A dispensing device includes a housing having at least one pressure chamber, having a supply opening for the supply of liquid into the pressure chamber and having a multiplicity of conduits between the pressure chamber and an external side of the housing, there being situated in each of the conduits a tube, the first end of which protrudes into the pressure chamber and the second end of which protrudes out of the housing on the external side.

A system and associated method for concentrating and separating components of different densities from fluid containing cells using a centrifuge includes a syringe and a syringe holder, the syringe having a proximal top with a luer port, a sidewall extending from the top forming a syringe tube, and a plunger slidably disposed inside the syringe tube, the plunger forming a sealing engagement with the sidewall, the syringe holder defining a cavity for receiving the syringe, wherein a distal end of the syringe tube is at least partially closed by the syringe holder after the plunger is placed inside the syringe tube. The method includes receiving a fluid containing cells in the syringe; placing the syringe and syringe holder into a centrifuge; exposing the syringe and syringe holder to elevated g force in the centrifuge, the syringe holder being in physical contact with the sidewall on the distal end to provide support and prevent fluid from leaking outside the syringe; removing the syringe from the centrifuge; and extracting separated layers containing cells using the luer port of the syringe as an access port.

A syringe-based device includes a housing, a pre-sample reservoir, and an actuator. The housing defines an inner volume between a substantially open proximal end portion and a distal end portion that includes a port couplable to a lumen-defining device. The pre-sample reservoir is fluidically couplable to the port to receive and isolate a first volume of bodily fluid. The actuator is at least partially disposed in the inner volume and has a proximal end portion that includes an engagement portion and a distal end portion that includes a sealing member. The engagement portion is configured to allow a user to selectively move the actuator between a first configuration such that bodily fluid can flow from the port to the pre-sample reservoir, and a second configuration such that bodily fluid can flow from the port to a sample reservoir defined at least in part by the sealing member and the housing.

The presently disclosed subject matter provides devices and methods for sample extraction from a swab during biological sample processing. In particular embodiments, the devices and methods are configured for use in conjunction with microfluidic devices for sample processing.

Multivolume liquid pipettes with nested plunger and vacuum chamber configurations and methods of using such pipettes are disclosed herein. These pipettes typically include a body and a fluid displacement assembly with a small plunger element slideably received within a larger plunger element, each movable within a vacuum chamber for the precise and accurate control of the displacement of fluid, such as air. In turn, this allows for a single device to aspirate and dispense a broad range of liquids in a dynamic, accurate, and precise manner. In addition, the devices disclosed herein may also include a multi-tiered spring-loaded ejection mechanism to allow the user to use and eject pipette tips of different sizes.

Fluid assembly for use in a fluid system, having a control module including a processing unit for processing control commands into individual electrical control signals with individually adjustable control signal levels and a control signal level electrically connected to the processing unit, with a power unit, which has a power module for converting the control signals into individual electrical control currents as a function of the control signal levels and an output interface electrically connected to the power module, wherein the processing unit is designed to provide a first group of control signals in a first time interval which can be individually predetermined for each control signal and to provide a second group of control signals in a second time interval which can be individually predetermined for each control signal and follows the respective first time interval, wherein the first control signal and the second control signal are selected in such a way that the control currents in the first time interval are greater than the control currents in the second time interval.

The present invention provides a pipette tip, which can be used in in-vitro diagnostics, in particular in the diagnostic testing of body fluids, such as in coagulation testing. The Pipette tip contains two constituents in a spatially separated manner. The present invention furthermore provides a method of performing such diagnostics, e.g. coagulation analysis, and to the use of the pipette tip in such diagnostic testing.

Embodiments of lab automation workstations are disclosed in which the pod that performs pipetting operations is integrated with pipette tip-loading functionality. To generate the necessary tip-loading force, a dual drive system is used that is symmetric about the Y-axis to allow for offset or partial tip box loads by dynamically centering the drive force (e.g., the tip-loading force) over the reaction load. This minimizes the need for oversized linear motion components while still allowing for the generation of high tip-loading forces needed to properly load a large number of pipette tips simultaneously.

A tool for the distribution of a sample of biological or microbiological material, the tool including an elongated body, provided with a first portion and a second portion; a distributing element, the distributing element being configured at least for distributing a sample of biological or microbiological material on a culture medium; a connector being configured for allowing the joining of the tool with a supporting element of a machine configured for carrying out a distribution of a sample of biological or microbiological material, in particular of a pipetting machine; wherein the connector is adapted and specifically configured for being removably coupled to a supporting element in alternative to another tool, in particular to a tip or pipette for the collection and/or deposit of the sample of biological or microbiological material.

A multi-channel parallel pretreatment device includes a magnetic separation and transfer device and a first drive device. The magnetic separation and transfer device includes a second mounting bracket provided therein with an injector chamber. A mounting plate is provided above the top of the injector chamber and is provided with multiple piston rods that are connected to the injector chamber in a movable and sealing manner. The second mounting bracket is further provided thereon with a second drive device. The injector chamber is provided with loading heads that have a hollow structure. The piston rods have free ends that are provided with magnetic rods. The second drive device can drive the magnetic rods on the piston rods to pass through the loading heads. The first drive device and the second drive device realize the reciprocation of the loading heads.