Triboelectric nanogenerators that operate in a vertical contact separation mode and methods for fabricating the triboelectric generators are provided. Also provided are methods for using the triboelectric nanogenerators to harvest mechanical energy and convert it into electric energy. In the TENGs, one or both of the triboelectrically active layers comprises a cellulose that has been chemically treated to alter its electron affinity.

Microneedle arrays and methods of forming the same can include one or more bioactive components bonded to a biocompatible material such that the one or more bioactive components are cleavable in vivo to release the bioactive component from the biocompatible material.

A synthetic reed for use with a woodwind instrument includes a synthetic resin matrix with randomly distributed suspended cane particles. Synthetic fibers, which may comprise one or more different material filaments, may also be impregnated within resin matrix. The cane particles can be present in a concentration of approximately 0.5-10% by volume and at least a majority of the cane particles in the resin matrix can be less than 100 micrometers. The matrix may be formed from two components including an epoxy resin component and a hardener component. The reed exhibits improved strength properties usually provided by synthetics with the warmer sonic properties associated with natural cane reeds and preferred by musicians.

A laminate film manufacturing method is capable of preventing thickness unevenness of a cured layer and preventing wrinkling of the entire laminate film. A laminate film is manufactured by applying a coating solution including an active radiation curable resin to a surface of a first film that is continuously transported in an application part to form a coated film in a lamination part, laminating a second film that is continuously transported on the coated film to sandwich the coated film between the first film and the second film, and in a state in which the coated film is sandwiched between the first film and the second film, winding the first film around a backup roller and irradiating the coated film with infrared rays from an ultraviolet irradiation device while continuously transporting the first film to cure the coated film in a curing part so as to form a cured layer.

A laminate film manufacturing method is capable of preventing thickness unevenness of a cured layer and preventing wrinkling of the entire laminate film. A laminate film is manufactured by applying a coating solution including an active radiation curable resin to a surface of a first film that is continuously transported in an application part to form a coated film in a lamination part, laminating a second film that is continuously transported on the coated film to sandwich the coated film between the first film and the second film, and in a state in which the coated film is sandwiched between the first film and the second film, winding the first film around a backup roller and irradiating the coated film with infrared rays from an ultraviolet irradiation device while continuously transporting the first film to cure the coated film in a curing part so as to form a cured layer.

The invention provides implantable drug delivery devices comprising a core comprising a polymer (or polymer blend) and one or more drugs or pharmaceutical substances, and an outer shell comprising a polymer (or polymer blend) and one or more porogen materials. The invention reduces burst release of drug. Pharmaceuticals such as triiodothyronine (T3) or ropinirole can be delivered by the devices.

A bone fixation device made of polysaccharide particles or microspheres fused into a solid structure is provided herein. The bone fixation device may be in the form of an orthopedic screw, orthopedic pin, or orthopedic plate. Methods of making the bone fixation devices described herein are provided as are methods of treating patients in need of bone repair or replacement by implanting a bone fixation device described herein in the patient at a site of bone damage, ligament damage, or bone deformity.

A two dimensional unitary preform sheet including a substrate and a fiber bundle arranged on the substrate and attached to the substrate by a plurality of stitches of a thread, which may be a thermoplastic thread. The two dimensional unitary preform sheet is configurable into a three dimensional preform. According to embodiments, the fiber bundle includes carbon fibers, glass fibers, aramid fibers, or a combination thereof. According to embodiments, the two dimensional unitary preform sheet is cut in a pattern that is foldable into the three dimensional preform. A method for making a three dimensional preform is also provided, which includes forming a two dimensional unitary preform sheet and placing the two dimensional unitary preform in a press to bend the two dimensional unitary preform into the shape of the three dimensional preform.

Biodegradable thermoformed articles are disclosed. The thermoformed articles are formed from a biodegradable polymer composition. The polymer composition contains a cellulose ester polymer, a plasticizer, and one or more other additives. Thermoformed articles can be made in accordance with the present disclosure having low haze and high clarity.

A manufacturing method for a micro-needle device includes following steps: a target tissue basic information obtaining step, a micro-needle template obtaining step, a micro-needle material adding step, a micro-needle semi-product obtaining step, and a micro-needle device obtaining step. The inner tissue distribution information is obtained by the application of optical coherence tomography. The micro-needle template is obtained according to the skin surface curvature information and the inner tissue distribution information. The micro-needle template has a plurality of areas and a plurality of mold holes. One or both of the diameter and the depth of the mold hole is determined by the inner tissue distribution information, and the curvature radius of the areas is determined by the skin surface curvature information. The manufacturing method for a micro-needle device is applicable to micro-needles with mixed configurations as well as micro-needles with syringe configurations.