The present disclosure provides a reagent cartridge configured for use in an automated multi-module cell processing environment.

A cartridge for testing a biological sample. The cartridge has a closure element that is fastened to the cartridge in a form-fit or interlocking manner and is a multi-component injection molded closure part having an integrated seal so as to be able to fluidically close a receiving cavity having an integrated vent. The cartridge also has a film cover and an additional aluminum cover in the region of storage cavities for liquid reagents.

The present disclosure provides a reagent cartridge configured for use in an automated multi-module cell processing environment.

A tight connection device for the aseptic transfer of a biopharmaceutical product includes: a stationary temporary clamping means keeping the container hermetically clamped against the chamber; a stationary unlocking means capable of switching the container from an initial locked position to an intermediate unlocked position; a stationary locking means; and an annular functional crown capable of being rotated to actuate the stationary unlocking means and the stationary locking means of the container. The stationary unlocking means and the stationary locking means are mechanically linked to the annular functional crown and arranged such that the rotation of the annular functional crown and the end locked position. The device further includes stationary immobilising/release means capable of allowing and preventing the annular functional crown to rotate.

A method for detecting and counting particles suspended in fluids, such as bacteria suspended in urine, utilizing dynamic features of the suspended particles and employing light scattering measurements. The disclosed method is suitable for determining the susceptibility of bacteria to antibiotics. A cuvette for detecting bacteria in fluids, which is especially suited for the light scattering measurements, is provided.

An assembly (10) (FIG. 1) having a passive beta port (12) and an active alpha port (14), the passive and the active are complementarily shaped such that they can engage with one another. The passive beta port (12) has an annular flange (16) defining an annular opening to which is releasably securable a passive port door (18). Disposed at the distal end of the passive (12), at the opposite end to the annular flange 16 is an annular clamp (22) having two handles (24). Disposed between the annular ring (16) and the annular clamp (22) is the gaiter (26) of the protective member (28). The protective member has a cylindrical body (30) forming a funnel through which material may pass. The free end (32) is sized so as to be capable of passing through the port formed between the alpha and beta ports (12, 14).

The present invention relates to encapsulated microfluidic packages and methods thereof. In particular embodiments, the package includes a device, a cradle configured to support the device, and a lid having a bonding surface configured to provide a fluidic seal between itself and the device and/or cradle. Other package configurations, as well as methods for making such fluidic seals, are described herein.

The present disclosure relates to a specimen collection device comprising ventilation means for drying a collected specimen. The device further comprises a cassette into which the specimen collected is secured to maintain evidentiary chain of custody requirements while providing unobstructed access to a collected specimen for automated analysis. Methods of using the device are also provided.

The invention relates to a container system for transport of biological material comprising a container casing and an insulating device, wherein the container casing defines a container interior space for accommodation of the insulating device and for accommodation of biological material to be transported, and wherein the insulating device is constituted of at least two insulating portions, which are formed so as to surround the biological material inside the container interior space. The invention further relates to uses of such a container system for packaging and transport of biological material, as well as methods of packaging biological material for transport.

Devices and methods are provided that permit efficient and selective separation of liquid biological specimens into at least two constituent components to facilitate subsequent quantitative and qualitative analysis on at least one analyte of interest in at least one of the components. The devices generally include one or more sample deposition regions supported on a base. Each sample deposition region includes a separation membrane for separating the liquid biological specimen into two different fractions. The first fraction is trapped by the separation membrane while the second fraction passes through the separation membrane and into a respective collection membrane. The separation and collection membranes are easily separable from the devices and can be utilized for further processing and analysis.