A temperature and humidity chamber type apparatus for taking potential impact marks according to an embodiment includes: a specimen treated with an amino acid reaction reagent to react with potential impact marks to take the potential impact marks; a chamber in which a receiving space for receiving the specimen is secured; a door for opening and closing the chamber; a supporter formed in the receiving space to receive the specimen; an adjuster for adjusting temperature and humidity in the chamber within a set application time range to take the potential impact marks; a display unit attached to one side of the outside of the chamber to display an operation state in the chamber; a power source; a controller for controlling setting of temperature, humidity, and an application time in the chamber; and an input unit in which the controller operates according to a user's input.

An implement for eliminating headspace in the testing space(s) (T.sub.9 or MP.sub.Well) of a test tube (T) or microtiter plate (MP), and methods of using such implements to measure oxygen concentration in a test sample. The implement projects into a test chamber (T.sub.9 or MP.sub.Well) to displace a portion of a fluid sample within the test chamber (T.sub.9 or MP.sub.Well) and has longitudinally extending grooves (109 and 229) through which the displaced fluidic content can be discharged from the test chamber (T.sub.9 or MP.sub.Well).

An insulated chamber having an interior region for storing items therein includes a phase change material to facilitate controlling the temperature of the interior region and the items. A heating device or cooling device may be used to melt or freeze the phase change material. The phase change material (PCM) may be in various locations such as the walls of the chamber in the form of packets or in the form of containers that serve as shelves and may be removable from the interior region. The packets may have recesses for receiving the items. The phase change material may be within capsules that may be within a liquid or a solid matrix. Controls may be provided to control humidity, oxygen, and carbon dioxide within the interior chamber.

Methods of removing bubbles from a microfluidic device are described where the flow is not stopped. Methods are described that combine pressure and flow to remove bubbles from a microfluidic device. Bubbles can be removed even where the device is made of a polymer that is largely gas impermeable.

Methods of removing bubbles from a microfluidic device are described where the flow is not stopped. Methods are described that combine pressure and flow to remove bubbles from a microfluidic device. Bubbles can be removed even where the device is made of a polymer that is largely gas impermeable.

An integrated system for processing and preparing samples for analysis may include a microfluidic device including a plurality of parallel channel networks for partitioning the samples including various fluids, and connected to a plurality of inlet and outlet reservoirs, at least a portion of the fluids comprising reagents, a holder including a closeable lid hingedly coupled thereto, in which in a closed configuration, the lid secures the microfluidic device in the holder, and in an open configuration, the lid is a stand orienting the microfluidic device at a desired angle to facilitate recovery of partitions or droplets from the partitioned samples generated within the microfluidic device, and an instrument configured to receive the holder and apply a pressure differential between the plurality of inlet and outlet reservoirs to drive fluid movement within the channel networks.

Cap arrangements for per-well fluidics and gas exchange for microplate, microtiter, and microarray technologies are presented for use with cell cultures or other applications. In example implementations, each individual well within in a conventional or specialized microplate can be fully or partially isolated with capping or other arrangements which can include conduits for controlled introduction, removal, and/or exchange of fluids and/or gases. Conduit networks can include small controllable valves that operate under software control, and micro-scale pumps can also be included. Conduit interconnections can include one or more of controllable-valve distribution buses, next-neighbor interconnections, and other active or passive interconnection topologies. Cap arrangements within the lid can include or provide one or more sensors of various types, including but not limited to selective gas sensors, chemical sensors, temperature sensors, pH sensors, biosensors, immunosensors, molecular-imprint sensors, optical sensors, fluorescence sensors, bioFETS, etc. Incubator interfacing and imaging are described.

Methods of removing bubbles from a microfluidic device are described where the flow is not stopped. Methods are described that combine pressure and flow to remove bubbles from a microfluidic device. Bubbles can be removed even where the device is made of a polymer that is largely gas impermeable.

A multifunctional dual mode microfluidic device including a first operating configuration and a second operating configuration wherein in the first operating configuration, the device is configured to perform static cell seeding or produce cells. In the second operating configuration, the device is configured to perform perfusion via microfluidics of the device, and the device is configured to switch between the first operating configuration and the second operating configuration. The first operating configuration and the second operating configuration are selectively and independently accessible, wherein the first operating configuration or the second operating configuration does not alter any other configuration of the device. The device is fully operable in either one of the first operating configuration or the second operating configuration.

The invention relates to a microfluidic device including a chamber having a fluid inlet, a fluid outlet and a sealable port. In some embodiments, the fluid inlet and the fluid outlet may be positioned to direct fluid flowing from the fluid inlet to the fluid outlet through the chamber. Various embodiments may include a sealable port which may be aligned with the chamber to allow material to be placed directly into, or removed from, the chamber from the exterior of the device when the sealable port is open, and to inhibit and/or prevent fluid escaping through the sealable port when the port is sealed.