Patent classifications
B04B11/04
Blood component separator with slider for sealing
A blood component separator (1) includes a blood storage vessel (20) that includes a first storage part (21) and a second storage part (22), a slider (30) movable from the first storage part to the second storage part, and a flow path (40f) for communicating an inside and an outside of the storage vessel. When the slider is in the first storage part, the first storage part and the second storage part are in communication with each other. When the slider is inserted into the second storage part, a liquid-tight seal is formed between the slider and the inner peripheral surface of the second storage part and the communication between the first storage part and the second storage part is blocked by the slider. The slider is movable in the second storage part while maintaining the liquid-tight seal between the slider and the inner peripheral surface of the second storage part. As the slider enters the second storage part, the blood component in the second storage part is pushed out of the storage vessel through the flow path.
Blood component separator with slider for sealing
A blood component separator (1) includes a blood storage vessel (20) that includes a first storage part (21) and a second storage part (22), a slider (30) movable from the first storage part to the second storage part, and a flow path (40f) for communicating an inside and an outside of the storage vessel. When the slider is in the first storage part, the first storage part and the second storage part are in communication with each other. When the slider is inserted into the second storage part, a liquid-tight seal is formed between the slider and the inner peripheral surface of the second storage part and the communication between the first storage part and the second storage part is blocked by the slider. The slider is movable in the second storage part while maintaining the liquid-tight seal between the slider and the inner peripheral surface of the second storage part. As the slider enters the second storage part, the blood component in the second storage part is pushed out of the storage vessel through the flow path.
CENTRIFUGE
In a cell washing centrifuge for washing living cells such as blood cells, control of the remaining amount of a supernatant according to the related art greatly depends on controlling the rotation speed of a motor, and thus a highly accurate motor control part is required to prevent overshooting or the like. In place of the related art, an easy control method is required. In the discharging of a supernatant discharge by a centrifuge having a plurality of test tube holders that can radially swing through centrifugal force, a holding part using an electromagnet that can control the swinging of the test tube holders, and a cleaning liquid distribution element that supplies a cleaning liquid into a test tube, a first decanting operation ({circle around (3)}-1) is performed by rotating a rotor in the order of acceleration, settling, and deceleration in a state in which the agitating angle of the test tube is restricted and discharging the supernatant of the cleaning liquid from the test tube, and a second decanting operation ({circle around (3)}-2) is performed, at a time of a final decanting operation, by accelerating the rotor, releasing restriction on the agitating angle during the acceleration, and then decelerating the rotor.
CENTRIFUGE
In a cell washing centrifuge for washing living cells such as blood cells, control of the remaining amount of a supernatant according to the related art greatly depends on controlling the rotation speed of a motor, and thus a highly accurate motor control part is required to prevent overshooting or the like. In place of the related art, an easy control method is required. In the discharging of a supernatant discharge by a centrifuge having a plurality of test tube holders that can radially swing through centrifugal force, a holding part using an electromagnet that can control the swinging of the test tube holders, and a cleaning liquid distribution element that supplies a cleaning liquid into a test tube, a first decanting operation ({circle around (3)}-1) is performed by rotating a rotor in the order of acceleration, settling, and deceleration in a state in which the agitating angle of the test tube is restricted and discharging the supernatant of the cleaning liquid from the test tube, and a second decanting operation ({circle around (3)}-2) is performed, at a time of a final decanting operation, by accelerating the rotor, releasing restriction on the agitating angle during the acceleration, and then decelerating the rotor.
CENTRIFUGE SYSTEM FOR SEPARATING CELLS IN SUSPENSION
An apparatus for separating cell suspension material into centrate and concentrate, includes a single use structure (178, 240, 250) releasably positioned in a cavity in a solid wall rotatable centrifuge bowl (172). The bowl and portions of single use structure rotate about an axis (174). A stationary inlet feed tube (184), a centrate discharge tube (212) and a concentrate discharge tube (230) extend along the axis of the rotating single use structure. A centrate centripetal pump (208) is in fluid connection with the centrate discharge tube. A concentrate centripetal pump (216) is in fluid connection with the concentrate discharge tube. A controller (274) operates responsive to sensors (264, 270) in respective centrate and concentrate discharge lines (262, 268), to control flow rates of a concentrate pump (272) and a centrate pump (266) to produce output flows of cell concentrate and generally cell free centrate.
