The present invention relates to pharmaceutical dosage forms, for example to a tamper resistant dosage form including an opioid analgesic, and processes of manufacture, uses, and methods of treatment thereof.

The present invention relates to pharmaceutical dosage forms, for example to a tamper resistant dosage form including an opioid analgesic, and processes of manufacture, uses, and methods of treatment thereof.

The present invention relates to pharmaceutical dosage forms, for example to a tamper resistant dosage form including an opioid analgesic, and processes of manufacture, uses, and methods of treatment thereof.

A production method, containing the step of: mixing 0.02 to 0.6 parts by mass of an organic peroxide, 0.2 to 300 parts by mass of an inorganic filler, 2 to 15.0 parts by mass of a silane coupling agent, and a silanol condensation catalyst, based on 100 parts by mass of a polyolefin-based resin, in which the inorganic filler has an X value specified by Formula (I) satisfies 5 to 1050,

X=A/BFormula (I)

wherein, A denotes a total amount of a product of a BET specific surface area (m.sup.2/g) of the inorganic filler and a blending amount of the inorganic filler, and B denotes a blending amount of the silane coupling agent; and a crosslinkable resin composition and a crosslinked resin molded body produced by the production method; and a silane master batch and a molded article.

A production method, containing the step of: mixing 0.02 to 0.6 parts by mass of an organic peroxide, 0.2 to 300 parts by mass of an inorganic filler, 2 to 15.0 parts by mass of a silane coupling agent, and a silanol condensation catalyst, based on 100 parts by mass of a polyolefin-based resin, in which the inorganic filler has an X value specified by Formula (I) satisfies 5 to 1050,

X=A/BFormula (I)

wherein, A denotes a total amount of a product of a BET specific surface area (m.sup.2/g) of the inorganic filler and a blending amount of the inorganic filler, and B denotes a blending amount of the silane coupling agent; and a crosslinkable resin composition and a crosslinked resin molded body produced by the production method; and a silane master batch and a molded article.

A composite material including silanated filler and mixed polymerizable monomer, having a stable pasty property which keeps well and has a consistent usability. A composite material containing a silanated filler, a polymerizable monomer, and a polymerization initiator, and may be produced by a process which includes a mixed polymerizable monomer preparing step, a silanation step, a silanated filler preserving step, a composite material preparing step, a composite material preserving step, a composite material filling step, and a small quantity preserving container preserving step.

A composite material including silanated filler and mixed polymerizable monomer, having a stable pasty property which keeps well and has a consistent usability. A composite material containing a silanated filler, a polymerizable monomer, and a polymerization initiator, and may be produced by a process which includes a mixed polymerizable monomer preparing step, a silanation step, a silanated filler preserving step, a composite material preparing step, a composite material preserving step, a composite material filling step, and a small quantity preserving container preserving step.

A composite shoe sole having an outsole which is made of rubber, plastic or thermoplastic rubber (TPR), and a plurality of small pieces of fabrics filled inside the outsole; the outsole and the plurality of small pieces of fabrics are injection-molded and integrally formed. A method of making the composite shoe sole is also disclosed. The composite shoe sole allows the shoe sole to have good flex resistance when flexed thanks to the small pieces of fabrics filled inside the outsole. The small pieces of fabrics also provide good puncture resistance to the shoe sole, thus increasing the usage life of the shoe sole. Also, the shoe sole is lighter and cost is reduced. When transparent material is used for making the outsole, the small pieces of fabrics inside the outsole can render the whole shoe sole a visual effect different from conventional shoe soles.

A composite shoe sole having an outsole which is made of rubber, plastic or thermoplastic rubber (TPR), and a plurality of small pieces of fabrics filled inside the outsole; the outsole and the plurality of small pieces of fabrics are injection-molded and integrally formed. A method of making the composite shoe sole is also disclosed. The composite shoe sole allows the shoe sole to have good flex resistance when flexed thanks to the small pieces of fabrics filled inside the outsole. The small pieces of fabrics also provide good puncture resistance to the shoe sole, thus increasing the usage life of the shoe sole. Also, the shoe sole is lighter and cost is reduced. When transparent material is used for making the outsole, the small pieces of fabrics inside the outsole can render the whole shoe sole a visual effect different from conventional shoe soles.

The present invention is directed to plant fiber-reinforced biocomposite thermoplastic and/or resin compositions and a method for reinforcing thermoplastic resins. The present invention provides a use for the cellulose portion of a plant material, which is the portion left over after processing the selected plant materials to separate the cellulose in a mechanical process that does not damage the internal molecular structure of the cellulose fraction, enabling the cellulose fraction to chemically bond with the thermoplastic resin to enhance the reinforcement of the resin or thermoplastic biocomposite composition.