An artificial eye lens (1) having an optical part (2) which has a first optical side (4) and an opposite, second optical side (5). The optical part (2) has a diffractive grating structure that contributes to an optical imaging property of the optical part (2). The diffractive grating structure is an amplitude grating (6) formed in the optical part (2) as a laser structure. A method for producing an artificial eye lens (1) where the amplitude grating (6) is produced with a laser apparatus (17), and a pulsed laser beam (22) having a pulse length of between 100 fs and 20 ps, a wavelength of between 320 nm and 1100 nm, a pulse repetition rate of between 1 kHz and 10 MHz, a focus diameter of less than 5 m, and a power density of greater than 10.sup.6 W/cm.sup.2.

Intraocular implants and methods of making intraocular implants are provided. The intraocular implant can include a mask adapted to increase depth of focus. The method of manufacturing the implant can include positioning the mask with an aperture on a protruding pin of a positioning mold portion. The protruding pin can be configured to center the mask in the intraocular lens.

An electronic device can comprise a first electronic module; a second electronic module; and a hermetic electric interconnect to hermetically couple them. The hermetic electric interconnect can comprise a bottom metal layer; a bottom insulating layer, deposited on the bottom metal layer to insulate the bottom metal layer; an interconnect metal layer, deposited on the bottom insulating layer, and deposited to form a bottom sealing ring; and patterned to form electrical connections between contact pads, and to form a middle sealing ring; a patterned top insulating layer, deposited on the interconnect metal layer to insulate the interconnect metal layer; and patterned to form feedthrough holes; and a top metal layer, deposited on the top insulating layer to start forming contacts by filling the feedthrough holes; and patterned to complete forming contacts through the feedthrough holes, to form a separate barrier layer, and to complete forming the top sealing ring.

A system/method allowing personalized ex vivo customization of a generic ophthalmic lens blank (OLB) or ophthalmic lens with known diopter (OKD) based on localized field-measured patient characteristics is disclosed. The OLB is composed of a clear material that contains an ultraviolet (UV) absorbing compound. The refractive index of a portion of the clear material may be customized by spatial modification (CSM) of its refractive index via the use of pulsed laser radiation (PLR). The customization of clear material (i) creates a lens which cannot be created otherwise, or (ii) eliminates the need for remote laboratory fabrication of a customized intraocular lens (IOL) for the patient. The OLB is retained within a secured lens container (SLC) providing for precise physical orientation of the OLB haptics and OLB lens structure with respect to the application of PLR to the OLB. The SLC contains a lens filler material (LFM) covering the OLB and is hermetically sealed after the OLB has been positioned within the SLC interior and prior to sterilization of the SLC+OLB combination.

An intraocular lens and a method of constructing the intraocular lens are described. The intraocular lens is implanted in a human eye to treat conditions of the eye. The intraocular lens includes a central deformable optic and an annular ring coupled to the deformable optic. The intraocular lens is made by subjecting the deformable optic to compressive forces that reduce the optical power of the deformable optic, and then molding the annular lens to the deformable optic while the deformable optic is undergoing the compressive forces. Once the compressive forces are released, the deformable optic stresses the annular ring along a radial axis of the deformable optic when the intraocular lens is in a natural, unstressed state. The stress or tension between the deformable optic and the annular ring keep the deformable optic from developing deformities that cause visual aberrations.

Intraocular implants and methods of making intraocular implants are provided. The intraocular implants can improve the vision of a patient, such as by increasing the depth of focus of an eye of a patient. In particular, the intraocular implants can include a mask having an annular portion with a relatively low visible light transmission surrounding a relatively high transmission central portion such as a clear lens or aperture. This construct is adapted to provide an annular mask with a small aperture for light to pass through to the retina to increase depth of focus. The intraocular implant may have an optical power for refractive correction. The intraocular implant may be implanted in any location along the optical pathway in the eye, e.g., as an implant in the anterior or posterior chamber.

The present disclosure generally relates to local therapies for the eye and, more particularly, to shaped controlled-release ocular implant devices, including methods for making and using such devices, for delivery of therapeutic agents to the eye. A molded two-layer ocular implant comprises a therapeutic agent for treatment or prevention of a disorder of the eye. The implant comprises a polymer layer and a silicone adhesive layer with a therapeutic agent interspersed therein and joined to the polymer layer. This implant is for placement in the sub-Tenon's space of the eye and provides sustained release of the therapeutic agent during the treatment or prevention of the disorder of the eye.

A continuous additive fabrication system comprises a bath of photopolymer resin and a light source assembly having a light source and a motorized variable aperture. The light source assembly is operable to generate a focus point in the bath of photopolymer resin, the shape of the focus point at a curing plane within the bath of photopolymer resin corresponding to the shape of the motorized variable aperture. The continuous additive fabrication system further comprises a platform configured to support a build object and a drive mechanism (coupled to at least one of the platform and the light source assembly) configured to continuously move the curing plane through the bath of photopolymer resin. A size and/or shape of the motorized variable aperture is changed while the curing plane in continuously moved through the bath of photopolymer resin.

A method of altering a refractive property of a crosslinked acrylic polymer material by irradiating the material with a high energy pulsed laser beam to change its refractive index. The method is used to alter the refractive property, and hence the optical power, of an implantable intraocular lens after implantation in the patient's eye. In some examples, the wavelength of the laser beam is in the far red and near IR range and the light is absorbed by the crosslinked acrylic polymer via two-photon absorption at high laser pulse energy. The method also includes designing laser beam scan patterns that compensate for effects of multiphone absorption such as a shift in the depth of the laser pulse absorption location, and compensate for effects caused by high laser pulse energy such as thermal lensing. The method can be used to form a Fresnel lens in the optical zone.

An intraocular lens (IOL) for implantation within a capsular bag of a patient's eye comprises an optical structure and a haptic structure. The optical structure comprises a planar member, a plano convex member, and a fluid optical element defined between the planar member and the plano convex member. The fluid optical element has an optical power. The haptic structure couples the planar member and the plano convex member together at a peripheral portion of the optical structure. The haptic structure comprises a fluid reservoir in fluid communication with the fluid optical element and a peripheral structure for interfacing to the lens capsule. Shape changes of the lens capsule cause one or more of volume or shape changes to the fluid optical element in correspondence to deformations in the planar member to modify the optical power of the fluid optical element.