A method of forming a three-dimensional object, is carried out by (a) providing a carrier and a build plate, the build plate comprising a semipermeable member, the semipermeable member comprising a build surface with the build surface and the carrier defining a build region therebetween, and with the build surface in fluid communication by way of the semipermeable member with a source of polymerization inhibitor; (b) filling the build region with a polymerizable liquid, the polymerizable liquid contacting the build surface, (c) irradiating the build region through the build plate to produce a solid polymerized region in the build region, while forming or maintaining a liquid film release layer comprised of the polymerizable liquid formed between the solid polymerized region and the build surface, wherein the polymerization of which liquid film is inhibited by the polymerization inhibitor; and (d) advancing the carrier with the polymerized region adhered thereto away from the build surface on the build plate to create a subsequent build region between the polymerized region and the build surface while concurrently filling the subsequent build region with polymerizable liquid as in step (b). Apparatus for carrying out the method is also described.

A hydrochromic polydiacetylene polymer patch and a method of manufacturing the same are provided. The hydrochromic polymer patch comprises a polymer matrix; and polydiacetylene present in the polymer matrix. The polydiacetylene has an ionic functional group in the repeating unit thereof. The ionic functional group is R.sup.M.sup.+ or R.sup.+X.sup.. R.sup. is a carboxylate anion, M.sup.+ is an alkali metal cation, and R.sup.+ is a quaternary ammonium group, and X.sup. is F.sup., Cl.sup., Br.sup., I.sup., PF.sub.6.sup., BF.sub.4.sup., bis(trifluoromethane)sulfonimide (Tf.sub.2N.sup.), trifluoromethanesulfonate (TfO.sup.), SCN.sup., or CH.sub.3COO.sup..

A system for making three dimensional objects. The system may have a frame, a build platform movably coupled to the frame, a vat removably secured so that the build platform may be lowered within the vat, and a movable radiation source capable of movement along an x and y-axis. The vat may have a radiation permeable flat bottom. The build platform may have a work surface disposed thereon. There may be at least one stepper motor capable of moving the radiation source, the build platform, or both the radiation source and the build platform. There may also be a power source, a data reader device and or computer communication device, and a microcontroller in communication with the at least one stepper motor and at least one of the data reader device or computer communication device.

A polymer composition containing a polyoxymethylene polymer having low shrinkage characteristics and/or an expanded processing window is disclosed. The polymer composition is particularly well suited for use in three-dimensional printing systems, such as printers that use filament fusion technology. The polymer composition, for instance, can be a feed material in the form of a filament or polymeric pellets. The feed material can be placed in a printer cartridge for insertion into a three-dimensional printing system. In accordance with the present disclosure, a polyoxymethylene polymer is combined with one or more dimensional stabilizing agents for dramatically improving the processing characteristics of the polymer.

The present disclosure provides a photopolymerizable composition. The photopolymerizable composition includes at least one polypropylene oxide component and an initiator, plus optionally a urethane component, a multifunctional reactive diluent, and/or an inhibitor. The present disclosure also provides an article including the reaction product of the photopolymerizable composition. Typically, the article exhibits an elongation at break of 30% or greater. Further, the present disclosure provides a method of making an article. The method includes (i) providing a photopolymerizable composition and (ii) selectively curing the photopolymerizable composition to form an article. The method optionally also includes (iii) curing unpolymerized polypropylene oxide component, urethane component and/or multifunctional reactive diluent remaining after step (ii). Further, methods are provided, including receiving, by a manufacturing device having one or more processors, a digital object comprising data specifying an article; and generating, with the manufacturing device by an additive manufacturing process, the article based on the digital object. A system is also provided, including a display that displays a 3D model of an article; and one or more processors that, in response to the 3D model selected by a user, cause a 3D printer to create a physical object of an article.

The present invention provides a non-porous, breathable and waterproof transparent plastic film on a plastic substrate and methods for fabricating the same. The film includes a thermoplastic polyester resin, an amphiphilic modifier having a hydrophilic segment that acts as a channel for water vapor transmission through the film connected to a hydrophobic segment that anchors the amphiphilic modifier to a portion of the polyurethane base resin and a compatibilizer. The resultant non-porous, breathable and waterproof transparent plastic film has a water vapor transmission rate (WVTR) or breathability of not less than 250 g/m.sup.2/24 hr according to ASTM E96B, and having at least 90% of the transmittance. They are also resistant to liquid penetration and micro-contaminants such as bacteria and virus, making them suitable for broad applications in medical, healthcare and food packaging industries.

A method for universal contactless printing comprises depositing a first droplet into a sound field, curing the droplet to form a cured droplet, depositing a second droplet, and securing the second droplet to previously cured droplet by curing the second droplet. The method of contactless printing can be repeated to form a complex three-dimensional structure. The first droplet that is deposited can be secured to a moveable structure by curing the first droplet to the moveable structure. The moveable structure can be moved to place a next droplet to be deposited and cured.

A method of fabricating an extended release subcutaneous medicinal dosage implant system which includes an implant fabricated from a highly homogeneously mixed composition including a medicinal agent in combination with release controlling polymers which include poly (DL-lactide) and polycaprolactone. In one implementation for treating an opioid disease, the formulation composition includes naltrexone at 40 weight percent, poly (DL-lactide) in the approximate range between 36 and 46.4 weight percent, and polycaprolactone in the approximate range between 24 and 11.6 weight percent. In addition, in order to provide anti-biofouling quality and prevent foreign body adsorption/interaction with the material of the implant, polyethylene glycol is added in a preferred content of 2.0%. The manufacturing process includes hot melt extrusion and a mini jet based implant formation stage with the optimized process space were the temperature of the process ranges from 170? C.-180? C., mixing time through the HME process ranging from 8 minutes to 12 minutes, and injection time ranging from 8 seconds to 12 seconds. The resulting implants have a uniquely shaped free of defects bio absorbable solid body.

A process for the manufacture of semi-plastic pharmaceutical unit doses using a rotary moulding machine and semi-plastic pharmaceutical dosage units obtained by this process.

Described is a multilayer glove (100) comprising at least one inner layer (230) having a thickness t.sub.i, a top surface, and a bottom surface, the bottom surface facing a hand of a user when wearing the glove; at least one inner protective layer (225) having a thickness t.sub.ip, a top surface, and a bottom surface, the bottom surface abutting the top surface of the inner layer (230); an outer layer (210) having a thickness t.sub.o, a top surface, and a bottom surface, the bottom surface facing a hand of a user when wearing the glove; at least one outer protective layer (215) having a thickness t.sub.op, a top surface, and a bottom surface, the top surface abutting the bottom surface of the outer layer (210); and at least one indicator layer (220) having a thickness t.sub.c disposed between the top surface of the inner protective layer (225) and the bottom surface of the outer protective layer (215), wherein the indicator layer comprises at least one pH indicator that generates a color visible at the top surface of the outer layer when the indicator layer is exposed to an aqueous medium, wherein the sum of t.sub.o, each t.sub.op, each t.sub.c, each t.sub.ip, and each t.sub.i defines a total thickness T.