B01L2300/04

System and method for sex sorting of mosquitoes

A system for sex sorting of mosquitoes generally comprises: (i) a plate or similar receptacle that includes multiple wells, with each of the multiple wells configured to receive a mosquito; and (ii) an imaging subsystem, including a camera for capturing images of the mosquito in each of the multiple wells and a computer for analyzing the captured images to determine whether each mosquito is male or female. Mosquitoes have distinct anatomical areas for identification, which are captured in the images and are used to determine if a mosquito is male or female. Furthermore, in some implementations, the system includes a suction device or other means for exterminating the unwanted mosquitoes after the determination of whether each mosquito is male or female.

Systems, devices and methods for cell capture and methods of manufacture thereof

Embodiments of the current disclosure are directed to systems, methods and apparatus for evaluating single cell secretion profiles. In some embodiments, the apparatus may be configured to analyze substances expressed by a biological cell and may include a first compressible substrate, and a second substrate configured for removable sealing attachment with the first substrate. In some embodiments, upon attachment of the second substrate with the first substrate, an assembly is formed such that the open side of the plurality of chambers are covered by the second substrate, and a portion of each of the plurality of capture areas are exposed in each of the chambers.

Sealed Container Comprising a Device Allowing Removable Connection to an Enclosure
20220371011 · 2022-11-24 ·

The invention relates to a sealed container (1) comprising a container body (2) having a through-hole (8) that is delimited by a flange and is closed by a removable door (7) mounted on the flange, an annular seal (13) located between the flange and the door (7), the flange, the door (7) and the seal forming a sealed connection device that can be connected to a complementary connection device on a sterile enclosure by means of bayonet connection means in order to allow sterile communication between the sealed container and the sterile enclosure, characterized in that the seal (13) comprises, on its inner peripheral circumference, an annular attachment bead (130) for attaching the door (7) to the flange inserted into a notch (70) on the door (7).

Fluid device and fluid control system

A fluid device includes a substrate and a gas-liquid separating filter, the substrate has a flow path through which a solution flows, a reservoir, in which the solution is accommodated, connected to the flow path, an injection hole configured to connect the reservoir to the outside, and an air introduction hole branched off from the injection hole and connected to the outside, and the gas-liquid separating filter is disposed in a path of the air introduction hole, allows passage of a gas flowing through the air introduction hole, and prevents passage of a liquid flowing through the air introduction hole.

Assessment of micro-organism presence

The present disclosure relates to a consumable sample partition device and it assembly and use. The sample partition device can be used to test a sample for absence of microorganisms (sterility) and/or for concentration of said organisms (bio-burden). The sample partition device partitions the sample input volume into multiple discrete measurement zones with little or no loss of sample (e.g., zero-loss) and with little operator involvement, thereby reducing operator- and environment-based false positives.

GAS FLOW AND HEAT TRANSFER APPARATUS
20230053551 · 2023-02-23 ·

An apparatus arranged to hold at least one vessel. The apparatus includes a frame defining a gas flow pathway and having at least one aperture configured to receive a vessel. The apparatus also includes a device for directing a gas flow along the gas flow pathway, such that when a vessel is located in the aperture, the vessel is positioned at least partially in the gas flow pathway such that heat is transferred between the gas flow and the vessel.

Microfluidic Devices and Methods for Use Thereof in Multicellular Assays of Secretion

Methods and devices are provided herein for identifying a cell population comprising an effector cell that exerts an extracellular effect. In one embodiment the method comprises retaining in a microreactor a cell population comprising one or more effector cells, wherein the contents of the microreactor further comprise a readout particle population comprising one or more readout particles, incubating the cell population and the readout particle population within the microreactor, assaying the cell population for the presence of the extracellular effect, wherein the readout particle population or subpopulation thereof provides a direct or indirect readout of the extracellular effect, and determining, based on the results of the assaying step, whether one or more effector cells within the cell population exerts the extracellular effect on the readout particle. If an extracellular effect is measured, the cell population is recovered for further analysis to determine the cell or cells responsible for the effect.

Blood Collection Apparatus
20230055314 · 2023-02-23 ·

A blood collection apparatus comprising: (i) a test tube for storing blood extracted from a patient, the test tube comprising a vacuum facilitating an extraction of blood; (ii) a heat transfer element encapsulating the test tube and storing at least two reagents capable of initiating a heat transfer process contemporaneously with the extraction of the blood, the heat transfer element further comprising a fracturable element that when fractured enables the at least two reagents to initiate the heat transfer process; and (iii) an insulation element encapsulating the heat transfer element, the insulation element inhibiting a loss of a temperature change of the blood, wherein test tube is removable, contemporaneously with an initiation of a blood test, from the insulation element encapsulating the heat transfer element, and wherein the apparatus comprises a circumference suitable to be mated with a general purpose test tube needle holder.

SYSTEMS, DEVICES AND METHODS FOR CELL CAPTURE AND METHODS OF MANUFACTURE THEREOF

Embodiments of the current disclosure are directed to systems, methods and apparatus for evaluating single cell secretion profiles. In some embodiments, the apparatus may be configured to analyze substances expressed by a biological cell and may include a first compressible substrate, and a second substrate configured for removable sealing attachment with the first substrate. In some embodiments, upon attachment of the second substrate with the first substrate, an assembly is formed such that the open side of the plurality of chambers are covered by the second substrate, and a portion of each of the plurality of capture areas are exposed in each of the chambers.

ALL-IN-ONE SELF TEST KIT
20230036013 · 2023-02-02 ·

An all-in-one self test kit includes: a test tool having a reagent container adapted to store a diagnosis reagent therein and a diagnosis kit with a casing constituted of a first body and a second body and a diagnosis strip disposed inside the casing and having a sucking part for sucking the diagnosis reagent and a diagnosis part reacting to the diagnosis reagent sucked to the sucking part; a sub-body having a container insertion portion for inserting the reagent container thereinto and a kit insertion portion for inserting the diagnosis kit thereinto; a main body for inserting the sub-body thereinto; and a cap fastened and unfastened with an entrance of the main body to open and close the main body.