B03C1/002

Centrifuge for separating a sample into at least two components

The invention relates to a centrifuge for separating a sample into at least two components, comprising a chamber for receiving a sample to be centrifuged. According to the invention, the centrifuge further comprises a means for controlling the progress of the sample separation is located at the chamber.

In-line magnetic particle filter

A magnetic particle filter for a hydraulic control line is disclosed. A filter array is positioned to surround a portion of the hydraulic control line and includes alternating magnets and spacers having different interior diameters forming a ribbed interior surface. The corners between the spacers and magnets trap particles, magnetic and non-magnetic, thus removing them from the hydraulic control line.

SELF-CONTAINED DISPOSABLE TUBING SET FOR STERILE PREPARATION OF CELLS BY CULTURING, CENTRIFUGATION, AND COLUMN CHROMATOGRAPHY

The invention relates to a system, comprising: a) a sample processing unit, comprising an input port and an output port coupled to a rotating container having at least one sample chamber, the sample processing unit configured provide a first processing step to a sample or to rotate the container so as to apply a centrifugal force to a sample deposited in the chamber and separate at least a first component and a second component of the deposited sample; and b) a sample separation unit coupled to the output port of the sample processing unit, the cell separation unit comprising separation column holder (42), a pump (64) and a plurality of valves (1-11) configured to at least partially control fluid flow through a fluid circuitry and a separation column (40) positioned in the holder, the separation column configured to separate labeled and unlabeled components of sample flowed through the column.

System for separating a cell sample by centrifugation and column chromatography while maintaining sterility

The invention relates to a system, comprising: a) a sample processing unit, comprising an input port and an output port coupled to a rotating container having at least one sample chamber, the sample processing unit configured provide a first processing step to a sample or to rotate the container so as to apply a centrifugal force to a sample deposited in the chamber and separate at least a first component and a second component of the deposited sample; and b) a sample separation unit coupled to the output port of the sample processing unit, the cell separation unit comprising separation column holder (42), a pump (64) and a plurality of valves (1-11) configured to at least partially control fluid flow through a fluid circuitry and a separation column (40) positioned in the holder, the separation column configured to separate labeled and unlabeled components of sample flowed through the column.

Method for manufacturing a patient specific cell population using a multifunctional self-contained apparatus and tubing set

The invention relates to a system, comprising: a) a sample processing unit, comprising an input port and an output port coupled to a rotating container having at least one sample chamber, the sample processing unit configured provide a first processing step to a sample or to rotate the container so as to apply a centrifugal force to a sample deposited in the chamber and separate at least a first component and a second component of the deposited sample; and b) a sample separation unit coupled to the output port of the sample processing unit, the cell separation unit comprising separation column holder, a pump and a plurality of valves configured to at least partially control fluid flow through a fluid circuitry and a separation column positioned in the holder, the separation column configured to separate labeled and unlabeled components of sample flowed through the column.

HIGH-GRADIENT MAGNETIC FIELD FOR SUSTAINABLE TRANSITION METAL SEPARATION AND RECOVERY
20260115735 · 2026-04-30 ·

Systems and methods are provided for the transport and separation of transition metal solutes using magnetic fields. A high-gradient magnetic field can be generated between the flat-faced poles of an electromagnet. The magnetic separation process can be enhanced by the aggregation of paramagnetic metal solutes into clusters, which are predicted to be two orders of magnitude larger than individual solute units.