The invention relates to a device and a method for the thermal reshaping of hose blanks from preferably pre-extruded elastic raw hose material, wherein during the reshaping the hose blank is arranged in a shell-like, single- or multi-piece molding tool with a hollow body, wherein the inner side of the hollow body corresponds as a negative to the shape to be impressed onto the hose blank, wherein the tempering of the molding tool that is necessary for reshaping occurs by means of clamp-like tempering elements which are shaped congruently to the outer surface of the mold and which close form-fittingly over the mold, while the molding tool itself does not comprise any tempering system at all, in particular no ducts or other hollow spaces for circulating a tempering medium, and wherein the temperature of each tempering element is kept constant during the process, while, to modify the temperature of the molding tool, a different tempering element with a correspondingly constant temperature is positioned against the molding tool; in the claimed device, the molding tool is free of internal ducts and other hollow spaces for the circulation of a tempering medium, while half or partial shells, which are separate from the mold and which close form-fittingly over the mold, are provided to temper the molding tool, wherein the inner sides of said shells which face the molding tool are congruent with the outer side of said molding tool and wherein the shells comprise an arrangement for keeping the temperature of each tempering element constant during the process, in particular internal hollow spaces for the perfusion of a tempering medium, and wherein at least one mechanism is provided for selectively closing different tempering elements at different temperatures around the molding tool.

A bioresorbable, implantable device having controlled drug delivery is disclosed herein. The bioresorbable, implantable device is configured as a film, a roll, a tube, and a stent. The bioresorbable, implantable device is configured to release an active ingredient (the drug) from the bioresorbable, implantable device when the bioresorbable, implantable device is implanted within a body. The bioresorbable, implantable device is configured to control the onset of the release of the drug, the sequence of drug delivery, and the duration of drug delivery by embedding the drug within at least one therapeutic layer positioned within bioresorbable, implantable device.

A system for removing kinks in a catheter and/or reforming a catheter of a medical device is provided. The system can include at least one clamp, a heat device, and a pair of rolling wheels. In at least one example, the at least one clamp can be operable to secure the catheter. In some examples, the heat device can be operable to provide heat to the catheter. In some examples, the pair of rolling wheels can be operable to receive the catheter of the medical device therebetween such that when the catheter is moved along a longitudinal axis between the pair of rolling wheels, the pair of rolling wheels reforms the catheter.

A multilayer bioresorbable stent having sustained drug delivery is disclosed herein. The bioresorbable stent releases a therapeutic substance from the body of the bioresorbable stent starting when the bioresorbable stent is implanted within an anatomical lumen and ending when the entire mass of the bioresorbable stent is no longer present within the anatomical lumen. The bioresorbable stent releases the therapeutic substance gradually during the treatment as the mass of the each layer of the bioresorbable stent erodes. Methods of making the therapeutic layers within the bioresorbable sent are further disclosed. Sustained drug delivery reduces the risk of late and very late stent thrombosis.

The present disclosure provides a staged shearing and forming method for a T-bar cylindrical member, comprising: controlling a shear working surface of a shear spinning wheel in contact with a surface of a cylindrical member blank; controlling a circumferential rotation of the cylindrical member blank; controlling a working surface of a flow spinning wheel to be in perpendicular contact with a surface of the unsaturated I-bar cylindrical member and controlling the cylindrical member blank to be maintained in a circumferential rotational state; controlling the flow spinning wheel to thin one side of the unsaturated I-bar cylindrical member; controlling a fractal working surface of a fractal spinning wheel in contact with a top of the saturated I-bar structure; controlling a working surface of a flat spinning wheel to be in perpendicular contact with a surface of the Y-bar cylindrical member.

A system for removing kinks in a catheter and/or reforming a catheter of a medical device is provided. The system can include at least one clamp, a heat device, and a pair of rolling wheels. In at least one example, the at least one clamp can be operable to secure the catheter. In some examples, the heat device can be operable to provide heat to the catheter. In some examples, the pair of rolling wheels can be operable to receive the catheter of the medical device therebetween such that when the catheter is moved along a longitudinal axis between the pair of rolling wheels, the pair of rolling wheels reforms the catheter.