An exchangeable separation insert for a centrifugal separator includes a rotor casing enclosing a separation space in which a stack of separation discs is arranged, and first and second stationary portions. A feed inlet supplies a fluid mixture to the separation space. The insert includes a light phase outlet and a heavy phase outlet. The feed inlet is arranged at a first axial end of the rotor casing. One of the light phase outlet and heavy phase outlet is arranged at a second axial end. A first rotatable seal seals and connects the feed inlet and a second rotatable seal seals and connects one of the light phase outlet and heavy phase outlet.

A screw centrifuge has a rotating, cylindrical drum (11) with openings (14,15) for discharge of settleable solids (16), floating solids (17), and separating liquid (18). A rotatable shaft (12) has openings (22) for infeed of the solids to be separated, and two sections of screw flights (13,13′,13″,23,23′) working in opposite directions. A baffle disc (20) is arranged on the shaft between the infeed opening (22) and the discharge opening (14) for the settleable solids (16). The flight (13′,13″) of the screw for the settleable solids (16) surrounds the flight (23,23′) of the screw for the floating solids (17), and also work in opposite directions. The screw section for the floating solids (17) is designed as a multi-channel screw. The outer flight (13′,13″) of the screw for the settleable solids (16) can also have several channels.

A screw centrifuge has a rotating, cylindrical drum (11) with openings (14,15) for discharge of settleable solids (16), floating solids (17), and separating liquid (18). A rotatable shaft (12) has openings (22) for infeed of the solids to be separated, and two sections of screw flights (13,13′,13″,23,23′) working in opposite directions. A baffle disc (20) is arranged on the shaft between the infeed opening (22) and the discharge opening (14) for the settleable solids (16). The flight (13′,13″) of the screw for the settleable solids (16) surrounds the flight (23,23′) of the screw for the floating solids (17), and also work in opposite directions. The screw section for the floating solids (17) is designed as a multi-channel screw. The outer flight (13′,13″) of the screw for the settleable solids (16) can also have several channels.

Methods and systems for reducing bacterial contamination of platelets are disclosed. The methods and systems disclosed herein provide for the processing of a pre-determined volume of whole blood so as to reduce the risk that platelets separated and collected from the whole blood have a reduced risk of bacterial contamination.

Methods and systems for reducing bacterial contamination of platelets are disclosed. The methods and systems disclosed herein provide for the processing of a pre-determined volume of whole blood so as to reduce the risk that platelets separated and collected from the whole blood have a reduced risk of bacterial contamination.

In order to prevent air from being sucked into the separation chamber (12) of a counter-current type of centrifugal separator through the liquid outlet (24) thereof during the normal operation the separator a liquid trap in form of a well (28) is provided in the bottom of the separator housing (10). An outlet conduit (32) opens into the lower part of the well (28), wherein the well (28), at least in its upper part, has a substantially larger cross-sectional area than that of the outlet conduit (32).

In order to prevent air from being sucked into the separation chamber (12) of a counter-current type of centrifugal separator through the liquid outlet (24) thereof during the normal operation the separator a liquid trap in form of a well (28) is provided in the bottom of the separator housing (10). An outlet conduit (32) opens into the lower part of the well (28), wherein the well (28), at least in its upper part, has a substantially larger cross-sectional area than that of the outlet conduit (32).

A blood component separation device for separating a plurality of blood components from blood sampled from a blood donor, and collecting platelets, includes: an donor calculation unit that calculates a predicted platelet recovery rate from a hematocrit value of the blood and a platelet concentration of the blood, and calculates a recommended processing amount of the blood recommended for collecting a target number of units of platelets on the basis of the calculated predicted platelet recovery rate, wherein the operating unit sets the predicted platelet recovery rate calculated from any the hematocrit value and any the platelet concentration to be smaller by a predetermined value α when the blood donor is female than that when the blood donor is male.

A blood component separation device for separating a plurality of blood components from blood sampled from a blood donor, and collecting platelets, includes: an donor calculation unit that calculates a predicted platelet recovery rate from a hematocrit value of the blood and a platelet concentration of the blood, and calculates a recommended processing amount of the blood recommended for collecting a target number of units of platelets on the basis of the calculated predicted platelet recovery rate, wherein the operating unit sets the predicted platelet recovery rate calculated from any the hematocrit value and any the platelet concentration to be smaller by a predetermined value α when the blood donor is female than that when the blood donor is male.

A centrifugal field-flow fractionation device capable of improving analysis performance and shortening analysis time is provided. A first channel 111 communicating with a channel member is formed on a rotational shaft 11 that rotates together with a rotor. A second channel 644 communicating with the first channel 111 is formed on a fixing portion 60 fixed in a state of facing the rotational shaft 11 along a rotational axis L. A mechanical seal 66 having a pair of seal rings 661 and 662 that come into contact with each other and a biasing member 663 is provided to attach one seal ring 661 to the rotational shaft 11 and the other seal ring 662 to the fixing portion 60. The biasing member 663 biases the pair of seal rings 661 and 662 in a direction in which the pair of seal rings come in contact with each other. Since the rotational shaft 11 can be rotated at a high speed and the liquid sample can be fed at a high pressure, the analysis performance can be improved and the analysis time can be shortened.