A transdermal drug delivery patch according to an exemplary embodiment of the present invention includes: a flexible base layer; and a plurality of microneedle disposed at one surface of the base layer. Each of the plurality of microneedles includes a biodegradable polymer and a drug and has an empty space inside. Each of the plurality of microneedles is formed as a star-shaped pyramid including a plurality of protrusions extending in a radial direction, and a part between two protrusions adjacent along the circumferential direction among the plurality of protrusions is concave.

A method and an apparatus of forming a three-dimensional object, wherein the method includes providing a carrier and an optically transparent member having a build surface, said carrier and said build surface defining a build region therebetween; filling said build region with a polymerizable liquid, continuously or intermittently irradiating said build region with light through said optically transparent member to form a solid polymer from said polymerizable liquid, continuously or intermittently advancing (e.g., sequentially or concurrently with said irradiating step) said carrier away from said build surface to form said three-dimensional object from said solid polymer, said optically transparent member comprising a build plate for a three-dimensional printer comprising: an optically transparent first channel layer; an optically transparent, gas permeable second channel layer on the first channel layer; and a flexible, optically transparent, gas-permeable sheet having an upper and lower surface, the sheet upper surface comprising a build surface for forming a three-dimensional object, the sheet lower surface being positioned on the second channel layer.

The present disclosure relates to a resin injector and oil compactor used to manufacture composite components by RTM and FIP processes. A resin injector comprising an automated resin degassing and charging/discharging station and an in-line heat exchanger. An oil compactor capable of applying a dynamic compaction at a desired frequency, nominal pressure and temperature to an FIP mold. A multi-injection equipment for manufacturing composite parts by RTM and FIP is provided. The multi-injection equipment includes 1 or more cylinder injectors for delivery liquid resin into an RTM or FIP mold cavity. An oil compactor equipment to work with FIP is provided. The oil compactor contains an oil container and a heat exchanger to maintain the oil at a desired temperature. The pre-heated oil is injected into the FIP under pressure after the resin injection to fulfill the impregnation of the fibrous strengthener and consolidate the composite part.

Molding methods and molds for making a synthetic resin molded product include disposing a curable liquid resin mixture in a recess of a female mold. The curable liquid resin mixture is then simultaneously agitated and degassed by a mixer while under a partial vacuum. More specifically, at least the female mold is orbited around an orbital axis while being rotated about a rotational axis that is eccentric to the orbital axis. After being thoroughly mixed and degassed, the liquid mixture is then cured in the mold unit.

A method of manufacturing bulked continuous carpet filament which, in various embodiments, comprises: (A) grinding recycled PET bottles into a group of flakes; (B) washing the flakes; (C) identifying and removing impurities, including impure flakes, from the group of flakes; (D) passing the group of flakes through an MRS extruder while maintaining the pressure within the MRS portion of the MRS extruder below about 1.5 millibars; (E) passing the resulting polymer melt through at least one filter having a micron rating of less than about 50 microns; and (F) forming the recycled polymer into bulked continuous carpet filament that consists essentially of recycled PET.

An apparatus and method for repairing a damaged laminate including the process of cutting out a damaged section and replacing damaged section with a repair laminate, then covering the repair laminate with a vacuum bag having a heater disposed therein. Thereafter, applying heat and pressure to the repair laminate with the heater and vacuum bag to adequately debulk and cure the repair laminate.

A method of manufacturing bulked continuous carpet filament which, in various embodiments, comprises: (A) grinding recycled PET bottles into a group of flakes; (B) washing the flakes; (C) identifying and removing impurities, including impure flakes, from the group of flakes; (D) passing the group of flakes through an MRS extruder while maintaining the pressure within the MRS portion of the MRS extruder below about 5 millibars; (E) passing the resulting polymer melt through at least one filter having a micron rating of less than about 50 microns; and (F) forming the recycled polymer into bulked continuous carpet filament that consists essentially of recycled PET.

A method of manufacturing bulked continuous carpet filament which, in various embodiments, comprises: (A) grinding recycled PET bottles into a group of flakes; (B) washing the flakes; (C) identifying and removing impurities, including impure flakes, from the group of flakes; (D) passing the group of flakes through an MRS extruder while maintaining the pressure within the MRS portion of the MRS extruder below about 5 millibars; (E) passing the resulting polymer melt through at least one filter having a micron rating of less than about 50 microns; and (F) forming the recycled polymer into bulked continuous carpet filament that consists essentially of recycled PET.

In particular embodiments, a process for producing bulked continuous carpet filament from recycled polymer utilizes two vacuum pumps in combination with a single extruder. In various embodiments, the dual vacuum arrangement (e.g., at least two vacuum pumps) operably coupled to the single extruder (e.g., MRS extruder) may be configured remove one or more impurities from recycled polymer as the recycled polymer passes through the extruder such that the process: (1) is more effective than earlier processes in removing contaminates and water from the recycled polymer; (2) allows for an increased throughput through a single extruder, which may result in a doubling of a number of thread lines produced from a single extruder; (3) results in a desired intrinsic viscosity for the extruded recycled polymer at the increased throughput; and/or (4) reduces an amount of downtime of a particular production line as a result of cleaning the two vacuum pumps.

A method of manufacturing a fiber-reinforced composite material which is molded by impregnating a fiber-reinforced sheet with a resin and curing the resin includes: placing the fiber-reinforced sheet in a cavity of a mold; and molding the fiber-reinforced composite material, the molding including injecting the resin into the cavity of the mold, impregnating the fiber-reinforced sheet with the resin, and curing the resin. In the molding, after fine air bubbles contained in the resin are placed at a predetermined position of the cavity, the resin is cured.