B03C2201/18

Spinning vessel systems and methods for mixing, suspending particulates, aliquoting, washing magnetic beads, and concentrating analytes

Provided herein are apparatuses and systems for mixing liquids and suspensions that include vessels with structures that improve mixing while not contacting liquid delivery components. The apparatuses and systems can include a motor drive that allows speed and directional control of rotation of the vessel. The apparatuses and systems can include one or more magnets for separating magnetic beads in a suspension. Also provided are methods using said apparatuses and systems for mixing and separation processes.

WASTE OIL PURIFICATION APPARATUS
20230104542 · 2023-04-06 ·

Disclosed herein is a waste oil purification apparatus that purifies waste lubricating oil and waste oil at high speed by a precipitation induction method in a vacuum state and further completely removes metallic foreign materials, thereby improving the efficiency of the purification of waste oil. The waste oil purification apparatus may include a purifier configured to purify waste oil such as waste lubricating oil or general waste oil by a filtering method, and a separator configured to separate and remove foreign materials contained in the waste oil purified by the purifier.

MAGNETIC PARTICLE MANIPULATING APPARATUS

A magnetic particle manipulating apparatus includes a magnetic force source moving mechanism, an operation controller configured to control operation of the magnetic source moving mechanism, an openable cover for covering the device holder, a pressing mechanism provided on the cover to press the tubular device held by the device holder when the cover is closed so that warpage of the tubular device is corrected, an open/close state detector provided so as to detect an open/close state of the cover. The operation controller is configured to execute the processing operation only in a case where the open/close state detector detects that the cover is closed.

Separation device and separation method

A separation device includes: a container that includes a storage portion for storing liquid containing magnetic particles; and a coil that separates the magnetic particles from the liquid by generating a magnetic field through application of current, causing a magnetic force to act on the magnetic particles in a state where the coil stops with respect to the storage portion, and causing the magnetic particles to move from the storage portion against gravity acting on the liquid containing the magnetic particles.

PURIFICATION APPARATUS AND PURIFICATION METHOD
20220314234 · 2022-10-06 ·

A purification apparatus includes a holding unit including a bottom plate for supporting a bottom portion of a container to be mounted, and a magnetic unit arranged on the bottom plate or below the bottom plate so as to face the bottom portion of the container. The magnetic unit fixes magnetic particles of an amorphous metal to an inner bottom portion or an inner wall of the container so as to separate a liquid in the container and the magnetic particles contained in the liquid from each other and/or to collect the liquid while leaving the magnetic particles in the container.

DEVICE, ASSEMBLY AND METHOD FOR SEPARATING TRAMP METALS FROM LIQUID RAW MATERIALS

A device for separating tramp metals from liquid raw materials includes a body unit, a holding unit, a magnetic unit, a rinsing unit, and a driving unit. The body unit includes a tank for feeding-in and feeding-out liquid raw materials. The holding unit is coupled to the tank and includes and a plurality of non-magnetic holders received in the tank. The magnetic unit is mounted on the tank and includes an enclosure haying a telescopic wall to be in a compressed or extended state. The rinsing unit is fixed on the interior of the tank to rinse the non-magnetic holders. The driving unit is coupled the tank and the magnetic unit for driving the magnet unit moving between a first and second positions. An assembly is assembled from the device. And a method is carried out by the device or the assembly.

MAGNETIC TOOL AND CLEANING METHOD
20230144265 · 2023-05-11 ·

A magnetic tool may be provided with a ditch magnet that may include end plates (or handles) having a mostly open architecture, and these end plates may be permanently affixed to the ends of the magnetic bar. Ferrous metal may pass through by urging captured ferrous metal from one end of the ditch magnet to the opposite end. The captured ferrous metal may be urged from one end of the ditch magnet bar to an opposite end using a composite, multi-component wiper. The wiper may remove captured ferrous metal safely and effectively from the ditch magnet bar.

Methods for selection and generation of genome edited T cells

Methods are described herein for isolating clonal populations of T cells having a defined genetic modification. The methods are performed, at least in part, in a microfluidic device comprising one or more sequestration pens. The methods include the steps of: maintaining individual T cells (or precursors thereof) that have undergone a genomic editing process in corresponding sequestration pens of a microfluidic device; expanding the T cells into respective clonal populations of T cells; detecting, in one or more T cells of each clonal population, the absence of a cell surface marker that was present in the individual T cells (or precursors thereof); and detecting, in one or more T cells of each clonal population, the presence of a first nucleic acid sequence that is indicative of the presence of an on-target genome edit in the clonal population of T cells. Also described are compositions comprising one or more clonal populations of T cells isolated according to the methods disclosed herein.

ELECTROMAGNETIC ASSEMBLIES FOR PROCESSING FLUIDS

The disclosure relates to methods and apparatus for processing fluids through the use of a magnetic assembly wherein the magnetic assembly includes at least one fluid chamber containing a fluid and magnetic particles.

METHOD AND FLOW CELL FOR SEPARATING BIOMOLECULES FROM LIQUID MEDIUM

The present invention relates to a method for separating biomolecules from a liquid medium. The method comprises adding magnetic nanoparticles to the liquid medium comprising the biomolecules, the biomolecules each adapted to bind to respective surfaces of the magnetic nanoparticles; bringing the liquid medium to which the magnetic nanoparticles have been added into contact with a collector; applying a magnetic field to the liquid medium in contact with the collector to attract the magnetic nanoparticles ound with the biomolecules to a surface of the collector; and applying an electric potential to the surface of the collector to release the biomolecules from the magnetic nanoparticles.