An extrudable hydrogel composition useful for making a three-dimensional organ construct includes a cross-linkable prepolymer, a post-deposition crosslinking group, optionally, an initiator that catalyzes the reaction between the prepolymer and said the crosslinking group; live cells (e.g., plant, animal, or microbial cells), optionally at least one growth factor, and optionally water to balance. Methods of using the same and products so made are also described.

Provided is a three-dimensional model including: a three-dimensional body formed of a hydrogel containing a water-based solvent and a polymer; and a coating film coating the surface of the three-dimensional body and formed of a hydrogel containing a water-based solvent and a polymer.

Described herein are improvements to bioprinting technology that facilitate automation of tissue and organ fabrication processes.

A bioprinter for fabricating three-dimensional (3D) cell constructs, the bioprinter comprising one or more holding reservoirs for holding a fluid sample; a printstage for holding a sample container and supporting a substrate on which a 3D cell construct is to be printed; a sample loading system in fluid communication with the one or more holding reservoirs, the sample loading system configured to load a sample from a sample container into the one or more holding reservoirs; a pump in fluid communication with the sample loading system, the pump configured to draw the sample out of a sample container and pump the sample into the one or more holding reservoirs; and a droplet dispensing system in fluid communication with the one or more reservoirs, the droplet dispensing system configured to print sample droplets from the one or more reservoirs onto a substrate supported by the printstage.

A solid freeform fabrication object includes a hydrogel including a polymer, water, and a coloring material inclusion substance.

The present application relates to a method for selecting an injection-molded article and a method for manufacturing an injection-molded article. An injection-molded article having excellent crack stability can be produced using the material selected using the described selection method without having to manufacture test articles through injection molding

An ultrasound probe of the present invention has a piezoelectric element and a backing material disposed on one direction side with respect to the piezoelectric element, the backing material containing heat conductive particles. The backing material has a heat conductivity of 2.0 W/mk or more, and the content of the heat conductive particles is less than 30 vol % based on the total volume of the backing material.

The present invention relates a setting method for a conducting element of an electrochemical test strip and electrochemical test strip thereof. An inspection body is formed by injection molding polymer plastic materials to coat with the plurality of conducting elements, and an external contact surface on an information outputting end of the conducting element is exposed from an inspection slot of the inspection body, so that the information outputting end of the conducting element is extended from the inspection body. Eventually, the information outputting end is bent to fix on a surface of the inspection body. The present invention is not complex and has more precision and convenience, and the manufacturing cost can be reduced efficiently, so that wide application can be expected in the near future.

Described herein are apparatuses, systems, and methods for fabricating tissue constructs, such as by fabricating perfusable tissue constructs by embedding a sacrificial material into a composite matrix yield stress support bath. A composite matrix bath can include a microgel filler and a hydrogel precursor. An extrusion tip can be used for embedded printing of perfusable tissue constructs by disposing sacrificial material into the composite matrix bath while the extrusion tip travels along a predefined course through the composite matrix bath. This sacrificial material can be the printed tissue construct or can be removed to render the matrix bath a perfusable tissue construct. The composite matrix bath can include acellular or cell-laden hydrogels. The sacrificial material can include a salt and a physiological buffer or a non-cytotoxic porogen material. The hydrogel precursor can include at least one of gellan and gelatin. Cross-linking can be carried out chemically, thermally, enzymatically, or physically.

A process for producing a 3D tissue culture model by (a) printing a drop of bio-ink to a substrate; (b) printing a drop of activator to the drop of bio-ink to form a hydrogel droplet; (c) repeating steps (a) and (b) in any order to form a hydrogel mold adapted to receive a drop containing cells; (d) printing a drop containing cells to the hydrogel mold; and (e) repeating steps (a) and (b) in any order to form a 3D tissue culture model comprising the cells encapsulated in the hydrogel mold.