An axial cast hole is formed to have a large diameter side end on one side at a draft angle. A large diameter hole is formed on the one side to form a stepped surface between the large diameter hole and the axial cast hole. The stepped surface has an inner periphery end located on a plane perpendicular to the axial direction. A tool is moved from the one side toward the other side coaxially with the axial cast hole to make contact with the stepped surface. The tool is moved subsequently to cut the inner periphery of the axial cast hole between the large diameter hole and the first port. The tool is moved subsequently to cut the inner periphery of the axial cast hole on the other side relative to the first port.

A cast component includes a cast structure having a primary geometry formed by a mold. Also included is a structural deposit formed by cold spraying one or more layers of powdered material on an outer surface of the cast structure, the structural deposit defining at least one feature of the overall outer geometry of the cast component in addition to the primary geometry. Also provided are methods of manufacturing the cast component.

A cast component includes a cast structure having a primary geometry formed by a mold. Also included is a structural deposit formed by cold spraying one or more layers of powdered material on an outer surface of the cast structure, the structural deposit defining at least one feature of the overall outer geometry of the cast component in addition to the primary geometry. Also provided are methods of manufacturing the cast component.

Provided are a cancer cell-trapping metal filter which has a high opening ratio, a cancer cell-trapping metal filter sheet, a cancer cell-trapping device using the cancer cell-trapping filter, and manufacturing methods therefor.

According to a cancer cell-trapping metal filter 1, openings of connected through-holes 12 that are formed in a metal sheet 11 have a wave shape, and thus it is possible to extract a CTC from other components by utilizing a hole diameter on a short-side side of the openings, and it is possible to make the connected through-holes be closer to each other due to the wave shape while maintaining a CTC trapping ability. Accordingly, it is possible to further improve the opening ratio in the cancer cell-trapping metal filter 1.

The present disclosure generally relates to casting molds including a casting core comprising an outer shell mold surrounding at least a portion of a casting core and a casting core comprising a second metal skin layer around a first metal component. In one aspect, at least one portion of the first metal component may be exposed on a surface of the outer shell mold. In another aspect, the outer shell mold may be configured to define a cavity in the casting core when the first metal component is removed and the second metal skin layer is not removed.

The present disclosure generally relates to casting molds including a casting core comprising an outer shell mold surrounding at least a portion of a casting core and a casting core comprising a second metal skin layer around a first metal component. In one aspect, at least one portion of the first metal component may be exposed on a surface of the outer shell mold. In another aspect, the outer shell mold may be configured to define a cavity in the casting core when the first metal component is removed and the second metal skin layer is not removed.

The present disclosure generally relates to casting molds including a casting core comprising a first metal component and a second metal component. In an aspect, the first metal component has a lower melting point than the second metal component. In another aspect, the second metal component surrounds at least a portion of the first metal component and defines a cavity in the casting core when the first metal component is removed and the second metal component is not removed.

The present disclosure generally relates to casting molds including a casting core comprising a first metal component and a second metal component. In an aspect, the first metal component has a lower melting point than the second metal component. In another aspect, the second metal component surrounds at least a portion of the first metal component and defines a cavity in the casting core when the first metal component is removed and the second metal component is not removed.

Methods, structures, devices and systems are disclosed for fabricating and implementing nanoparticles with hollow core and sealable holes. In one aspect, a nanoparticle device can includes a shell structure including at least two layers including an internal layer and an external layer, the internal layer structured to enclose a hollow interior region and include one or more holes penetrating the internal layer, the external layer is of a porous material and formed around the internal layer and sealing the one or more holes, and a substance contained within the hollow interior region, the substance incapable of passing through the external layer.

Methods, structures, devices and systems are disclosed for fabricating and implementing nanoparticles with hollow core and sealable holes. In one aspect, a nanoparticle device can includes a shell structure including at least two layers including an internal layer and an external layer, the internal layer structured to enclose a hollow interior region and include one or more holes penetrating the internal layer, the external layer is of a porous material and formed around the internal layer and sealing the one or more holes, and a substance contained within the hollow interior region, the substance incapable of passing through the external layer.