A method for analyzing particles in an air stream includes concentrating the particles in an interior region of the air stream and deflecting the concentrated particles in the air stream with a generated thermal gradient. Smaller particles in the air stream may be selectively deflected away from the interior region and towards a periphery of the air stream at a different rate than larger particles in the air stream. The generated thermal gradient may be controlled to deflect particles in a selected particle size range onto a surface of a particle detector. An effective mass of the collected particles and an aerosol mass concentration estimate of the particles within the selected particle size range may be generated. Systems for analyzing particles are also disclosed.

A method for analyzing particles includes concentrating the particles in an interior region of an air stream, generating a thermal gradient to deflect the concentrated particles from the interior region of the air stream to a peripheral region of the air stream, receiving orientation information, and adjusting the thermal gradient in response to the received orientation information. The particles may be concentrated in the interior of the air stream with at least two heater elements positioned near a periphery of the air stream and configured to cooperatively force particles away from the periphery and towards the interior region of the air stream. The orientation information may include gravity vector component information or angular rate component information in one, two or three substantially orthogonal directions relative to the air stream. Various systems for airborne particle detection with orientation-dependent particle discrimination are disclosed.

A system for analyzing particles in an air stream includes a first heater element configured to deflect particles in an interior region of the air stream towards a peripheral wall of an air channel encompassing the air stream, a second heater element controllable to deflect the particles in a first lateral direction along the peripheral wall, and a third heater element controllable to deflect the particles in a second lateral direction along the peripheral wall. Thermal gradients in the air channel generated by the heater elements may thermophoretically force particles towards the peripheral wall in a direction perpendicular to the air stream to allow thermophoretic forcing and scanning of particles in either the first lateral direction or the second lateral direction along the peripheral wall and onto a surface of a particle detector. Systems and methods for scanning particles with thermophoretic forces are disclosed.

A system for detecting and analyzing particles in an air stream includes an inlet, a particle concentrator and a particle discriminator having an air channel with a cross-sectional geometry that changes within at least one of the inlet, particle concentrator and particle discriminator. The system may have a sheath air stage including a port for providing sample air, at least one sheath air inlet port for providing sheath air, and a sheath air combining region. The system may include an airflow compression stage having a varying air channel that narrows as the air stream traverses the airflow compression stage to pre-concentrate particles within an interior region of the air stream. The system may include an airflow expansion stage having an air channel that widens to slow the airstream and particle velocities. A portion of the air channel height may be narrowed to allow a larger thermophoretic force to be generated.

An analytical laboratory system and method for processing samples is disclosed. A sample container is transported from an input area to a distribution area by a gripper comprising a means for inspecting a tube. An image is captured of the sample container. The image is analyzed to determine a sample container identification. A liquid level of the sample in the sample container is determined. A scheduling system determines a priority for processing the sample container based on the sample container identification. The sample container is transported from the distribution area to a subsequent processing module by the gripper.

Blood separation systems and methods are provided for controlling the interface between separated blood components. The system includes a centrifuge assembly having a light-transmissive portion, a light reflector, and a fluid processing region therebetween. An optical sensor system emits a scanning light beam along a path toward the light-transmissive portion, which transmits at least a portion of the scanning light beam to the fluid processing region and the light reflector. The light reflector reflects at least a portion of the scanning light beam toward the optical sensor system along a path substantially coaxial to the path of the scanning light beam from the optical sensor system toward the light-transmissive portion of the centrifuge assembly. The scanning light beam may be a white light beam or narrow spectrum beam. The reflected beam may be directed through the optical sensor system via optical fibers.

An optical monitoring system is provided for use with a blood processing system. The system includes a light source configured to illuminate a disposable flow circuit received in a centrifuge and a light detector configured to receive an image of the disposable flow circuit. A controller combines two or more of the images received by the light detector to generate a two-dimensional output. The output is used to control the separation of blood within the disposable flow circuit. The monitoring system may also be used to verify that the disposable flow circuit is suitable for use with the centrifuge or that the disposable flow circuit is properly aligned within the centrifuge. The monitoring system may be positioned outside of the centrifuge bucket which receives the centrifuge.

A continuous flow centrifuge bowl includes a rotatable outer body, and a top and bottom core that are rotatable with the outer body. The bottom core has a wall extending proximally from a bottom wall. The proximally extending wall is radially outward from at least a portion of the top core and, together with the top core, defines a primary separation region in which initial separation of the whole blood occurs. The bowl may also have a secondary separation region located between the top core and the outer body, and a rotary seal that couples an inlet port and two outlet ports to the outer body. The inlet port may be connected to an inlet tube that extends distally into a whole blood introduction region. Additionally, one of the outlet ports may be connected to an extraction tube that extends into a region below the bottom core.

A centrifugal separator apparatus for separating components of a fluid stream; the apparatus comprising a support structure and a centrifugal separator unit rotatably mounted on the support structure so as to be rotatable about a rotational axis extending through the centrifugal separator unit; a drive element for driving rotation of the centrifugal separator unit; wherein the centrifugal separator unit comprises a centrifugal separation chamber having an inlet which is connected or connectable to a source of fluid requiring separation, a first outlet for collecting a higher density component of the fluid stream, and a second outlet for collecting a lower density component of the fluid stream; the first outlet being connected or connectable to a first collector for collecting the higher density component and the second outlet being connected or connectable to a second collector for collecting the lower density component; the centrifugal separation chamber comprising a curved or inclined guide surface for guiding flow of the fluid from the inlet in a radially outward direction; wherein the centrifugal separator unit is provided with a wall member which is axially movable to provide a selected degree of occlusion of the first outlet and thereby control flow of the higher density component through the first outlet.

A system includes a centrifuge, a centrifuge feed pit, a centrifuge discharge pit, and a computer system. The centrifuge receives solids-laden drilling fluid via a centrifuge pump and discharges conditioned drilling fluid and separated solids using centrifuge operational parameters. The centrifuge feed pit comprises the solids-laden drilling fluid and a first solids content sensor. The centrifuge discharge pit comprises the conditioned drilling fluid and a second solids content sensor. The computer system is configured to analyze results from the first solids content sensor and the second solids content sensor using a set of goal drilling fluid parameters and send an instruction to the centrifuge based on the analyzed results of the solids content sensors. The instruction comprises a first instruction to stop the centrifuge or a second instruction to adjust the centrifuge operational parameters.