B03C2201/26

DEVICE FOR COLLECTING AND ANALYZING AIRBORNE PARTICLES

A device for collecting particles present in a gas or gas mixture, including a component, a collection zone disposed on the component, on which said particles are deposited, collection device configured to force said particles to be deposited against the collection zone, a fluidic elution circuit arranged in said component to elute the particles present in the collection zone.

DEVICES, METHODS, AND SYSTEMS FOR MANIPULATING PROTEINS IN BIOELECTRONIC CIRCUITS
20220196596 · 2022-06-23 · ·

The present disclosure provides devices, systems, and methods related to protein bioelectronics. In particular, the present disclosure provides devices, systems, and methods for manipulating a protein-of-interest into a target position within two electrodes in order to generate a functional bioelectronic circuit. The present disclosure also provides devices, systems, and methods for selectively attracting and concentrating one or more target analytes to the protein-of-interest, which can be used to develop analytical platforms to detect and measure various characteristics of protein function.

Dielectrophoresis separators with cell ejection devices

A microfluidic device may, in an example, include at least one microfluidic channel, a dielectrophoresis separator to separate a plurality of cells passing within the at least one microfluidic channel, and a thermal resistor to eject at least one cell from the microfluidic device. A cassette may, in an example, include a die coupled to a substrate of the cassette, the die including at least one microfluidic channel, a dielectrophoresis separator along the microfluidic channel to separate a plurality of cells passing within the microfluidic channel, and an ejection device to eject at least one of the plurality of cells into an assay well.

METHOD AND APPARATUS FOR ISOLATING DESIRED CELLS FROM SUSPENSIONS WITH NON-MAGNETIC BIOLOGICAL MATERIALS
20220184634 · 2022-06-16 ·

The present invention concern a method and a device for the isolation of non-magnetic cells from a heterogeneous sample solution containing biological material including desired and undesired cells. The method comprises the steps of: —adding magnetic or magnetizable particles to the sample, wherein said particles have sizes in a range from 100 nm to 4 μm and exhibit surface components which support specific association with target cells, wherein said target cells comprise are either said desired or said undesired cells; —decreasing said external magnetic field gradient; —incubating said sample solution with said magnetic particles to obtain a magnetized cell fraction; —washing said magnetized cell fraction using a washing solution to reduce non-specific binding; —increasing said external magnetic field gradient; —separating said magnetized cell fractionation of target cells from said sample; wherein said sample solution is subjected to an external magnetic field gradient throughout said adding, incubating, washing and separating steps, and wherein said sample solution is rotated at least during said adding, incubating and washing steps.

METHOD FOR TRAPPING MICROPARTICLE AND MICROPARTICLE TRAPPING DEVICE

A microparticle trapping device includes: a fluid channel configured to be injected with a fluid including a microparticle; first and second electrodes configured to generate an electric field in the fluid channel; and an electrical insulator formed with at least one opening between the first and second electrodes in the fluid channel. The electrical insulator is disposed between the first and second electrodes so that an inhomogeneous electric field is made through the at least one opening between the first and second electrodes in the fluid channel, and the still other aspect is configured to trap the microparticle through dielectrophoresis.

System and method for determining dielectrophoresis crossover frequencies

The present invention provides a new method for accurately identifying DEP cross-over frequencies of one or more particles in a sample, and quickly and efficiently conveying that information to assist in the separation, e.g., DEP separation, or analysis of the one of more particles under examination or investigation. The present invention also provides an apparatus and method for monitoring the dielectrophoretic response of one or more particles and determining the DEP cross-over frequency of particles of interest.

ELECTROSTATIC PRECIPITATOR

An electrostatic precipitator for introducing sub-millimeter sized particles into a carrier material. The carrier material has a melting point which lies above 0° C., preferably above room temperature. The electrostatic precipitator comprises a casing having an inlet for inserting a gas flow into the casing and having an outlet for guiding a gas flow out of the casing. A channel for passing the gas flow from the inlet to the outlet is provided. A discharge electrode is provided on a first side of the channel. A collecting electrode is provided at a second side of at least a part of the channel. The electrostatic precipitator applies an electric field between the discharge electrode and the collecting electrode. A receiving volume is provided with a molten material as carrier material.

(1→3)-β-d-glucan as a measure of active mold
11353449 · 2022-06-07 · ·

Electrokinetic devices and methods are described with the purpose of collecting assayable agents from a dielectric fluid medium. Electrokinetic flow may be induced by the use of plasma generation at high voltage electrodes and consequent transport of charged particles in an electric voltage gradient. Actively growing mold releases the carbohydrate cell wall component (1.fwdarw.3)-β-D-Glucan into the air. The invention recognizes that the airborne fraction is that which affects respiratory health and selectively tests for a free form which is soluble in aqueous medium. The sample to be analysed is preferably collected by the electrokinetic propulsion method described, but any air sampling method such as filtration, impactor or impingement may be applicable.

MULTI-MICROORGANISM DETECTION SYSTEM

The present invention relates to a multi-microorganism detection system, and more particularly, to a multi-microorganism detection system using a dielectrophoresis force. Provided is a rapid and accurate multi-microorganism detection system. Microorganisms are concentrated at a high throughput using DEP after synthesizing the microorganisms and fluorescent magnetic particles, and when a complex in which the fluorescent magnetic particles are bound to the microorganisms passes through a detection unit by moving only the microorganisms to the detection unit after separating the magnetic particles from the complex (i.e., the microorganisms to which the magnetic particles are bound) using a DEP force, a fluorescence signal of a specific wavelength band is generated according to the type of the fluorescent magnetic particle and the concentration of the microorganisms according to the type of microorganism is measured by measuring and analyzing the fluorescence signal.

Magnetic Particle Separation System with Flexible Bioprocessing Container
20220162531 · 2022-05-26 ·

A magnetic particle separation system includes a magnetic field generating device having an upper surface with a receiving area formed thereon; and a magnetic field generating element disposed beneath the upper surface, the magnetic field generating element being configured to produce a magnetic field above the upper surface. A container assembly is disposed on the upper surface and includes: a flexible container having an outer wall with an interior surface that at least partially bounds an internal compartment, the outer wall having a front side and an opposing back side with the internal compartment disposed therebetween; a fluid inlet extending through the outer wall at the front side; a fluid outlet extending through the outer wall at the front side; and a first partition projecting into the internal compartment from the front side between the fluid inlet and the fluid outlet.