Devices and methods for immunomagnetic separation having a flexible inflatable processing chamber and magnetic array.

The invention relates to a method for the chip-removing production or machining of a workpiece by means of a tool, in which method a liquid, which mixes and accumulates with the chips produced during the machining process, is used for lubricating and/or cooling the machining process, and the chips are discharged from the accumulation counter to the downhill force along a discharge path by means of a magnetic force, wherein a return flow of the liquid carried by the discharged chips occurs due to the downhill force, and the return flow is deflected out of the discharge path and/or the discharge path has at least one point at which the supporting surface is temporarily withdrawn from the discharged chips.

Disclosed herein are reagents, compositions and methods for isolating and detecting rare cells such as circulating multiple myeloma cells as well as method of evaluating and treating patients suspected of having diseases of abnormal plasma cells, such as multiple myeloma.

An apparatus, vortex generator assembly and method for automated cell lysis and nucleic acid purification and processing. The vortex generator assembly includes sample holder having a lysis well, at least one wash well, and an elution well. The vortex generator assembly also includes a sample holder cover having a plurality of vibration rods for creating a vortex in the wells of the sample holder. The apparatus includes motor operating a rotating cam to cause the vibration rods to vibrate and create the vortex in a well holding fluid and magnetic beads, wherein the vortexing speed is sufficient to overcome the magnetic attraction between the beads and disperse the beads in solution, to collect nucleic acids such as DNA.

A filter is used for removing metallic contaminants in a solvent used in microcircuit fabrication. The filter includes a filter housing including a filter membrane for filtering solvent including metallic contaminants, and a magnet arranged about the filter housing and configured to generate a magnetic field to attract the metallic contaminants prior to the metallic contaminants entering the filter membrane. The magnet is arranged such that the magnetic field of the magnet is greater in a periphery of the filter housing compared to a central portion of the filter housing.

The present invention relates to a magnet plate for use in isolating a macromolecule from a mixture in a vessel, wherein the magnet plate has a reversible compression lock. The reversible compression lock engages the top plate and the base plate, wherein when in a locked position, the top plate is fixed and cannot move up and down, along the axis of the support or corner post and when in an unlocked position, the top plate is movable up and down along the axis of the support.

An integrated nucleic acid processing apparatus includes a first operation area, a second operation area and a separation wall. The first operation area includes multiple carrying boards for placing objects and reagents for processing nucleic acids in samples, and multiple operation modules for performing operations of nucleic acid processing. The second operation area includes two extraction regions for respectively performing nucleic acid extractions. The separation wall separates the first operation area from the second operation area and includes two openable door sheets spatially corresponding to the two extraction regions. Nucleic acid extraction plates can be moved from the first operation area to the second operation area by means of the carrying boards as the two openable door sheets are opened, and be isolated in the second operation area for performing nucleic acid extractions as the two openable door sheets are closed.

The present disclosure describes a filtration device that includes a housing that includes a first tubular section connected to a second tubular section, wherein the first tubular section extends along a longitudinal axis and includes an open end that forms a fluid inlet of the housing, a closed end opposite the open end, and a connection opening positioned between the open and closed ends, and wherein the second tubular section includes a first open end connected to the connection opening of the first tubular section and a second open end that forms a fluid outlet of the housing; and a filter that is arranged inside of the first tubular section and that extends along the longitudinal axis of the first tubular section; wherein the filter includes an electromagnet configured to generate a magnetic field that surrounds at least the first tubular section and attracts metal contaminants in a fluid to the filter. A filter system is also described.

A magnetite level monitoring device for a magnetic filter in a central heating system, the magnetic filter including a separation chamber, an inlet to the chamber and an outlet from the chamber, and a magnetic element disposed within the chamber for attracting magnetic particles and removing the magnetic particles from the system water as it flows through the chamber, and the monitoring device including: a housing for placing adjacent to the outside of the separation chamber; a magnetometer mounted to the housing; a magnetic field guide mounted to the housing, the magnetic field guide being disposed between the magnetometer and the outside of the separation chamber, when the housing is mounted to the separation chamber; and output means adapted to issue a notification when the output from the magnetometer exceeds a predetermined threshold.

A microfluidic device, a microfluidic detection assembly and a detection method for the microfluidic device. The microfluidic device includes a first substrate and a second substrate; the first substrate and the second substrate are oppositely arranged to define a channel between the first substrate and the second substrate, the channel is configured for liquid to flow, the first substrate includes a base substrate and a plurality of control assemblies which are arranged on the base substrate along an extending direction of the channel, each of the plurality of control assemblies includes: a first electrode, a second electrode and a plurality of coils, and the first electrode is configured to input currents into the plurality of coils, and the plurality of coils are connected in parallel to the second electrode.