The present invention provides compositions and methods of treating and improving the symptoms of rheumatoid arthritis using an antibody or antigen-binding fragment thereof that specifically binds human interleukin-6 receptor (hIL-6R) with a DMARD.

This method for manufacturing a high-temperature component formed of a Ni-based alloy includes a step of subjecting a workpiece of the Ni-based alloy to hot die forging using predetermined dies to form a forge-molded article, the step including: a die/workpiece co-heating substep of heating the workpiece interposed between the dies to a forging temperature; and a hot forging substep of taking out the workpiece and the dies into a room temperature environment and immediately performing hot forging on the workpiece using a press machine. The predetermined dies are formed of another Ni-based superalloy comprising γ and γ′ phases, and have features in that: a solvus temperature of the γ′ phase is 1050-1250° C.; and the γ′ phase precipitates at least 10 vol. % at 1050° C. and has two kinds of forms of intra-grain γ′ phase precipitations within the γ phase grains and inter-grain γ′ phase precipitations between/among the γ phase grains.

The present disclosure relates to a steel forging process, in particular a hot steel forging process in horizontal press of a metal tube, preferably a cylindrical steel tube.

The present disclosure relates to a steel forging process, in particular a hot steel forging process in horizontal press of a metal tube, preferably a cylindrical steel tube.

A process of manufacturing of segment for carbon thrust bearing uses stainless-steel (SS) round bars/sheets/logs of suitable grade as raw material. The SS round bars/sheets/logs undergo cutting operation to cut into SS billets. The billets successively undergo heating and hot forging processes to form segments of desired shapes. Thereafter, the segment is subjected to heat treatment process i.e. stress relieving, hardening and tempering process successively for obtaining consistent and uniform grain structure, mechanical properties and physical properties of segments which are cost-effective in terms of lower maintenance and lower handling efforts. After heat-treatment process, segment undergoes surface-finishing processes i.e. grinding, lapping and polishing successively for obtaining mirror like surface finishing that gives greater anti-friction property and lower co-efficient of friction. The manufacturing process according to present invention yields consistent grain structure, refine, dense and uniform microstructure of segments which imparts optimum strength, ductility, toughness and resistance to impact and fatigue.

A process of manufacturing of segment for carbon thrust bearing uses stainless-steel (SS) round bars/sheets/logs of suitable grade as raw material. The SS round bars/sheets/logs undergo cutting operation to cut into SS billets. The billets successively undergo heating and hot forging processes to form segments of desired shapes. Thereafter, the segment is subjected to heat treatment process i.e. stress relieving, hardening and tempering process successively for obtaining consistent and uniform grain structure, mechanical properties and physical properties of segments which are cost-effective in terms of lower maintenance and lower handling efforts. After heat-treatment process, segment undergoes surface-finishing processes i.e. grinding, lapping and polishing successively for obtaining mirror like surface finishing that gives greater anti-friction property and lower co-efficient of friction. The manufacturing process according to present invention yields consistent grain structure, refine, dense and uniform microstructure of segments which imparts optimum strength, ductility, toughness and resistance to impact and fatigue.

Provided are a hollow drive shaft using an upsetting method and a method of manufacturing the same, in which hot forging and upsetting processes are applied to both ends of a workpiece so that an outer diameter at both ends of the workpiece is greater than an outer diameter of a middle part of the workpiece, thereby reducing a weight of the drive shaft and enabling the drive shaft to transmit higher driving power. According to the present invention, the upsetting process is applied during the hot forging process to manufacture the hollow drive shaft, portions to be substantially processed are limited to portions at both ends of the workpiece, and the number of upsetting processes is limited to a minimum number (2 or the like), such that initial investment costs and manufacturing costs are low because the number of processes is small.

Provided are a hollow drive shaft using an upsetting method and a method of manufacturing the same, in which hot forging and upsetting processes are applied to both ends of a workpiece so that an outer diameter at both ends of the workpiece is greater than an outer diameter of a middle part of the workpiece, thereby reducing a weight of the drive shaft and enabling the drive shaft to transmit higher driving power. According to the present invention, the upsetting process is applied during the hot forging process to manufacture the hollow drive shaft, portions to be substantially processed are limited to portions at both ends of the workpiece, and the number of upsetting processes is limited to a minimum number (2 or the like), such that initial investment costs and manufacturing costs are low because the number of processes is small.

A system for producing components by hot forming includes a pre-heat station, a furnace, and a press. The pre-heat station is configured to receive a blank; and to pre-heat at least a portion of the blank to a pre-heat temperature by thermal conduction. The furnace is constructed and arranged to receive the pre-heated blank from the pre-heat station and to heat the entire blank to a deformation temperature. The deformation temperature is higher than the pre-heat temperature. The press is constructed and arranged to receive the heated blank from the furnace and to form the heated blank into the shape of the component.

A method of forming a copper manganese sputtering target including subjecting a copper manganese billet to a first unidirectional forging step, heating the copper manganese billet to a temperature from about 650° C. to about 750° C., subjecting the copper manganese billet to a second unidirectional forging step, and heating the copper manganese billet to a temperature from about 500° C. to about 650° C. to form a copper alloy.