A tubular structure for producing droplets and a method of using the tubular structure to produce droplets are provided. The tubular structure includes microchannel structures, and is used for droplet generation, droplet collection, nucleic acid amplification and/or in situ droplet detection, etc.

The present disclosure relates to, inter alia, an easy-to-operate, fully closed component, which can be part of an instrument, for purification of biomolecules from biological samples, and subsequent transfer, and testing of the biomolecules, as well as an instrument comprising the component, and a method for using the component.

Methods and apparatus to mitigate bubble formation in a liquid are disclosed. An example apparatus disclosed herein includes a bottom wall, a first baffle cantilevered from the bottom wall, and a second baffle cantilevered from the bottom wall. The first baffle is spaced apart from the second baffle, and the first baffle and the second baffle are positioned radially relative to an axis of rotation of the apparatus.

A handheld solids dispenser. The dispenser includes a housing defining an inlet passage and an outlet passage. A delivery mechanism is supported within the housing and is positioned between the inlet passage and the outlet passage. Actuation of the delivery mechanism causes the delivery mechanism to transport a desired amount of solids material from the inlet passage to the outlet passage. The delivery member may be in the form of a plunger slidably positioned within the housing. The delivery mechanism may be in the form of a screw conveyor driven by a drive motor.

A container (100) having a first end (102) a second end (104), and a deformable middle portion (106) and methods for manufacturing the container are disclosed. The container has a collapsed configuration and an expanded configuration. The first and second ends are rigid. The container is configured to store cell culture solution powder. Methods and systems (e.g., a dispenser) for creating culture solution using the container are also disclosed.

To provide a reagent cooler reduced in size as compared with that in the related art by reducing a thickness of a heat insulation material of the reagent cooler, and an automated analyzer including the reagent cooler. In the reagent cooler of the automated analyzer, a vacuum heat insulation material is disposed in a periphery (on a side surface, or/and upper and lower portions) of a cooling jacket of the reagent cooler. Then, an end portion of the vacuum heat insulation material is disposed at a position shifted from upper and lower end portions and a side surface end portion of the cooling jacket and a distance between the end portion of the vacuum heat insulation material and the cooling jacket is taken as much as possible.

A reagent management apparatus utilizing a flexible sheet that is foldable along scores into a disposable liner which may be freestanding via a “three point” structure. The disposable liner includes a reservoir for reagents and allows the pouring off of unused reagent into a storage container. The disposable liner may be used with a permanent base in certain cases.

A physical quantity detection device including a container that is formed with an accommodation space accommodating a detection object formed of a dielectric, a first electrode and at least one second electrode that face with each other via the accommodation space, and an electrostatic capacitance detector that detects an electrostatic capacitance between the first electrode and the second electrode by applying an alternating current voltage between the first electrode and the second electrode. A frequency of the alternating current voltage applied between the first electrode and the second electrode is 1 kHz or higher.

A nucleic acid extracting device includes a reagent containing unit, a mixing unit, and a flow channel unit. The reagent containing unit contains a specimen, a magnetic bead, and a reagent for extracting. The mixing unit includes a mixing chamber and a stirring assembly. The mixing chamber includes a chamber portion and a tube portion. The stirring assembly includes a main body and an extension. The main body is provided in the chamber portion. The tube portion connects the chamber portion. And the extension connects the main body and extends into the tube portion. The extension and an inner wall of the tube portion have first and second gaps therebetween respectively along first and second directions of the tube portion. The first gap is less than the second gap. The flow channel unit is connected between the reagent containing unit and the mixing unit.

A unique novel reagent container device with a unique grid structure that allows for the sealing of liquids including volatile liquids. The reagent container device of the present disclosure comprises a container that can be sealed and a support system that forms a grid for sealing the top of the container. Such support system does not restrict liquid flow nor forms an additional section or well within the container device.