cover sealed against the environment.

2. The invention relates to a method and an assigned device for connecting a first at least partially flexible protective cover (2) sealed against the environment, which cover forms a barrier between a contaminated (12) and an uncontaminated area, to a second at least partially flexible safety cover (20) including the process stages listed below: Transferring the protective cover (2) out of the contaminated area (12) by inverting the protective cover (2) over an opening such that its inside is turned out and then severing it from the safety cover (20) and closing the opening; or transferring the protective cover (2) from the contaminated area (12) by sheathing the protective cover (2) with the safety cover (20) as it is pulled through a passage and subsequent severing of both covers (2, 20) from the safety cover (20) and closing the sheathing; or pulling the protective cover (2) back into the contaminated area (12) and then sealing the ends shut to sever the safety cover(20) by forming a further sealed joint between adjacent film parts.

An anaerobic chamber system to evaluate human enteric disease is described herein that can be used to test therapeutic components. In specific embodiments, the anaerobic chamber is used to determine the effect of one or more bacterial communities on ex vivo enteroid cultures. In one application, the anaerobic chamber system is used to determine the efficacy of therapeutic components in ameliorating human enteric disease using personalized medicine.

A method for conditioning air in a test space of a test chamber which receives test material. A temperature in a range of 20 C. to +180 C. is established within the test space with a cooling device. The cooling device includes a cooling circuit with a refrigerant, a heat exchanger, a compressor, a condenser and an expansion element. An internal heat exchanger of the cooling circuit is connected to a high-pressure side of the cooling circuit upstream of the expansion element and downstream of the condenser and to a low-pressure side of the cooling circuit upstream of the compressor and downstream of the heat exchanger and is used to cool the refrigerant of the high-pressure side. A zeotropic refrigerant is used and the internal heat exchanger is used to cool the refrigerant of the high-pressure side to lower an evaporation temperature at the expansion element.

A method is described for providing selective communication between two enclosures. The first enclosure includes a first flange and a first door. The second enclosure includes a second flange and a second door. The method includes performing sequentially the steps of arranging the second flange on the first flange, axially maintaining the second flange on the first flange by snap-fitting, securing the first flange to the second flange, securing the first door to the second door, releasing the first door from the first flange, releasing the second door from the second flange, opening the first door relative to the first flange, closing the first door relative to the first flange, securing the first door to the first flange and securing the second door to the second flange, unlocking the first door from the second door, and separating the first door from the second door.

A method is described for providing selective communication between two enclosures. The first enclosure includes a first flange and a first door. The second enclosure includes a second flange and a second door. The method includes performing sequentially the steps of arranging the second flange on the first flange, axially maintaining the second flange on the first flange by snap-fitting, securing the first flange to the second flange, securing the first door to the second door, releasing the first door from the first flange, releasing the second door from the second flange, opening the first door relative to the first flange, closing the first door relative to the first flange, securing the first door to the first flange and securing the second door to the second flange, unlocking the first door from the second door, and separating the first door from the second door.

A tight connection device for the aseptic transfer of a biopharmaceutical product includes: a stationary temporary clamping means keeping the container hermetically clamped against the chamber; a stationary unlocking means capable of switching the container from an initial locked position to an intermediate unlocked position; a stationary locking means; and an annular functional crown capable of being rotated to actuate the stationary unlocking means and the stationary locking means of the container. The stationary unlocking means and the stationary locking means are mechanically linked to the annular functional crown and arranged such that the rotation of the annular functional crown and the end locked position. The device further includes stationary immobilising/release means capable of allowing and preventing the annular functional crown to rotate.

A tight connection device for the aseptic transfer of a biopharmaceutical product includes: a stationary temporary clamping means keeping the container hermetically clamped against the chamber; a stationary unlocking means capable of switching the container from an initial locked position to an intermediate unlocked position; a stationary locking means; and an annular functional crown capable of being rotated to actuate the stationary unlocking means and the stationary locking means of the container. The stationary unlocking means and the stationary locking means are mechanically linked to the annular functional crown and arranged such that the rotation of the annular functional crown and the end locked position. The device further includes stationary immobilising/release means capable of allowing and preventing the annular functional crown to rotate.

A rail clamp comprising two clamp elements (30a, 30b) securable together in clamping arrangement about a railway rail, wherein at least one of the clamp elements (30a, 30b) can include sensor retaining means to hold a sensor to make measurements relating to the rail. A first of said two clamp elements (30b) has a clamp head to engage a fish plate (14b) or a web-side of a railway rail. A clamp foot (34b) engages the underside of a railway rail foot (13). A second of said two clamp elements (30a) having a clamp head to engage the opposite fish plate or web-side of a railway rail and a clamp foot (34a) to engage the underside of the clamp foot (34b) of the first clamp element (34b). The first and second clamp elements (30a, 30b) are secured together by a connector (35), optionally a bolt, to a railway rail.