B01L1/02

GENERATING DEVICE OF SIMULATING PARTICULATE ENVIRONMENT FOR EXPERIMENTAL ANIMAL

A generating device of simulating a particulate environment for an experimental animal includes an experimental chamber. An ultrasonic atomization device is installed at the bottom adjacent to the center of the experimental chamber. The upper side of the ultrasonic atomization device is connected to a guide device for guiding particles. The guide device includes an air seal cover, and a micro fan is installed inside the air seal cover to drive the movement of particles generated in the ultrasonic atomization device. Air guide pipes are fixedly connected to a side wall of the air seal cover. The generating device has good sealing performance, and can generate a variety of particle simulation environments to accurately and effectively simulate the biological effect of particles in the animal body. The generating device can improve the particle simulation environment, reduce the deviation of experimental data, and ensure the accuracy of the overall experimental data.

SYSTEMS AND METHODS FOR LOADING REAGENT-CONTAINING MICROFLUIDIC CHIPS

A microfluidic device can include a microfluidic circuit that comprises an inlet port, a reagent-containing chamber configured to receive fluid from the inlet port, a non-aqueous-liquid-containing reservoir configured to receive liquid from the chamber, and a droplet-generating region configured to receive and produce droplets of liquid from the reservoir. The circuit can also include first and second valves or frangible members. The first valve or frangible member can have closed position in which fluid is prevented from entering or exiting the chamber therethrough and an open position in which fluid is permitted to enter or exit the chamber therethrough. The second valve or frangible member can have a closed position in which fluid is prevented from flowing between the chamber and the reservoir therethrough and an open position in which fluid is permitted to flow between the chamber and the reservoir therethrough.

PRODUCTION DEVICE, IN PARTICULAR FOR THE PHARMACEUTICAL INDUSTRY

A production device including an isolator housing to receive functional components of the production device and products in an interior of the production device and to hermetically seal the components from the surroundings. The production device includes at least one robot received in the isolator housing, wherein the robot is one or more of operable to carry out specific tasks or operable to be remotely controllable by means of a remote controller. The production device includes at least one linear movement unit received in the isolator housing and configured to move the at least one robot long a linear movement axis. The production device includes at least one control unit to control one or more of a movement or an operation of the at least one robot.

GLOVE ARRANGEMENT FOR A BARRIER SYSTEM
20220331996 · 2022-10-20 ·

The present disclosure relates to a glove arrangement (20) for mounting to a barrier wall (15) of a barrier system (10) comprising a sleeve arrangement (21). The first and second sleeves (40, 41) comprise first and second internal surfaces (90, 91). The intermediate sleeve (40) comprises an intermediate internal surface (92), an outer perimeter (61) attached to the first sleeve (40) and an inner perimeter (62) attached to the second sleeve (41), the outer perimeter (61) having a greater diameter than the inner perimeter (62). In an extended configuration the first sleeve (40) extends from the second and intermediate sleeves (40) for use during manipulation of the glove (22) by an operator. In a retracted configuration the second sleeve (41) is retracted at least partially inside the first sleeve (40) about the intermediate sleeve (40) such that the first and second internal surfaces (90, 91) at least partially face each other. The intermediate sleeve (40) separates the intermediate internal surface (92) from itself and from the first and second internal surfaces (90, 91) to form a cavity (48) between the first, second and intermediate internal surfaces (90, 91, 92).

GLOVE ARRANGEMENT FOR A BARRIER SYSTEM
20220331996 · 2022-10-20 ·

The present disclosure relates to a glove arrangement (20) for mounting to a barrier wall (15) of a barrier system (10) comprising a sleeve arrangement (21). The first and second sleeves (40, 41) comprise first and second internal surfaces (90, 91). The intermediate sleeve (40) comprises an intermediate internal surface (92), an outer perimeter (61) attached to the first sleeve (40) and an inner perimeter (62) attached to the second sleeve (41), the outer perimeter (61) having a greater diameter than the inner perimeter (62). In an extended configuration the first sleeve (40) extends from the second and intermediate sleeves (40) for use during manipulation of the glove (22) by an operator. In a retracted configuration the second sleeve (41) is retracted at least partially inside the first sleeve (40) about the intermediate sleeve (40) such that the first and second internal surfaces (90, 91) at least partially face each other. The intermediate sleeve (40) separates the intermediate internal surface (92) from itself and from the first and second internal surfaces (90, 91) to form a cavity (48) between the first, second and intermediate internal surfaces (90, 91, 92).

Benchtop incubator
11471891 · 2022-10-18 · ·

A bench top incubator is described. The bench top incubator includes a first tray stack designed to retain microscope slides in a plurality of slide trays and a second tray stack designed to retain multi-well plates in a plurality of plate trays. The incubator is relatively simple and small in design and can be conveniently located to carry out temperature processing of biological samples such as fixed cells and tissues, biological fluids, and so forth.

Cell sorter in a sealed system under controlled atmosphere

The present invention relates generally to an apparatus that is able to provide a sealed chamber system including a cell sorter, that allows for various oxygen tensions of choice to be maintained during cell harvest, sorting (and isolation of sub-populations of cells), analysis, etc.

Cell sorter in a sealed system under controlled atmosphere

The present invention relates generally to an apparatus that is able to provide a sealed chamber system including a cell sorter, that allows for various oxygen tensions of choice to be maintained during cell harvest, sorting (and isolation of sub-populations of cells), analysis, etc.

METHODS AND APPARATUS FOR A COOLED CHEMICAL CABINET
20230107558 · 2023-04-06 ·

Methods and apparatus for a cooled chemical cabinet include a cooling duct configured to cool a heatsink coupled to a thermoelectric module (TEM). The cooling duct includes a fan configured to pull air into an inlet duct and onto the heatsink. The air pulled in by the fan absorbs the heat from the heatsink. The cooling duct further includes an exhaust duct connected to the fan and configured to expel the heated air. The exhaust duct is configured to expel the heated air outside the chemical cabinet and away from the TEM.

Implementing barriers for controlled environments during sample processing and detection
11648554 · 2023-05-16 · ·

Provided herein are methods for processing and/or detecting a sample. A method can comprise providing a barrier between a first region and a second region, wherein the first region comprises the sample, wherein the barrier maintains the first region at a first atmosphere that is different than a second atmosphere of the second region, wherein a portion of the barrier comprises a fluid in coherent motion; and using a detector at least partially contained in the first region to detect one or more signals from the sample while the first region is maintained at the first atmosphere that is different than the second atmosphere of the second region. The portion of the barrier comprising fluid may have a pressure lower than the first atmosphere, the second atmosphere, or both.