In an embodiment, a device includes: an electrode configured to change a contact angle of a liquid droplet above the electrode when a first voltage is applied to the electrode; a sensing film overlaying the electrode, wherein the electrode is configured for assessment of a state of the liquid droplet based on a second voltage sensed at the electrode; a reference electrode above the electrode, the reference electrode configured to provide a reference voltage; and a microfluidic channel between the electrode and the reference electrode, wherein the microfluidic channel is configured to manipulate the liquid droplet using the electrode.

The present invention relates to a test system or an assay system (detection system) and test method preferably for use in the Point-of-Care (PoC) field.

Sample collection tubes and methods of producing the same are provided. Contemplated collection tubes comprise a tube having a separator substance disposed therein. In some aspects, the separator substance preferably maintains a predetermined flowability during irradiation or heat sterilization, and can subsequently polymerize upon exposure to a UV light or other suitable source.

The present invention relates to a tube assembly for dripping. According to an embodiment, a tube assembly for dripping includes a tube (100) having a hole (H) at an upper portion thereof, and a filter tip (200) having a tip (210) including, an insertion part (211) inserted into the hole (H) of the tube (100) and, an expansion part (212) connected to the insertion part (211) and having a diameter that is larger than that of the hole (H), and a discharge pipe (213) connected to the expansion part (212) and acting as a passage, through which a solution (S) stored in the interior of the tube (100) is discharged, wherein a discharge adjusting part (213a) having a discharge hole (h) having a predetermined diameter (d1) is formed in the interior of the discharge pipe (213) that is spaced apart from a lower end of the discharge pipe (213) by a predetermined distance.

A fluid analysis cartridge having an improved structure in order to increase test reliability, and a fluid analysis apparatus including the same are disclosed. The fluid analysis apparatus comprises: a housing having a fluid supply part for supplying a fluid sample, and a filter member arranged such that the fluid sample supplied to the fluid supply part passes therethrough; a fluid analysis cartridge having a test unit that is connected to the housing so that the fluid sample that has passed through the filter member can be introduced and a test can be performed; and a pressure member that is arranged to pressurize the fluid analysis cartridge in order to move the fluid sample supplied to the fluid supply part to the test unit, wherein the test unit includes a first panel that has a first inflow part facing the filter member, and a second panel that is arranged to face the first panel and that has a second inflow part corresponding to the first inflow part, and the first inflow part may have a smaller width than the second inflow part.

A reagent management apparatus utilizing a flexible sheet that is foldable along scores into a disposable liner which may be freestanding via a “three point” structure. The disposable liner includes a reservoir for reagents and allows the pouring off of unused reagent into a storage container. The disposable liner may be used with a permanent base in certain cases.

Sample collection tubes and methods of producing the same are provided. Contemplated collection tubes comprise a tube having a separator substance disposed therein. In some aspects, the separator substance preferably maintains a predetermined flowability during irradiation or heat sterilization, and can subsequently polymerize upon exposure to a UV light or other suitable source. In other aspects, the separator substance preferably includes a soft gel component (thixotropic gel), and a photocurable sealant component that is formulated to polymerize and form a solid barrier between fractions of a liquid.

Compositions, devices, and methods are disclosed for the modification of polymer surfaces with coatings having a dispersion of silicone polymer and hydrophobic silica. The surface coatings provide the polymer surface with high hydrophobicity, as well as increased resistance to biofouling with proteinaceous material. The polymer surfaces can be particularly useful in microfluidic devices and methods that involve the contacting of the covalently modified polymer surfaces with emulsions of aqueous droplets containing biological macromolecules within an oil carrier phase.

A method of partitioning droplets from a fluid reservoir containing particles provides a non-Poissonian distribution of dispensed droplets containing a desired number of particles. The method constitutes a method of operating an electrowetting on dielectric (EWOD) device including the steps of: inputting a fluid reservoir containing particles into the EWOD device; performing an electrowetting operation to dispense a plurality of dispensed droplets from the fluid reservoir; interrogating each droplet with a detector and determining whether each dispensed droplet has a desired number of particles; selecting dispensed droplets that contain the desired number of particles and performing an electrowetting operation to move the selected dispensed droplets to a reaction area on the EWOD device; and rejecting dispensed droplets that do not contain the desired number of particles and performing an electrowetting operation to move the rejected dispensed droplets to a holding area on the EWOD device that is different and spaced apart from the reaction area. The selected droplets may be combined, including with or without a portion of the rejected droplets and/or additional reagent, into a larger reaction droplet that may be used in subsequent reaction protocols.

An inspection chip according to the present invention is an inspection chip for stirring liquid by a circular movement of a bottom surface end, including a well main body for accommodating the liquid and a side wall member arranged on a side surface of the well main body. The bottom surface end has a bottom surface structure in contact with a rotating member for allowing the bottom surface end to perform the circular movement in a position leaning from a center line of the well main body toward the side wall member.