A microneedle structure, a manufacturing method therefor, and a manufacturing apparatus therefor are presented. The microneedle structure manufacturing method according to one embodiment of the present invention comprises the steps of: a) injecting, into a lower mold comprising a microneedle intaglio, a polymer solution containing a biocompatible polymer; and b) coupling a shape control mold, which comprises a protrusion, to the lower mold such that one end of the protrusion of the shape control mold is impregnated with the biocompatible polymer solution injected into the microneedle intaglio.

A novel cutting-edge structure and method and apparatus for manufacturing the cutting-edge structure is provided. The cutting-edge structure is comprised of naturally derived or renewable material at greater than 50% by volume fraction. In one embodiment, the naturally derived material is a cellulose nanostructure such as a cellulose nanocrystal. The cellulose nanocrystal is processed using a base or mold structure to provide a cutting edge of any shape such as linear or circular edge structures. The process includes dual cure steps to produce an optimal cutting-edge structure without shrinkage. The formed cutting-edge structure can be utilized as a razor blade as it is formed with very sharp tip and edge suitable for cutting hair. The base structure can form one or more cutting-edge structures simultaneously.

A mold for building coating products obtained from composite liquid mixtures is described. The mold includes a base plate, having a plurality of through holes; and a die, configured for incorporating the base plate therein. On the upper surface of the die there are a plurality of shapes of the front surface in negative of each coating product to be manufactured and a molding grid open at the upper part, configured to be pressure applied above the die. The molding grid has side walls which define the perimeter edges of each coating product. Between the molding grid side walls separate bowls are formed for containing a single coating product. Each side wall is inclined at an acute angle with respect to a vertical plane, to confer to each side wall a sharp-pointed and tapered shape from top towards bottom with respect to the entire mold for facilitating the extraction of the finished coating products.

The present invention relates to an apparatus for dispensing and curing of liquid media, comprising a supply system comprising at least one reservoir for the liquid medium, a nozzle for ejecting the liquid medium into a mould (10) and/or onto a workpiece and means (22) connecting the nozzle and the reservoir; and a microwave system (16,18) which comprises a microwave source (16) for producing microwave radiation for irradiating the liquid medium in an irradiation zone (20) in the supply system, wherein the irradiation zone (20) is arranged between the reservoir and the nozzle. The apparatus further comprises a displacement assembly for translating and/or rotating the nozzle with respect to the mould (10) and/or the workpiece in a controlled manner. According to further aspects, the invention also relates to a system and a method for dispensing and curing of liquid media.

A mold for casting a micro-scale dry adhesive structure includes an upper surface including a first cavity having a first depth, a negative pattern for an array of micro-scale structures defined in a surface of the first cavity, and at least one second cavity having a second depth defined in the cavity outside of the negative pattern for the array of micro-scale structures, the at least one second cavity defining a negative pattern for a standoff of the micro-scale dry adhesive structure.

Provided are a transdermal absorption sheet capable of achieving control of the dissolution rate and suppression of diffusion of a drug, and a method of producing the same. A transdermal absorption sheet includes a sheet portion, and a plurality of needle-like protruding portions formed by a plurality of frustum portions arranged on the sheet portion and needle portions arranged on the frustum portions, in which at least one of the needle-like protruding portions has a cavity portion extending from the sheet portion to the frustum portion.

A method of manufacturing marine riser buoyancy elements includes providing a master mold and mold inserts such that a range of buoyancy elements may be manufactured from one master mold and providing the mold inserts such that an annular space between the riser main conduit and the buoyancy elements, or a groove width between the buoyancy elements may be varied during manufacture.

An internal release agent includes at least one phosphodiester represented by the following general formula (1).

##STR00001##

In the formula, R.sub.1 and R.sub.2 independently represent a hydrocarbon group having 1 to 30 carbon atoms, which is optionally substituted with at least one hydroxyl group, and R.sub.3 represents an alkylene group having 2 to 4 carbon atoms. A plurality of R.sub.3's may be the same as or different from each other. M represents a hydrogen atom, an ammonium ion, an alkali metal ion, or a monovalent/divalent alkali earth metal ion, and n is an integer of 1 to 60.

An internal release agent includes at least one phosphodiester represented by the following general formula (1).

##STR00001##

In the formula, R.sub.1 and R.sub.2 independently represent a hydrocarbon group having 1 to 30 carbon atoms, which is optionally substituted with at least one hydroxyl group, and R.sub.3 represents an alkylene group having 2 to 4 carbon atoms. A plurality of R.sub.3's may be the same as or different from each other. M represents a hydrogen atom, an ammonium ion, an alkali metal ion, or a monovalent/divalent alkali earth metal ion, and n is an integer of 1 to 60.

The present disclosure provides processes for producing polyethylene resins. In at least one embodiment, a polyethylene has: a density of from about 0.91 g/cm.sup.3 to about 0.94 g/cm.sup.3; a value of Mz of about 1,500,000 g/mol or greater; and a ratio of Mz to Mw of about 7 or greater. A process includes introducing a first feed stream having ethylene monomer and a first free radical initiator to a first inlet of a first reaction zone, where the first reaction zone has a first inlet temperature. The process further includes introducing a second feed stream having ethylene monomer and a second free radical initiator to a second inlet of a second reaction zone, where the second reaction zone has a second inlet temperature that is the same or different than the first inlet temperature.