The present invention provides systems, devices, and methods for point-of-care and/or distributed testing services. The methods and devices of the invention are directed toward automatic detection of analytes in a bodily fluid. The components of the device can be modified to allow for more flexible and robust use with the disclosed methods for a variety of medical, laboratory, and other applications. The systems, devices, and methods of the present invention can allow for effective use of samples by improved sample preparation and analysis.

A pipette tip made of plastic with an elongated tubular body with a lower opening at the lower end for the passage of liquid and an upper opening at the upper end for clamping onto an attachment of a pipetting device, wherein a seating region for the attachment is present next to the upper opening on the inner circumference of the tubular body, wherein at least one flattened area extending in the axial direction is present next to the upper opening on the outer circumference of the tubular body, the wall thickness of the tubular body gradually decreases in a cross-section through the tubular body, starting from one of the two regions of the tubular body adjoining the flattened area, in the flattened area towards its central region, and the flattened area has in the cross-section through the tubular body a straight or a less strongly curved profile than the adjoining regions.

The present invention relates to test devices comprising one or more retaining members for removably retaining a sample applicator, sample applicators for use with such test devices, and kits comprising test devices and sample applicators of the invention.

Provided herein are a system, kit and methods that allow quick and precise detection, identification and quantification of analytes in liquid samples. The kit may be used in automated and pre-programmed singleplexed and multiplexed detection and quantification of one or more analytes in a liquid samples. The kit may include a chip caddy, consumable assay chips, an electrode assembly, an electrical connector assembly, one or more cables, a voltage supply, a vacuum pump, a vacuum trap, custom-designed manifolds, one or more buffers, reagents and instructions for use.

In one example in accordance with the present disclosure, a fluidic ejection controller is described. The fluidic ejection controller includes a firing board to pass electrical control signals for ejecting fluid from a fluidic ejection device. An ejection board of the fluidic ejection controller is electrically coupled to, and selectively removable from, the firing board to pass the electrical control signals to the fluidic ejection device. Electrical pins are disposed on the ejection board in a pattern that matches a pattern of electrical pads on the fluidic ejection device. The electrical pins interface with corresponding electrical pads to pass the electrical control signals from the ejection board to the fluidic ejection device.

An automatic liquid transfer optimization pipetting apparatus and method is disclosed. Namely, a liquid handling apparatus includes a pump supplying a nozzle (i.e., a pipette tip) via a conduit, one or more pressure sensors, and an electronic controller, and wherein the pipette tip is submerged in a liquid. Further, a method of automatic liquid transfer optimization pipetting includes the steps of actuating the pump to move a designated volume of liquid and then allowing the system to settle to a steady state after completion of pump actuation.

An adapter for connecting an array of pipette tips having through bores with conical upper ends to a multichannel air displacement pipettor having a plurality of ports with compliant internal sealing surfaces. The adapter comprises a planar base with an array of openings extending between its top and bottom surfaces. Sealing tubes project upwardly from the top surface, and tip mounting tubes project downwardly from the bottom surface, with pairs of sealing tubes and tip mounting tubes being arranged coaxially and in communication with respective ones of the openings in the base. The tip mounting tubes are externally dimensioned and configured for insertion into the conical upper ends of the pipette tips, and the sealing tubes are externally configured and dimensioned for insertion into the ports of the pipettor and into sealing interengagement with their compliant internal sealing surfaces.

A system and method for printing cells in a medium. A multi-dimensional printer, stably constructed of low-mass parts, can include a computer numerically controlled system that can enable motors driving delivery systems. The motors can include encoders that can enable achieving arbitrary resolution. The motors can drive ballscrews to enable linear motion of delivery systems, and the delivery systems can enable printing of a biological material in a pre-selected pattern in a petri dish. The petri dish can accommodate a medium such as a gel, and can further accommodate a vision system that can detect actual position and deflection of the delivery system needle. The printer can accommodate multiple delivery systems and therefore multiple needles of various sizes.

According to an example aspect of the present invention, there is provided a method, comprising: providing a wearable electronic device that is configured to be worn by a user of a laboratory device; by means of the wearable device, retrieving user data that is specific to said user; and on the basis of the retrieved user data, providing a functionality for control of the laboratory device.

The present invention relates to an automatic real-time quantitative amplification system which can perform analysis of various biological samples, and more particularly to an automatic real-time quantitative amplification system in which a plurality of decks for respectively accommodating biological samples are put in a deck storing/transferring device, whereby it is possible to automatically analyze an amount or existence of a target substance containing a target nucleic acid in the biologic sample, such as a particular gene, a particular, a particular pathogenic bacterium and a particular protein, by amplifying the target nucleic acid purified by some processes of purification, purification after culture, or purification after reaction of the target substance contained in the biological sample and then checking an amount of the amplified target nucleic acid.