Disclosed are a continuous low-temperature plasma powder treatment and ball-milling production device, and a method thereof. The device includes a powder circulating and conveying pipeline system (1), a ball mill (2), a low-temperature plasma discharge pipeline (3), a vacuum discharge system (4) and a controllable atmosphere system (5), where the powder circulating and conveying pipeline system (1) is sequentially connected to the ball mill (2) and the low-temperature plasma discharge pipeline (3) through pipelines; and the controllable atmosphere system (5) is connected to the powder circulating and conveying pipeline system (1). The powder circulating and conveying pipeline system (1) is used for circulating and conveying to-be-treated powder at a controllable air pressure and flow speed. On one hand, a double-dielectric barrier discharge structure is introduced in a powder conveying process to form the low-temperature plasma discharge pipeline (3), thereby realizing a plasma discharge treatment on a transfer material powder; and on the other hand, the ball mill (2) is introduced to perform ball-milling refining or alloying on a powder subjected to plasma discharge treatment, thereby treating the powder through a large-area, uniform and high-energy non-equilibrium plasma in cooperation with mechanical ball milling and being capable of being used for performing a surface circulating modification treatment on a conventional metal, macromolecule or oxide powder.

An active/resilient grinding media inside a tube containing a sample is oscillated rapidly by a homogenizer so that the active media is driven in a first direction until it impacts a first end of the tube, which causes it to deform and store an energy charge as it decelerates and stops, and it then accelerates rapidly in the second opposite direction under the discharging force of the stored energy toward the opposite second end of the tube. This cycle of the active media decelerating/charging and then discharging/accelerating is repeated throughout the entire oscillatory processing of the sample. The result is much higher velocities of the active media and therefore much greater impact forces when the sample and active media collide, producing increased efficiency in disruption and size-reduction of the sample particles.

A vibratory drum includes a tubular drum having a longitudinal axis, and first and second vibratory generators disposed laterally relative to the longitudinal axis and opposite each other across the tubular drum. The drum also includes a frame to which the first and second vibratory generators are attached; and a plurality of resilient elements attached at a first end to the tubular drum and at a second end to the frame, whereby the vibratory motion of the generators is transferred to the tubular drum to impart a circular motion to material disposed in the tubular drum.

The invention shows and describes a vibration mill for at least two grinding beakers performing vibrations in the horizontal position, with at least one multi-part pendulum drive, wherein the pendulum drive has at least one eccentric shaft mounted to rotate about a vertical eccentric axis, and at least two rockers each mounted so as to be capable of vibrating about a vertical vibration axis and connected by means of couplers to the eccentric shaft, said rockers holding the grinding beakers. The pendulum drive further has a motor unit coupled to the eccentric shaft as a drive for the eccentric shaft and optionally further components, wherein a rotary movement of the eccentric shaft via the couplers can be converted into a vibrating movement of the rockers. According to the invention, the centre of gravity of the pendulum drive in a horizontal centre of gravity plane is substantially equidistant from both vibration axes.

The present invention relates to methods for producing particles of a biologically active material using dry milling processes as well as compositions comprising such materials, medicaments produced using said biologically active materials in particulate form and/or compositions, and to methods of treatment of an animal, including man, using a therapeutically effective amount of said biologically active materials administered by way of said medicaments.

The present invention relates to methods for producing particles of a biologically active material using dry milling processes as well as compositions comprising such materials, medicaments produced using said biologically active materials in particulate form and/or compositions, and to methods of treatment of an animal, including man, using a therapeutically effective amount of said biologically active materials administered by way of said medicaments.

Generating plasma by using dielectric barrier discharge and introducing a dielectric barrier discharge electrode bar into a high-speed vibrating ball milling tank requires that, on one hand, a solid insulation medium on the outer layer of the electrode bar can simultaneously bear high-voltage discharge and mechanical shock failure of the grinding ball, and on the other hand, the high-speed vibrating ball milling device can uniformly process the powder. The discharge space pressure is set to a non-thermal equilibrium discharge state with a pressure of about 10.sup.2 to 10.sup.6 Pa, discharge plasmas are introduced to input another kind of effective energy to the processed powder, so as to accelerate refinement of the powder to be processed and promote the alloying process and improve the processing efficiency and the effect of the ball mill.

Generating plasma by using dielectric barrier discharge and introducing a dielectric barrier discharge electrode bar into a high-speed vibrating ball milling tank requires that, on one hand, a solid insulation medium on the outer layer of the electrode bar can simultaneously bear high-voltage discharge and mechanical shock failure of the grinding ball, and on the other hand, the high-speed vibrating ball milling device can uniformly process the powder. The discharge space pressure is set to a non-thermal equilibrium discharge state with a pressure of about 10.sup.2 to 10.sup.6 Pa, discharge plasmas are introduced to input another kind of effective energy to the processed powder, so as to accelerate refinement of the powder to be processed and promote the alloying process and improve the processing efficiency and the effect of the ball mill.

A method of grinding large sample quantities using a bead beater homogenizer includes steps of loading a sample material into a vial having a size of 500 ml or greater having a chamber enclosed by two end walls and a cylindrical sidewall defining a central vial axis, loading a plurality of balls into the vial with the sample material, securing the vial to a movable platform of the homogenizer, and oscillating the platform in a back-and-forth motion isolated to a movement axis, thereby causing the balls to move in a circular motion along the cylindrical sidewall, wherein the central vial axis is perpendicular to the movement axis. A system of a cylindrical vial and a bead beater homogenizer is also provided.

A method of grinding large sample quantities using a bead beater homogenizer includes steps of loading a sample material into a vial having a size of 500 ml or greater having a chamber enclosed by two end walls and a cylindrical sidewall defining a central vial axis, loading a plurality of balls into the vial with the sample material, securing the vial to a movable platform of the homogenizer, and oscillating the platform in a back-and-forth motion isolated to a movement axis, thereby causing the balls to move in a circular motion along the cylindrical sidewall, wherein the central vial axis is perpendicular to the movement axis. A system of a cylindrical vial and a bead beater homogenizer is also provided.