The present invention relates to pharmaceutical dosage forms, for example to a tamper resistant dosage form including an opioid analgesic, and processes of manufacture, uses, and methods of treatment thereof.

The present invention relates to pharmaceutical dosage forms, for example to a tamper resistant dosage form including an opioid analgesic, and processes of manufacture, uses, and methods of treatment thereof.

The present invention relates to pharmaceutical dosage forms, for example to a tamper resistant dosage form including an opioid analgesic, and processes of manufacture, uses, and methods of treatment thereof.

The invention provides a method for manufacturing a 3D item (1) by means of 3D printing. The method comprises the step of depositing, during a printing stage, 3D printable material (201) to provide 3D printed material (202), wherein the 3D printable material (201) comprises a core-shell filament (320) comprising (i) a core (321) comprising a core material (1321) having one or more of a core glass temperature Tg1 and a core melting temperature Tm1 and (ii) a shell (322) comprising a shell material (1322) having one or more of a shell glass temperature Tg2 and a shell melting temperature Tm2, wherein one or more of the shell glass temperature Tg2 and the shell melting temperature Tm2 is lower than one or more of the core glass temperature Tg1 and the core melting temperature Tm1. The method further comprises the step of heating, during a finishing stage, the 3D printed material (202) to a temperature equal to or higher than one or more of the shell glass temperature Tg2 and the shell melting temperature Tm2, and equal to or lower than one or more of the core glass temperature Tg1 and the core melting temperature Tm1.

An apparatus, method, or platter for modifying mesa sidewalls of a template by cleaning or coating the mesa sidewalls. In which the template has a pattern area on a first surface of a mesa. Mesa sidewalls surround the first surface of the mesa. The mesa sidewalls are exposed to a gas. The gas modifies the mesa sidewalls. Resistance to the flow of gas towards the pattern area is provided.

In an example implementation, a method of cleaning parts includes placing the parts into a variable compression chamber, filling the chamber with a liquid, and forcing pressurized gas to dissolve into the liquid to form a gas-liquid solution. The method includes cycling the pressure within the chamber around a gas solubility pressure level to repeatedly bring gas molecules out of the solution as gas bubbles, and force the gas molecules to dissolve back into the solution.

The invention relates to a process and an apparatus for chemical smoothing of a plastic part (10) produced by selective layerwise consolidation of a construction material. The process comprises the steps of: temperature-controlling the plastic part to a first temperature; temperature-controlling solvent vapour (8) comprising a solvent to a second temperature; subjecting the plastic part (10) to the solvent vapour (8) temperature-controlled to the second temperature for a particular duration, wherein the subjecting of the plastic part (10) to the solvent vapour (8) has the result that an outer layer of the plastic part (10) is liquefied; and discharging at least a portion of the solvent vapour (8) after the particular duration, wherein the plastic part (10) is stationary from commencement of the temperature-controlling of the plastic part until termination of the discharging of the solvent vapour (8).

The present invention relates to pharmaceutical dosage forms, for example to a tamper resistant dosage form including an opioid analgesic, and processes of manufacture, uses, and methods of treatment thereof.

The present invention relates to pharmaceutical dosage forms, for example to a tamper resistant dosage form including an opioid analgesic, and processes of manufacture, uses, and methods of treatment thereof.

The present invention relates to pharmaceutical dosage forms, for example to a tamper resistant dosage form including an opioid analgesic, and processes of manufacture, uses, and methods of treatment thereof.