The present invention relates to an animal model with ischemic heart disease, by a 3-dimensional bioprinted occluder and method for producing the same.

A method for additive production of a component, which includes the additive construction of the component on a component platform having an opening, wherein, during the first part of the additive construction of the component an auxiliary structure is produced additively around the opening of the component platform. The method further includes the introduction of a device through the opening into a cavity defined by the auxiliary structure, wherein, during a second part of the additive construction, following the first part of the additive construction, properties of the component to be produced are influenced and/or measured by the device. A component is produced by the method and an apparatus for the additive production of the component, includes the component platform having the opening and the closure.

A method for additive production of a component, which includes the additive construction of the component on a component platform having an opening, wherein, during the first part of the additive construction of the component an auxiliary structure is produced additively around the opening of the component platform. The method further includes the introduction of a device through the opening into a cavity defined by the auxiliary structure, wherein, during a second part of the additive construction, following the first part of the additive construction, properties of the component to be produced are influenced and/or measured by the device. A component is produced by the method and an apparatus for the additive production of the component, includes the component platform having the opening and the closure.

The disclosure relates to additively manufactured (AM) composite structures such as panels for use in transport structures or other mechanized assemblies. An AM core may be optimized for an intended application of a panel. In various embodiments, one or more values such as strength, stiffness, density, energy absorption, ductility, etc. may be optimized in a single AM core to vary across the AM core in one or more directions for supporting expected load conditions. In an embodiment, the expected load conditions may include forces applied to the AM core or corresponding panel from different directions in up to three dimensions. Where the structure is a panel, face sheets may be affixed to respective sides of the core. The AM core may be a custom honeycomb structure. In other embodiments, the face sheets may have custom 3-D profiles formed traditionally or through additive manufacturing to enable structural panels with complex profiles. The AM core may include a protrusion to provide fixturing features to enable external connections. In other embodiments, inserts, fasteners, or internal channels may be co-printed with the core. In still other embodiments, the AM core may be used in a composite structure such as, for example a rotor blade or a vehicle component.

The disclosure relates to additively manufactured (AM) composite structures such as panels for use in transport structures or other mechanized assemblies. An AM core may be optimized for an intended application of a panel. In various embodiments, one or more values such as strength, stiffness, density, energy absorption, ductility, etc. may be optimized in a single AM core to vary across the AM core in one or more directions for supporting expected load conditions. In an embodiment, the expected load conditions may include forces applied to the AM core or corresponding panel from different directions in up to three dimensions. Where the structure is a panel, face sheets may be affixed to respective sides of the core. The AM core may be a custom honeycomb structure. In other embodiments, the face sheets may have custom 3-D profiles formed traditionally or through additive manufacturing to enable structural panels with complex profiles. The AM core may include a protrusion to provide fixturing features to enable external connections. In other embodiments, inserts, fasteners, or internal channels may be co-printed with the core. In still other embodiments, the AM core may be used in a composite structure such as, for example a rotor blade or a vehicle component.

An apparatus includes a precursor dispenser for dispensing a precursor material into a workspace, one or more acoustic sources configured to direct acoustic waves towards the workspace to provide acoustic fields that arrange the precursor material in a three-dimensional shape in the workspace, one or more sensors configured to detect a distribution of the precursor material in the workspace, and an electronic controller in communication with the precursor dispenser, the one or more acoustic sources, and the one or more sensors, the electronic controller being programmed to cause the one or more acoustic sources to adjust the acoustic fields to reduce deviations in the distribution of the precursor material from the three-dimensional shape in the workspace.

An apparatus includes a precursor dispenser for dispensing a precursor material into a workspace, one or more acoustic sources configured to direct acoustic waves towards the workspace to provide acoustic fields that arrange the precursor material in a three-dimensional shape in the workspace, one or more sensors configured to detect a distribution of the precursor material in the workspace, and an electronic controller in communication with the precursor dispenser, the one or more acoustic sources, and the one or more sensors, the electronic controller being programmed to cause the one or more acoustic sources to adjust the acoustic fields to reduce deviations in the distribution of the precursor material from the three-dimensional shape in the workspace.

The disclosure relates to additively manufactured (AM) composite structures such as panels for use in transport structures or other mechanized assemblies. An AM core may be optimized for an intended application of a panel. In various embodiments, one or more values such as strength, stiffness, density, energy absorption, ductility, etc. may be optimized in a single AM core to vary across the AM core in one or more directions for supporting expected load conditions. In an embodiment, the expected load conditions may include forces applied to the AM core or corresponding panel from different directions in up to three dimensions. Where the structure is a panel, face sheets may be affixed to respective sides of the core. The AM core may be a custom honeycomb structure. In other embodiments, the face sheets may have custom 3-D profiles formed traditionally or through additive manufacturing to enable structural panels with complex profiles. The AM core may include a protrusion to provide fixturing features to enable external connections. In other embodiments, inserts, fasteners, or internal channels may be co-printed with the core. In still other embodiments, the AM core may be used in a composite structure such as, for example a rotor blade or a vehicle component.

The present invention provides methods, processes, and systems for the manufacture of three-dimensional articles made of polymers using 3D printing. A layer of prepolymer is deposited on a build plate to form a powder bed. The deposited powder bed is heated to about 50° C. to about 170° C. Then, a solution of activating agent is printed on the powder bed in a predetermined pattern, and a stimulus is applied converting the prepolymer to the final polymer. After a predetermined period of time, sequential layers are printed to provide the three-dimensional article. The three-dimensional object can be cured to produce the three-dimensional article composed of the final polymers.

Methods that prevent oxygen inhibition of a light-initiated polymerization reaction by purging the oxygen from reaction surfaces using inert gas flow. In some embodiments, oxygen is purged using a gas diffusion system that introduces, via a diffuser, an inert gas into a workspace between a UV light source and a UV curable layer of a workpiece. The diffuser may be made of a transparent or diffuse material to allow UV light to pass through it, and includes an array of micro-holes for the gas to pass through towards the workpiece. The inert gas flow may be heated to maintain a desired and uniform reaction temperature.