Patent classifications
B04B11/04
System and method for automated platelet wash
A method for washing platelets includes introducing anticoagulant into a platelet product container, drawing re-anticoagulated platelet product from the platelet product container, and introducing it into a centrifuge bowl. The centrifuge bowl separates the platelets from the supernatant in which they are suspended. The method then washes the platelets by introducing wash solution into the centrifuge bowl. As the wash solution is introduced into the bowl, it displaces the supernatant from the bowl and into a waste container. The method then introduces platelet additive solution into the centrifuge bowl, which displaces the wash solution from the centrifuge bowl and into the waste container and further wash the platelets. The method then repeatedly accelerates and decelerates the centrifuge bowl to resuspend the platelets in the platelet additive solution.
System and method for automated platelet wash
A method for washing platelets includes introducing anticoagulant into a platelet product container, drawing re-anticoagulated platelet product from the platelet product container, and introducing it into a centrifuge bowl. The centrifuge bowl separates the platelets from the supernatant in which they are suspended. The method then washes the platelets by introducing wash solution into the centrifuge bowl. As the wash solution is introduced into the bowl, it displaces the supernatant from the bowl and into a waste container. The method then introduces platelet additive solution into the centrifuge bowl, which displaces the wash solution from the centrifuge bowl and into the waste container and further wash the platelets. The method then repeatedly accelerates and decelerates the centrifuge bowl to resuspend the platelets in the platelet additive solution.
Closed loop extraction system
A closed loop extraction system for extracting desired components from raw plant matter and method of use is disclosed. The closed loop extraction system features a solvent source, a chill tank, a wash tank, a rinse tank, a centrifuge, and a feed tank all in fluid communication via a series of interconnected pump systems. The method of extracting the desired products from raw plant matter uses this system to perform the extraction with a reduced amount of solvent in an energy-efficient manner.
Closed loop extraction system
A closed loop extraction system for extracting desired components from raw plant matter and method of use is disclosed. The closed loop extraction system features a solvent source, a chill tank, a wash tank, a rinse tank, a centrifuge, and a feed tank all in fluid communication via a series of interconnected pump systems. The method of extracting the desired products from raw plant matter uses this system to perform the extraction with a reduced amount of solvent in an energy-efficient manner.
METHOD FOR MONITORING AND/OR REGULATING THE OPERATION OF A CENTRIFUGE
A method for monitoring, controlling, and/or regulating the operation of a centrifuge, in particular a separator, during the centrifugal processing of a product, in particular when clarifying a product and/or when separating a product into different liquid phases. The centrifuge has a drum which can be rotated by a drive spindle, a drum mounting, and a drive motor. Force measurements are performed using one or more force sensors and analyzed, and an output is provided in the event of a deviation from a specified behavior and/or the analyses are used for or during the control and/or regulation of the operation of the centrifuge.
METHOD FOR MONITORING AND/OR REGULATING THE OPERATION OF A CENTRIFUGE
A method for monitoring, controlling, and/or regulating the operation of a centrifuge, in particular a separator, during the centrifugal processing of a product, in particular when clarifying a product and/or when separating a product into different liquid phases. The centrifuge has a drum which can be rotated by a drive spindle, a drum mounting, and a drive motor. Force measurements are performed using one or more force sensors and analyzed, and an output is provided in the event of a deviation from a specified behavior and/or the analyses are used for or during the control and/or regulation of the operation of the centrifuge.
Single-use centrifuge containers for separating biological suspensions and methods of use
A method for separating a biological suspension includes dispensing a liquid suspension comprised of cells or microorganisms from a bioreactor or fermenter into a sterile compartment of a first bag assembly, the first bag assembly including a collapsible bag having of one or more sheets of flexible film. The compartment of the first bag assembly is sealed closed. The first bag assembly, either with or without a manifold fluid coupled therewith, is then rotated, such as by using a centrifuge, so that the liquid suspension separates within the compartment into a pellet comprised of the cells or microorganisms and a liquid supernatant.
Single-use centrifuge containers for separating biological suspensions and methods of use
A method for separating a biological suspension includes dispensing a liquid suspension comprised of cells or microorganisms from a bioreactor or fermenter into a sterile compartment of a first bag assembly, the first bag assembly including a collapsible bag having of one or more sheets of flexible film. The compartment of the first bag assembly is sealed closed. The first bag assembly, either with or without a manifold fluid coupled therewith, is then rotated, such as by using a centrifuge, so that the liquid suspension separates within the compartment into a pellet comprised of the cells or microorganisms and a liquid supernatant.
System for blood separation with gravity valve for controlling a side-tapped separation chamber
A disposable blood separation set and a centrifugal blood processing system comprising a blood processing chamber adapted to be mounted on a rotor of a centrifuge; a frustro-conical cell separation chamber in fluid communication with the processing chamber, the cell separation chamber having an inlet, a primary outlet and a side tap outlet adjacent the inlet. A valve that is responsive to centrifugal force (a “gravity” valve) selects between the outlet and the side tap outlet. The gravity valve is mounted on the rotor. When the rotor spins at high speed, the gravity valve may open the primary outlet and close the side tap outlet. When the rotor spins at a lower speed, the gravity valve may open the side tap outlet and close the primary outlet.
System for blood separation with gravity valve for controlling a side-tapped separation chamber
A disposable blood separation set and a centrifugal blood processing system comprising a blood processing chamber adapted to be mounted on a rotor of a centrifuge; a frustro-conical cell separation chamber in fluid communication with the processing chamber, the cell separation chamber having an inlet, a primary outlet and a side tap outlet adjacent the inlet. A valve that is responsive to centrifugal force (a “gravity” valve) selects between the outlet and the side tap outlet. The gravity valve is mounted on the rotor. When the rotor spins at high speed, the gravity valve may open the primary outlet and close the side tap outlet. When the rotor spins at a lower speed, the gravity valve may open the side tap outlet and close the primary outlet.