In some embodiments, a stand-alone molecular diagnostic test device includes a detection circuit that includes a light emitting device and a light receiving device (e.g., a photodiode) that are arranged to produce an electronic signal associated with a colorimetric output produced by the stand-alone molecular diagnostic test.

A method of performing an optical measurement of an analyte in a processed biological sample using a cartridge is provided. The cartridge is operable for being spun around a rotational axis. The method comprises: placing the biological sample into a sample inlet; controlling the rotational rate of the cartridge to process a biological sample into the processed biological sample using a fluidic structure; controlling the rotational rate of the cartridge to allow the processed biological sample to flow from the measurement structure inlet to an absorbent structure via a chromatographic membrane, and performing an optical measurement of a detection zone on the chromatographic membrane with an optical instrument. An inlet air baffle reduces evaporation of the processed biological sample from the chromatographic membrane during rotation of the cartridge.

The present invention provides methods and devices for simple, low power, automated processing of biological samples through multiple sample preparation and assay steps. The methods and devices described facilitate the point-of-care implementation of complex diagnostic assays in equipment-free, non-laboratory settings. The invention includes a microfluidic device comprising a reagent-dispensing unit, a sample extraction device and a specimen processing unit.

Provided herein are compositions, methods, assays, and devices for diagnosing and treating a viral infection in a subject and/or detecting a viral nucleic acid in a sample. In one example, a sample is treated in a first chamber and via a closing or twisting operation, the sample is flowed into a second chamber, where any pathogenic nucleic acid is detected by oligonucleotides that are specific to the pathogen under test. Further, the oligonucleotides comprise are cleavage site for a restriction enzyme in the second chamber, which cleaves oligonucleotide-pathogenic nucleic acid hybrid resulting in the exposure of an enzyme that was being held by the oligonucleotide to its substrate, which generates a colorimetric and/or another visual readout (e.g., foam formation). Further, the methods, device, or kits provided herein can be used to detect SARS-CoV-2 in a saliva sample from a human subject as a rapid in home diagnostic test for COVID-19.

The invention relates to a container system for transport of biological material comprising a container casing and an insulating device, wherein the container casing defines a container interior space for accommodation of the insulating device and for accommodation of biological material to be transported, and wherein the insulating device is constituted of at least two insulating portions, which are formed so as to surround the biological material inside the container interior space. The invention further relates to uses of such a container system for packaging and transport of biological material, as well as methods of packaging biological material for transport.

This system takes in raw cellular material collected using a provided swab, blood collection device, urine collection device, or other sample collection device and transforms that biological material into a digital result, identifying the presence, absence and/or quantity of nucleic acids, proteins, and/or other molecules of interest.

Provided are a PCR tube that can reliably perform management of a sample, and an RFID sample management system and an RFID sample management method using the PCR tube. The PCR tube 40 includes a tube body 42 that has an opening at one end and has a collar part 46 around the opening, and a lid part 44 that is attachably and detachably mounted on the tube body 42 and seals the opening of the tube body 42 at the time of the mounting. An RFID tag 48 having a passive antenna built therein is provided at the collar part 46 or the lid part 44, and the antenna has directivity in a direction opposite to a bottom face 42a of the tube body 42.

The invention relates to a collection assembly (1) for small amounts of body fluids, comprising a sample container (2) and an extender element (3). The sample container (2) has a base (13) and a container wall (5) with a first container wall section (6) and a second container wall section (7) adjoining same. The second container wall section (7) is formed hollow-conically and projects into the extender element (3). Moreover, a coupling device (25) with a first coupling element (26) and a second coupling element (27) is provided. When the coupling elements (26, 27) are in coupled engagement, the extender element (3) is coupled to the sample container (2) in a positively locked manner in the form of a snap connection establishing the collection assembly (1).

In a method for performing ultrasound tests which uses a suitable device for performing such tests, a well plate implements an insulation between the different wells of the plate of such set, without significant reflections of ultrasounds which could alter the test itself since the well plate is covered by means for closing said wells which insulates the content thereof by wholly covering the well plate and having a sound transmission speed which differs from that of the transmission liquid in the bath no more than +/−15%.

A test sensor container for use with an analyte measuring system may include a cartridge that includes a base, two opposite sidewalls extending away from the base, and a plurality of compartments each dimensioned to hold a test sensor. At least one of the two opposite sidewalls is oriented at an acute angle relative to a reference axis that is perpendicular to the base. The test sensor container may further include at least one foil cover sealing the plurality of compartments and an ejection mechanism.