Method of analysis. In the method, a first emulsion and a second emulsion substantially separated from one another by a spacer fluid may be formed. The first emulsion, the spacer fluid, and the second emulsion may be flowed in a channel from a fluid inlet to a fluid outlet of a heating and cooling station having two or more temperature-controlled zones, such that each emulsion is thermally cycled to promote amplification of a nucleic acid target in droplets of the emulsion. Amplification data may be collected from individual droplets of each emulsion downstream of the heating and cooling station. A level of the nucleic acid target present in each emulsion may be determined based on the amplification data collected from the individual droplets of the emulsion.

A composite structure with high pressure resistance that is suitable for a flow channel is produced by reducing the number of components while maintaining the excellent chemical resistance and high stress tolerance inherent to a glass substrate and a resin substrate. A glass substrate surface is modified with a hydrolyzable silicon compound, and the glass substrate is brought into contact with the resin substrate. Subsequently, the contact surface between the glass substrate and the resin substrate is heated to a temperature from the glass transition temperature to the pyrolysis temperature of the resin substrate, eliminating gaps between the glass substrate and the resin substrate to bring them into close contact with each other, and causing chemical binding or anchor effects between the glass substrate and the resin substrate via the hydrolyzable silicon compound. Thus, the glass substrate and the resin substrate are firmly fixed to each other.

Methods for fabricating three-dimensional microstructures are provided. The method includes disposing a reflow material on a mold, heating the reflow material, and creating a pressure gradient across the reflow material to reflow the material towards a bottom surface of the mold. The mold includes a molding region, a boundary region, and a thermal-isolating region disposed therebetween. The molding region includes a cavity and a projection projecting upwards from a bottom surface of the cavity. The thermal-isolating region includes at least one pocket formed adjacent to and along a perimeter of the cavity of the molding region. During heating, the temperature of the molding region is higher than that of the boundary region and the thermal-isolating region controls the thermal conductivity and mass therebetween. The material reflows towards the bottom surface of the cavity and the protrusion helps shapes the reflow material to form a substantially symmetrical three-dimensional microstructure.

A gauge having a housing formed of a polymer material and one or more electrical feedthrough pins disposed in the housing. The electrical feedthrough pins can be oriented substantially perpendicular to each other and have complex shapes.

Replaceable shaving assemblies are disclosed that include a blade unit, an interface element configured to removeably connect the blade unit to a handle, on which the blade unit is pivotably mounted, and a return element disposed between the blade unit and interface element. The return element serves as interface piece, connector and pivot all in one. Shaving systems including such shaving assemblies are also disclosed, as are methods of using such shaving systems.

A form for a vehicle component includes a commingled fiber bundle composed of thermoplastic fibers and a reinforcement fiber. The reinforcement fiber being glass fibers, aramid fibers, carbon fibers, or a combination thereof. The commingled fiber bundle is laid out in a two-dimensional base layer that defines a shape of the form. An optical fiber is stitched to the commingled fiber bundle. A method of forming a unitary reinforced composite component having a sensor system includes the form being placed onto a mold platen. The preform is heated to promote fusion of the thermoplastic fibers therein. The preform is cooled until solidified with contours of the component. The vehicle component is then removed from the mold platen.

A method of manufacturing a radiation detector includes adding a fluorescing medium to an additive manufacturing consumable to form a consumable mixture; additively manufacturing a plastic scintillator from the consumable mixture; and coupling the plastic scintillator to a light-to-current device, thereby forming an additively manufactured plastic scintillation detector.

An inserter apparatus (e.g., a continuous analyte monitoring inserter apparatus) includes an outer member; an inner member; a transmitter carrier configured to support a transmitter and biosensor assembly during insertion of a biosensor, the transmitter carrier including a bias member; and a pivot member configured to pivot at times relative to the transmitter carrier and support an insertion device during biosensor insertion. The outer member is configured to press the bias member against the pivot member during insertion of the biosensor. During a first stroke portion of the insertion apparatus, the pivot member is prevented from pivoting. In a second stroke portion, pivoting is allowed, and the bias member causes, pivoting of the pivot member and retraction of the insertion device. Other systems and methods embodiments are provided.

One aspect relates to a body, including at least one first polymer segment having a porosity p1 and an electrical conductivity c1, and at least one further polymer segment being in seamless contact with the at least one first polymer segment and having a porosity p2p1 and an electrical conductivity c2c1. One aspect also relates to a process for the preparation of a body, to a body obtainable by such a process, to the use of a body for electrophysical measurements or as a biosensor and to a therapeutic current delivery or current receiving system comprising the body.

A contact detection device detects pressure over a wide range, be applied to even a three-dimensional structure, and detect predetermined contact pressure or more. A volume space 4 is between a base 1 that is composed of a foamed synthetic resin 10 with a particular shape and the foamed synthetic resin body 10 that is composed of the foamed synthetic resin with a particular shape and covers the foamed synthetic resin body 10. The volume space 4 is on either or both of the base 1 and the foamed synthetic resin 10. Air in the volume space 4 is prevented from leaking trough the base 1 and the foamed synthetic resin 10 to open air. At least one flow sensor 70 detects flow rate (liter/second) of air that flows from the volume space 4 to open air.