According to the invention an apparatus for extrusion of a structured extrudate, which can be introduced into a human or animal body, is provided. This apparatus comprises an extrusion apparatus with a housing, whereas the housing has a revolving lateral wall which at a front end in the direction of production is provided with a nozzle wall with an outlet nozzle, and in the direction of production prior to that with a global sleeve, whereas the space in the housing between the global sleeve, the lateral wall and the outlet nozzle confines an extrusion space, and the housing in the region of the extrusion space can be connected to a polymer feeding appliance. In the global sleeve at least one guide channel extending in the direction of production is provided in order to be able to insert at least one rod-shaped body from a feeding appliance for rod-shaped bodies into the extrusion space, whereas the at least one guide channel is arranged in about straight alignment to the outlet nozzle.

A housing cleaning device for cleaning a housing of a screw machine comprises a support unit displaceable relative to the housing, and at least one housing cleaning unit arranged at the support unit, for cleaning an inner wall of the housing, wherein the at least one housing cleaning unit can be reversibly inserted into the housing. An associated shaft cleaning device for cleaning at least one treatment element shaft of the screw machine comprises a cleaning chamber, in which the at least one treatment element shaft can be arranged, and at least one shaft cleaning unit arranged in the cleaning chamber.

The disclosure features polymorphs of a prodrug dimer of dexamethasone linked at the 21-C and 21′-C carbons via a carbonate-triethylene glycol-carbonate linker. Also disclosed are pharmaceutical compositions and articles comprising said polymorphs, and the use thereof in the treatment of a disease or condition, e.g. via the extended or controlled release of dexamethasone from said articles.

The present disclosure relates generally to an extruder for producing an extrudate. The present disclosure relates more particularly to an extruder including an extruder body having at least one material inlet and an exit opening. A rotatable outlet is coupled to the exit opening of the extruder body and is configured to rotate as the extrudate is expelled from the extruder body.

The present disclosure relates generally to an extruder for producing an extrudate. The present disclosure relates more particularly to an extruder including an extruder body having at least one material inlet and an exit opening. A rotatable outlet is coupled to the exit opening of the extruder body and is configured to rotate as the extrudate is expelled from the extruder body.

The present disclosure relates generally to an extruder for producing an extrudate. The present disclosure relates more particularly to an extruder including an extruder body having at least one material inlet and an exit opening. A rotatable outlet is coupled to the exit opening of the extruder body and is configured to rotate as the extrudate is expelled from the extruder body.

The present disclosure relates generally to an extruder for producing an extrudate. The present disclosure relates more particularly to an extruder including an extruder body having at least one material inlet and an exit opening. A rotatable outlet is coupled to the exit opening of the extruder body and is configured to rotate as the extrudate is expelled from the extruder body.

A seal for a vacuum lifter and method of manufacture wherein the seal has a continuous unbroken outer fluid resistant skin of elastomer which forms a boundary around a homogeneous cellular structure with no interior seams or joints.

A system (10) for butt-joining two or more rubber strips (B1, B2) selected in accordance with a predetermined rubber mixture recipe in order to feed at least one extruder with a complex strip of rubber material (B12) made from the butt joined rubber strips is disclosed. The system includes at least one conveyor that transports the rubber strips from an inlet (12) of the system to an outlet (14) of the butt-joining system; a frame (18) that operationally supports the conveyor to allow the continuous transport of the rubber strips and also to allow the simultaneous butt-joining of the rubber strips fed to the system; and a roller system (20) that butt-joins the rubber strips without penetration. The invention also relates to a process for butt-joining rubber strips that is performed by the system.

A mixing method provided by the invention comprises steps of melting a solid-state polymer raw material into a flowable molten raw material fluid to flow into a mixing space at a first volume flow rate, when the raw material fluid entering the mixing space, introducing a foaming agent in a fluid form into the mixing space simultaneously or at a different time, mixing the foaming agent with the molten raw material fluid into a mixture in the mixing space, circulating the mixture in the mixing space at a second volume flow rate, and causing the second volume flow rate greater than the first volume flow rate.