A device comprising a base and a support structure is disclosed. The base includes a vial receptacle for holding a vial. The support structure is coupled to an upper portion of the base and is configured to align a pipette comprising a pipette tip vertically over the vial receptacle. The support structure is configured to support a pipette such that an end of a pipette tip is positioned one or more predetermined depths within a vial in the vial receptacle.

A method for withdrawing a solution comprising a plurality of particles from a vial is disclosed. The method includes agitating the vial at a first predetermined mixing speed to suspend the plurality of particles in the solution. The method also includes withdrawing, during the agitating, a first volume of the solution from the vial with a pipette, such that an end of a pipette tip is positioned at a first predetermined depth within the vial.

A method for preparing an aliquot of solution comprising a plurality of particles is disclosed. The method includes agitating the solution with a baffle at a predetermined mixing speed to suspend the plurality of particles in the solution, wherein the baffle positioned at least partially within a vessel containing the solution, and wherein the vessel is engaged with a vessel receptacle configured to hold the vessel. The method also includes withdrawing, during the agitating, the aliquot of solution from the vessel with a pipette, such that an end of a pipette tip is positioned within the vessel.

A suction arm advances in an axial direction of a pipette tip such that an end of the pipette tip comes into contact with a bottom surface of a sample container while the pipette tip attached to a suction arm is tilted with respect to a vertical direction. Next, the suction arm is moved such that the end of the pipette tip scans the bottom surface of the sample container in a horizontal direction toward a predetermined position. Subsequently, at the predetermined position, the suction arm is further tilted by a predetermined angle such that the end of the pipette tip is lifted and a base of the pipette tip is lowered. Thereafter, the suction arm performs a sucking operation such that a sample is sucked through the end of the pipette tip.

A method and device for displacing fluid from a reagent cartridge (310) into a microfluidic device (320) and for loading the fluid into the reagent cartridge (310). The reagent cartridge (310) may include a cartridge body and a pipette array with pipette tips (315) to engage inlets of a microfluidics or other cartridge, wherein the pipette tips (315) correspond in position to the plurality of inlets (325) of the microfluidic device (320). Fluid may be loaded into or displaced from the microfluidic device (320) by a system of plungers (615). The reagent cartridge may alternatively include blisters (925) having fluid reservoirs and dispensing tips (930), each dispensing tip (930) including a pathway (927) that is fluidly coupled to a blister (925). The fluid may be displaced from or loaded into the blister (925) via the dispensing tip (930). A deformable seal (910) may be overlaid on the blisters (925) to seal the volumes of fluid within the blisters (925), and may be deformed to displace the fluid.

Disclosed is a fluid disposing system including a centrifugal separator that centrifugally separates a liquid that is supplied, a reagent supply module provided on one side of the centrifugal separator and that supplies a reagent to the centrifugal separator, a pipetting module provided at an upper portion of the centrifugal separator and that feeds a fluid to the centrifugal separator, a feeding module coupled to one side of the pipetting module, and that moves the pipetting module in an X axis direction and a Y axis direction corresponding to a horizontal direction, and a Z axis direction that is perpendicular to the horizontal direction, and a separation module including a magnetic bead for magnetically separating a material that has been primarily separated by the centrifugal separator.

The invention concerns pipette tips for connecting to a pipette tube of a pipetting device are used for taking up and discharging fluids. The pipette tip is in the shape of an elongated tube forming a pipette body that has an opening at one end and is designed for connecting to the pipette tube at the other end. The pipette tip has a first electrode as a volume measuring electrode of a measuring capacitor and a second electrode as an immersion detector electrode. The first electrode is located on an outer surface of the pipette body or is embedded in the pipette body, and the second electrode is located at least partially on an inner surface of the pipette body.

The present invention relates to pipette tips for connecting to a pipette tube of a pipetting device that is used for taking up and dispensing fluids. A pipette tip is shaped as a long tube that forms a pipette body with an opening on one of its ends and the other end is designed to connect to the pipette tube. The pipette tip is characterised in that it has an electrode as a volume measuring electrode of a measuring capacitor. The present invention further relates to pipetting devices with a pipette tip, methods for determining the volume of a fluid sample in such a pipette tip, methods for recognising such a pipette tip on a pipetting device, methods for producing such a pipette tip, uses for such a pipette tip and a set of pipette tips.

An apparatus for limiting pipette motion, the apparatus comprising: (1) a stand for controlling spatial positions; (2) a mechanism for temporally coupling the pipette with the stand; the orientation or the movement of the pipette being restricted by the stand as predetermined for (a) limiting the insertion depth of the pipette tips into sample containers, (b) restricting unwanted movements or rotations of the pipette, or (c) maintaining the desired alignments of the pipette tips with the sample containers. Methods of limiting pipette motion or rotation are also provided.

A process for applying, in a tubular solid support, at least one binding partner P1 to an analyte to be detected or quantified in a test sample, including steps: (i) connect the support to a suction-discharge device, (ii) draw up into the support, by one of its ends, a solution including the binding partner P1, called sensitization solution S1, contained in a container, called container C1, (iii) continue contact between solution S1 and the inner surface of the support for a time between 0 s and 11 min, (iv) discharge the solution S1 into a container, which is optionally the container C1, steps (ii) to (iv) forming a cycle that can be repeated at least once, over a total duration of at least 1 min and at most 2.5 h. Also, the use of the coated support for the detection or quantification of an analyte in a test sample.