The invention relates to a process for bonding a silicone or silicone based material to a polyurethane and use of the bonded silicone-polyurethane in the manufacture of biomaterials, devices, articles or implants, in particular long term implantable medical devices in the fields of cardiology, orthopaedics, plastic surgery and gastroenterology. The process involves the steps of (a) flame treating a surface of the silicone or silicone based material and (b) bonding the polyurethane to the flame treated surface of the silicone or silicone based material.

A method for producing a helical casting pattern. The method including: providing a pattern body having a longitudinal axis, a cavity extending in the direction of the longitudinal axis, and a pattern body wall that surrounds the cavity; providing a processing tool for creating a recess; arranging the pattern body and the processing tool such that the processing tool extends at least partially through the pattern body wall in the radial direction with respect to the longitudinal axis; and rotatably driving at least one of the processing tool and the pattern body about one of the longitudinal axis of the pattern body and an axis parallel thereto, relative to one another, with a relative movement between the pattern body and the processing tool in a direction parallel to the longitudinal axis being produced one of continuously or at least intermittently during or in alternation with the relative rotational movement.

A method for producing a helical casting pattern. The method including: providing a pattern body having a longitudinal axis, a cavity extending in the direction of the longitudinal axis, and a pattern body wall that surrounds the cavity; providing a processing tool for creating a recess; arranging the pattern body and the processing tool such that the processing tool extends at least partially through the pattern body wall in the radial direction with respect to the longitudinal axis; and rotatably driving at least one of the processing tool and the pattern body about one of the longitudinal axis of the pattern body and an axis parallel thereto, relative to one another, with a relative movement between the pattern body and the processing tool in a direction parallel to the longitudinal axis being produced one of continuously or at least intermittently during or in alternation with the relative rotational movement.

A method is provided for surface smoothing an additively manufactured shaped part consisting of plastic. The method has an explosion step with which the surface of the shaped part is smoothed in a process chamber by igniting a combustible process gas introduced into the process chamber, the surface of the shaped part being partly dissolved in at least some sections by the ignited process gas. Also provided is a device for surface smoothing additively manufactured shaped parts consisting of plastic.

A method is provided for surface smoothing an additively manufactured shaped part consisting of plastic. The method has an explosion step with which the surface of the shaped part is smoothed in a process chamber by igniting a combustible process gas introduced into the process chamber, the surface of the shaped part being partly dissolved in at least some sections by the ignited process gas. Also provided is a device for surface smoothing additively manufactured shaped parts consisting of plastic.

A scaffold strut is shaped to improve hemocompatibility. After laser cutting, the scaffold is placed on a work piece and its struts are shaped by flame polishing or brushing. The abluminal surfaces and luminal surfaces can have corners rounded. The strut can have a sloped surface on its luminal side without reducing strut thickness needed for strength.

The disclosure provides microstructured articles and methods useful for detecting an analyte in a sample. The articles include microwell arrays. The articles can be used with an optical system component in methods to detect or characterize an analyte.

The disclosure provides microstructured articles and methods useful for detecting an analyte in a sample. The articles include microwell arrays. The articles can be used with an optical system component in methods to detect or characterize an analyte.

The invention relates to a process for bonding a silicone or silicone based material to a polyurethane and use of the bonded silicone-polyurethane in the manufacture of biomaterials, devices, articles or implants, in particular long term implantable medical devices in the fields of cardiology, orthopaedics, plastic surgery and gastroenterology. The process involves the steps of (a) flame treating a surface of the silicone or silicone based material and (b) bonding the polyurethane to the flame treated surface of the silicone or silicone based material.

The invention relates to a process for bonding a silicone or silicone based material to a polyurethane and use of the bonded silicone-polyurethane in the manufacture of biomaterials, devices, articles or implants, in particular long term implantable medical devices in the fields of cardiology, orthopaedics, plastic surgery and gastroenterology. The process involves the steps of (a) flame treating a surface of the silicone or silicone based material and (b) bonding the polyurethane to the flame treated surface of the silicone or silicone based material.