The present invention relates to method for chiral resolution of chiral species contained in a liquid placed in a cell formed by an inner wall and an outer wall surrounding the inner wall over at least a portion of the inner wall, each of the outer and inner walls being a solid of revolution about a longitudinal axis, the outer and inner walls being coaxial to one another, the method comprising: rotating the outer wall in one direction of rotation with respect to the inner wall for generating a Taylor-Couette flow within the liquid; collecting at least one of the chiral species.

The present invention also relates to a device therefor.

The present invention relates to method for chiral resolution of chiral species contained in a liquid placed in a cell formed by an inner wall and an outer wall surrounding the inner wall over at least a portion of the inner wall, each of the outer and inner walls being a solid of revolution about a longitudinal axis, the outer and inner walls being coaxial to one another, the method comprising: rotating the outer wall in one direction of rotation with respect to the inner wall for generating a Taylor-Couette flow within the liquid; collecting at least one of the chiral species.

The present invention also relates to a device therefor.

A novel Self-Locking Optoelectronic Tweezers (SLOT) for single microparticle manipulation across a large area is provided. DEP forces generated from ring-shape lateral phototransistors are utilized for locking single microparticles or cells in the dark state. The locked microparticles or cells can be selectively released by optically deactivating these locking sites.

Systems, methods, and devices are described herein for identifying, monitoring, isolating, or selecting a cell having a predefined characteristic in a mixed population of cells utilizing a combination of any one or more of iDEP, a region of localized field enhancement, a variable frequency electric field, a wide bandwidth amplifier, and/or an imaging apparatus.

The object of the present invention is to provide a separation method and a separation apparatus for carbon nanotubes capable of separating a mixture of carbon nanotubes in a highly efficient, inexpensive and simple manner. The present invention relates to a carbon nanotube separation method comprising: a step of preparing a dispersion liquid including a mixture of two or more types of carbon nanotubes having different zeta potentials; a step of introducing the dispersion liquid into a flow path formed between a first electrode having holes for allowing the dispersion liquid to pass therethrough, and a second electrode arranged so as to face the first electrode; a step of applying a DC voltage to the first electrode and the second electrode while the dispersion liquid is flowing through the flow path; and, a step of continuously collecting a dispersion liquid including carbon nanotubes separated to a first electrode side upon application of the voltage from an opposite side to the flow path with respect to the first electrode, and at the same time, continuously collecting a dispersion liquid including carbon nanotubes separated to a second electrode side from a downstream side of the flow path.

The object of the present invention is to provide a separation method and a separation apparatus for carbon nanotubes capable of separating a mixture of carbon nanotubes in a highly efficient, inexpensive and simple manner. The present invention relates to a carbon nanotube separation method comprising: a step of preparing a dispersion liquid including a mixture of two or more types of carbon nanotubes having different zeta potentials; a step of introducing the dispersion liquid into a flow path formed between a first electrode having holes for allowing the dispersion liquid to pass therethrough, and a second electrode arranged so as to face the first electrode; a step of applying a DC voltage to the first electrode and the second electrode while the dispersion liquid is flowing through the flow path; and, a step of continuously collecting a dispersion liquid including carbon nanotubes separated to a first electrode side upon application of the voltage from an opposite side to the flow path with respect to the first electrode, and at the same time, continuously collecting a dispersion liquid including carbon nanotubes separated to a second electrode side from a downstream side of the flow path.

Method and apparatus for the manipulation and/or control of the position of particles using time-variable fields of force; the fields of force can be of dielectrophoresis (positive or negative), electrophoresis, electrohydrodynamic or electrowetting on dielectric, possessing a set of stable points of equilibrium for the particles.

A 3-dimensional PDMS cell sorter having multiple passages in a PDMS layer that follow the same path in a DEP separation region and that are in fluid communication with each other within that region. The passages may differ in width transverse to the flow direction within the passages. Flat plates may sandwich the PDMS layer; each plate may have a planar electrode used to generate a DEP field within a sample fluid flowed within the passages. The DEP field may concentrate target cells or particulates within one of the passages within the DEP separation region. The passages may diverge after the DEP-separation region, leaving one passage with a high concentration of target cells or particulates. Techniques for manufacturing such structures, as well as other micro-fluidic structures, are also provided.

An inverted microwell provides rapid and efficient microanalysis system and method for screening of biological particles, particularly functional analysis of cells on a single cell basis. The use of an inverted open microwell system permits identification of particles, cells, and biomolecules that may be combined to produce a desired functional effect also functional screening of secreted antibody therapeutic activity as well as the potential to recover cells and fluid, and optionally expand cells, such as antibody secreting cells, within the same microwell.

A centrifugal liquid separating system broadly comprises an insert cartridge including a housing, an inlet, one or more flow guides, a stator, a compression nozzle, an expansion nozzle, and an outlet. The flow guides guide liquid flowing into the inlet past the stator into the compression nozzle. The stator induces a rotational vortex into the liquid flow. Liquid with heavier particles in the liquid flow is urged to the outside of the rotational vortex. Liquid with lighter particles and cleaner liquid is urged to the inside of the rotational vortex. The compression nozzle and the expansion nozzle are aligned to cooperatively form an annular liquid channel. The liquid with the heavier particles flows through the annular liquid channel and the liquid with the lighter particles and the cleaner liquid flows to the expansion nozzle to the outlet.