The present disclosure provides antibody cytokine engrafted proteins that bind to and stimulate intracellular signaling through a high affinity interleukin receptor. The antibody cytokine engrafted proteins find use in enhancing anti-inflammatory cell responses, and reducing pro-inflammatory effects in the treatment, amelioration and prevention of immune related disorders such as Type 1 Diabetes.

The present disclosure provides antibody cytokine engrafted proteins that bind to and stimulate intracellular signaling through a high affinity interleukin receptor. The antibody cytokine engrafted proteins find use in enhancing anti-inflammatory cell responses, and reducing pro-inflammatory effects in the treatment, amelioration and prevention of immune related disorders such as Type 1 Diabetes.

A method for separating composite materials and mixtures, in particular solid-material mixtures and slags, and to a device for carrying out said method. The method for separating composite materials and mixtures comprises the step of transporting the composite material or the mixture through a separating device. The composite material to be separated or the mixture to be separated is excited by mechanical impulses as it passes through the separating device and is thereby separated. The device (1) for carrying out the method comprises a drive unit (21) for driving a rotor element (32), which is connected to a bearing/shaft unit (22) and which is part of a rotor unit (31). The rotor element itself has at least one rotor tool (33) and each rotor tool has at least one rotor tool component (34) and is surrounded by a stator element (42), which is part of a stator unit (41). The stator element itself has at least one stator tool (43) and each stator tool has at least one stator tool component (44). The rotor element and the stator element are substantially cylindrical.

A method for separating composite materials and mixtures, in particular solid-material mixtures and slags, and to a device for carrying out said method. The method for separating composite materials and mixtures comprises the step of transporting the composite material or the mixture through a separating device. The composite material to be separated or the mixture to be separated is excited by mechanical impulses as it passes through the separating device and is thereby separated. The device (1) for carrying out the method comprises a drive unit (21) for driving a rotor element (32), which is connected to a bearing/shaft unit (22) and which is part of a rotor unit (31). The rotor element itself has at least one rotor tool (33) and each rotor tool has at least one rotor tool component (34) and is surrounded by a stator element (42), which is part of a stator unit (41). The stator element itself has at least one stator tool (43) and each stator tool has at least one stator tool component (44). The rotor element and the stator element are substantially cylindrical.

Methods for forming black phosphorus alloys and exfoliating black phosphorus alloys. A method for forming black phosphorus alloys includes providing phosphorus inside a vessel and providing an element inside the vessel. Media is provided inside the vessel and the phosphorus, the element, and the media are sealed under a gas within the vessel. The phosphorus and the element are mechanically milled with the media to produce black phosphorus that is covalently bonded with the element. A method for exfoliating a black phosphorus alloy includes mixing a milled black phosphorus alloy with a solvent and mixing a milled black phosphorus alloy with a solvent. The milled black phosphorus alloy and solvent mixture are then extracted from the milling apparatus, which may be a planetary ball mill, a vibratory mill, a tumbler ball mill, a mixer mill, a rod mill, an attrition mill, or a shaker mill.

Methods for forming black phosphorus alloys and exfoliating black phosphorus alloys. A method for forming black phosphorus alloys includes providing phosphorus inside a vessel and providing an element inside the vessel. Media is provided inside the vessel and the phosphorus, the element, and the media are sealed under a gas within the vessel. The phosphorus and the element are mechanically milled with the media to produce black phosphorus that is covalently bonded with the element. A method for exfoliating a black phosphorus alloy includes mixing a milled black phosphorus alloy with a solvent and mixing a milled black phosphorus alloy with a solvent. The milled black phosphorus alloy and solvent mixture are then extracted from the milling apparatus, which may be a planetary ball mill, a vibratory mill, a tumbler ball mill, a mixer mill, a rod mill, an attrition mill, or a shaker mill.

The present invention relate to a waste mask treatment device using a sterilizing material, and more particularly, to a waste mask treatment device including: a body with an inlet adapted to insert a waste mask thereinto; a pulverization part located inside the body to pulverize the waste mask into pieces of mask; a sterilization part for emitting a sterilizing material for sterilizing the pieces of mask; and a collection part for collecting the pieces of mask. Accordingly, the waste mask treatment device is capable of being conveniently movable, being compact in size, and eliminating more than 99.99% of harmful bacteria living on the disposable mask through the sterilizing material.

A fertilizer grinding mechanism, a water and fertilizer mixing device, and an aqueous fertilizer solution preparation production line. A fertilizer receiving body, where an edge is provided with a arranged first channel; a connecting body, fixed to a bottom of the fertilizer receiving body and provided with a second channel with the first channel, a bottom of the second channel is communicated with a buffer bin, a pushing block is arranged in the buffer bin, and the pushing block is connected with a drive mechanism for driving the block to move in direction of the body; and an inner grinding block, where the block is fixed to a bottom of the connecting body, an outer side of the inner grinding block is with a vertically movable grinding roller, the pushing block can push fertilizer under vertical movement of the roller. The grinding mechanism has a heat dissipation effect.

A fertilizer grinding mechanism, a water and fertilizer mixing device, and an aqueous fertilizer solution preparation production line. A fertilizer receiving body, where an edge is provided with a arranged first channel; a connecting body, fixed to a bottom of the fertilizer receiving body and provided with a second channel with the first channel, a bottom of the second channel is communicated with a buffer bin, a pushing block is arranged in the buffer bin, and the pushing block is connected with a drive mechanism for driving the block to move in direction of the body; and an inner grinding block, where the block is fixed to a bottom of the connecting body, an outer side of the inner grinding block is with a vertically movable grinding roller, the pushing block can push fertilizer under vertical movement of the roller. The grinding mechanism has a heat dissipation effect.

A waste management system, primarily intended to be for waste floating in water, though it can also be used on land. A shredding device will reduce the size of the particles of waste. Ocean water is removed by a drying device. The dried waste material is cryogenically frozen using liquid nitrogen or other suitable means. The frozen waste material is then pulverized and ground into a powder. The powder may then be sprayed into a gas-filled chamber and heated. Temperature, pressure and humidity are maintained within the chamber for more than one minute. Microwave or other radiation and catalysts may be used to enhance the process of extraction. The processed material is then removed from the chamber. Carbon and water may be recycled. The carbon may be used as fuel by the ship. Water may also be used by the ship or returned to the ocean in a non-toxic condition.