Disclosed herein is a novel method to fabricate magnetic silica nanomembranes using thin polymer cores based on silica deposition and self-wrinkling induced by thermal shrinkage. These micro- and nano-scale structures have vastly enlarged the specific area of silica, thus the magnetic silica nanomembranes can be used for solid phase extraction of nucleic acids. The magnetic silica nanomembranes are suitable for nucleic acid purification and isolation and demonstrated better performance than commercial particles in terms of nucleic acid recovery yield and integrity. In addition, the magnetic silica nanomembranes may have high nucleic acid capacity due to significantly enlarged specific surface area of silica. Methods of use and devices comprising the magnetic silica nanomembranes are also provided herein.

A fluidic device includes a first circulation flow path and a second circulation flow path which circulate a solution containing a sample material, the first circulation flow path and the second circulation flow path share at least a part of the flow path, and at least one selected from the group consisting of a capture unit which captures the sample material, a detection unit which detects the sample material, a valve, and a pump is provided on the shared flow path.

A process. The process includes forming a slurry comprising electrode active material particles of one or more lithium-ion electrochemical cells, magnetizing the electrode active material particles and separating the magnetized electrode active material particles from the slurry.

Magnetic cell levitation and cell monitoring systems and methods are disclosed. A method for separating a heterogeneous population of cells is performed by placing a microcapillary channel containing the heterogeneous population of cells in a magnetically-responsive medium in the disclosed levitation system and separating the cells by balancing magnetic and corrected gravitational forces on the individual cells. A levitation system is also disclosed, having a microscope on which the microcapillary channel is placed and a set of two magnets between which the microcapillary channel is placed. Additionally, a method for monitoring cellular processes in real-time using the levitation system is disclosed.

An apparatus for processing magnetic particles comprises a sealed enclosure and a magnetic field source. The sealed enclosure comprises an inlet into the enclosure and an outlet from the enclosure. The configuration of the sealed enclosure and of the inlet and the outlet are such that fluid containing the magnetic particles that is introduced into the enclosure through the inlet exhibits a spiral flow towards the outlet. The magnetic field source is disposed to the enclosure to intermittently apply a magnetic field to the fluid contained therein.

Provided herein are apparatus for independently manipulating the temperature of a plurality of reaction vessels, e.g., for automated processing of nucleic acids present in the vessels. Printed circuit boards (PCBs) comprising a mount area arranged to have mounted thereon a through-hole thermoelectric device (TED) to facilitate independent temperature control of reaction vessels are also provided, as well as methods relating to the same.

A magnetic assembly for use in a device for conducting assays is disclosed. The magnetic assembly comprises a pole piece having a longitudinal shaft interposed between at least two magnetic elements, each of the at least two magnetic elements having a north magnetic pole and a south magnetic pole; the at least two magnetic elements being orientated such that each north magnetic pole or each south magnetic pole is aligned inwardly towards the shaft; and wherein the pole piece comprises a cap at one end of the shaft which extends at least partially over a lateral surface of each of the at least two magnetic elements. Also disclosed is a device for conducting assays and a method of operating the device.

An apparatus for processing magnetite iron ore, including an upstream cyclone and a mill for grinding particles, wherein the upstream cyclone is arranged to operate as a splitter by diverting material in an overflow of the upstream cyclone to bypass the mill and by feeding material in an underflow of the upstream cyclone to the mill.

A pipeline strainer having a body with a straining element therein. One or more magnets are removably inserted into the straining element and configured to be removed from the body without causing liquid within the cavity to drain from the pipeline strainer. A drywell is used to house the magnets. The movement of withdrawing the magnets pulls metal particles along the outer surface of the drywell toward a debris drain. A baffle is disposed at the end of the drywell that is adjacent or near the debris drain to reduce turbulence from the fluid flow within the pipeline strainer.

The present disclosure provides devices, systems, and methods related to protein bioelectronics. In particular, the present disclosure provides devices, systems, and methods for manipulating a protein-of-interest into a target position within two electrodes in order to generate a functional bioelectronic circuit. The present disclosure also provides devices, systems, and methods for selectively attracting and concentrating one or more target analytes to the protein-of-interest, which can be used to develop analytical platforms to detect and measure various characteristics of protein function.