The present disclosure is drawn to material sets and 3-dimensional printing systems that include a fusing agent. One example of a material set can include a fusing agent and a detailing agent. The fusing agent can include water, a carbon black pigment, and a water-soluble co-solvent in an amount from 20 wt % to 60 wt %. The detailing agent can include water and a black dye. In another example, a material set can include a fusing agent and a thermoplastic polymer powder.

An eyeglass lens material can be used to make an eyeglass lens and at least includes a mixture of Ag/SiO.sub.x composite nanoparticles and at least one type of monomer. The eyeglass lens is capable of blocking blue light. The monomer undergoes a material curing procedure to form a main body that contains and is mixed with the Ag/SiO.sub.x composite nanoparticles. As the Ag/SiO.sub.x composite nanoparticles in the eyeglass lens material can absorb relatively high-energy blue light, a contact lens made of the eyeglass lens material can block blue light.

A water soluble polymer composition comprising a water soluble polymer (e.g., polyvinyl alcohol-co-vinylpyrrolidinone (PVOH-co-PVP)) and a sugar (e.g., trehalose).

Described are microneedle devices comprising an electron beam crosslinked or photocrosslinked polymer material, and methods of making and using them, such as for drug delivery or sampling biological fluids.

A method for automatic printing of a three dimensional heterogeneous structure in accordance with a computer-aided design procedure, including the steps of: aspirating a first portion consisting of a first material (M1) in liquid form, from a first liquid container into a capillary (C); aspirating a second portion consisting of a second material (M2) in liquid form different than the first material (M1), from a second liquid container into said capillary (C), such that the first portion and the second portion constitute longitudinally different parts of a longitudinally heterogeneous filament (F) encompassed by the capillary (C); and extraction of the filament (F) from the capillary (C) thus laying it as a portion of a printed layer.

A support material for use in an additive manufacturing system includes a copolymer of vinyl pyrrolidone (VP) monomers and elastomeric monomers. The elastomeric monomers and the VP monomers are covalently bonded and copolymerized. The support material is thermally stable even at temperatures above 80° C. and is disintegrable in aqueous solutions such as tap water.

Provided is a material set for forming a three-dimensional object, the material set including: a first liquid material for forming a three-dimensional object; and a second liquid material for forming a three-dimensional object, wherein the first liquid material contains a solvent, an organic compound A, and inorganic particles, and wherein the second liquid material contains an organic compound B having reactivity with the organic compound A.

The present invention relates to a solid form, particularly to a 3D-printed immediate release solid dosage form (e.g. based on a pharmaceutical, nutraceutical, or food supplement composition). To overcome some of the solubility and disintegration problems inherited by 3D-printed solid dosage forms, the solid form comprises one or more channels, generally in the form of tubular passages or grooves, through the body of the solid form or the surface thereof.

A polymeric blend includes a blend of polyvinylpyrrolidone (PVP) polymers. The polymeric material includes a blend of at least two PVP polymers wherein at least one of the PVP polymers has an average molecular weight of about 40,000 daltons or greater. The support material can be thermally stable at temperatures above 80 C. The support material is disintegrable in aqueous solutions such as tap water.

Provided herein are devices and systems for depositing a material or manufacturing a product, such as a pharmaceutical dosage form, by additive manufacturing. Further provided are methods of using the devices and systems, as well as methods of manufacturing a product, such as a pharmaceutical dosage form, by additive manufacturing. In certain embodiments, the device includes a material supply system configured to melt an pressurized a material, a pressure sensor configured to detect a pressure of the material within the device, and a control switch comprising a sealing needle operable in an open position and closed position. The sealing needle extends through a feed channel containing the material and includes a taper end, wherein the tapered end of the sealing needle engages a tapered inner surface of a nozzle to inhibit flow of the material through the nozzle when the sealing needle is in the closed position.