CENTRIFUGE SYSTEM FOR SEPARATING CELLS IN SUSPENSION
An apparatus for separating cell suspension material into centrate and concentrate, includes a single use structure (178, 240, 250) releasably positioned in a cavity in a solid wall rotatable centrifuge bowl (172). The bowl and portions of single use structure rotate about an axis (174). A stationary inlet feed tube (184), a centrate discharge tube (212) and a concentrate discharge tube (230) extend along the axis of the rotating single use structure. A centrate centripetal pump (208) is in fluid connection with the centrate discharge tube. A concentrate centripetal pump (216) is in fluid connection with the concentrate discharge tube. A controller (274) operates responsive to sensors (264, 270) in respective centrate and concentrate discharge lines (262, 268), to control flow rates of a concentrate pump (272) and a centrate pump (266) to produce output flows of cell concentrate and generally cell free centrate.
FULL-AUTOMATIC GENE ANALYSIS APPARATUS AND GENE ANALYSIS METHOD
The present disclosure provides a full-automatic gene analysis apparatus and a gene analysis method, and relates to the field of medical detection technologies. The apparatus includes a body, a first taking and placing device, a second taking and placing device, a first lid opening and closing device, a second lid opening and closing device, a sample rack, a consumable rack, a PCR detection device and a centrifugal transfer device. The first taking and placing device is configured to take and place a sample tube or a PCR tube or perform a pipetting operation, a lid is automatically opened and closed by the lid opening and closing device; automatic transfer and centrifuging operations of the PCR tube are realized by the centrifugal transfer device; a PCR detection step is automatically performed by the second taking and placing device and the PCR detection device.
FULL-AUTOMATIC GENE ANALYSIS APPARATUS AND GENE ANALYSIS METHOD
The present disclosure provides a full-automatic gene analysis apparatus and a gene analysis method, and relates to the field of medical detection technologies. The apparatus includes a body, a first taking and placing device, a second taking and placing device, a first lid opening and closing device, a second lid opening and closing device, a sample rack, a consumable rack, a PCR detection device and a centrifugal transfer device. The first taking and placing device is configured to take and place a sample tube or a PCR tube or perform a pipetting operation, a lid is automatically opened and closed by the lid opening and closing device; automatic transfer and centrifuging operations of the PCR tube are realized by the centrifugal transfer device; a PCR detection step is automatically performed by the second taking and placing device and the PCR detection device.
Arrangement for preparing a plurality of samples for an analytical method
The invention relates to an arrangement for preparing a plurality of samples for an analytical method, comprising a carousel with a solid housing and moveable receiving parts for the sample containers; a control for controlling the receiving parts in the carousel; and a sample receiving device for providing the sample for the analytical method. Said arrangement is characterized in that one or more stations for preparing samples are provided on the carousel, the receiving parts for the sample containers of the carousel can be positioned on said stations. Said arrangement also comprises a centrifuge with pairs of opposite lying receiving parts provided for the sample containers, and said receiving parts are arranged such that they can move on the centrifuge for the sample holder such that a transfer of a sample holder between a receiving part in the carousel and a receiving part in the centrifuge can be carried out. The control takes place by the same control which is also provided for controlling the carousel.
Blood washing and separation system
A blood washing system (20) having a rotor (22) defining an internal chamber for receiving a multi-component fluid and a skimmer assembly (24) including a moveable buoy (28) having an orifice (32) fluidly connected to an access port for the rotor for selectively withdrawing separated fractions of the multi-component fluid. The multi-component fluid can be fed into the internal chamber before the rotor (22) can be rotated at a first speed to fractionate the multi-component fluid. A brake can be applied to the rotor to slow rotation of the rotor to a slower second speed or stop rotation of the rotor causing the solid and denser fluid fractions to settle on the bottom wall (44) of the rotor (22). The buoy (28) can have a specific gravity corresponding to a selected fraction such that the buoy floats on a surface of the selected fraction, wherein the fractions floating on the selected fraction can be withdrawn through the orifice (32).