In sterile, additive manufacturing wherein one lamella is successively built upon an underlying lamella until an object is completed, a sterile manufacturing environment is provided. A major chamber large enough to accommodate the manufactured object has sterile accordion pleated sidewalls and a sterile top closed with flap valves. A minor chamber for supporting the nozzles positioned above the major chamber has similar valves in corresponding positions. Nozzles for material deposition penetrate the pair of valves to block air and particles from entry into the major chamber where the nozzles make layer by layer deposition of the object using XY areawise nozzle motion relative to the object as well as Z nozzle vertical motion with the major chamber expanding as the object is formed.

The present disclosure relates to a method of fabricating a composite structure using a pre-cured composite stiffener and a dry fabric component. In one example, the method includes the steps of: wrapping an adhesive film and a resin film around an edge of said pre-cured composite stiffener; inserting the edge of said pre-cured composite stiffener into a clevis of a dry fabric component to form a composite structure assembly; securing the pre-cured composite stiffener substantially perpendicularly to the base portion of the dry fabric component; and starting a consolidated infusion and cure process. The consolidated infusion and cure process applies a first temperature to the composite structure assembly for a first predetermined period of time to infuse the dry fabric component, and the increases the first temperature to a second temperature for a second predetermined period of time to cure the composite structure assembly.

Disclosed herein, amongst other things, is a molding system (100) comprising control structure that includes a mold (120) that is configured to mold a molded article (180), a controller (170) with which to control the operation of the molding structure, and a vision system (174) with which to appreciate a parameter of the molded article (180) for control of molding system (100).

The invention relates to a dosage form that is thermoformed without discoloration and is safeguarded from abuse, comprising at least one synthetic or natural polymer having a breaking strength of at least 500 N in addition to one or more active substances that could be subject to abuse. The invention also relates to a corresponding method for producing said dosage form.

A fishing rod that includes an elongated, tapered rod blank at least a portion of which is quadrilateral in cross section, the quadrilateral portion of the rod blank diminishing in cross-sectional area toward a tip end of the rod blank, the quadrilateral portion of the rod blank comprising a sandwich-structured composite of a core disposed between facings, the core less dense than the facings, the quadrilateral portion of rod blank less stiff in a casting direction than transverse to the casting direction; fishing line guides mounted at intervals along the length of the rod blank; a reel seat mounted at the base end of the rod blank; and a handle mounted at the base end of the rod blank adjacent to the reel seat.

A centralizer can be produced from a process comprising forming a plurality of composite bow spring from a fiber and a resin, curing the composite bow springs in a desired shape to form a plurality of cured bow springs, disposing a first portion of a resin-wetted fiber about a cylindrical mandrel to form a plurality of collars, disposing the plurality of cured bow springs onto the mandrel with the bow spring ends in contact with the first portion of resin-wetted fiber, disposing a second portion of the resin-wetted fiber about the cylindrical mandrel, curing the collars to form a cured centralizer, and pressing the mandrel out of the cured centralizer.

The invention relates to a dosage form comprising a physiologically effective amount of a physiologically active substance (A), a synthetic, semi-synthetic or natural polymer (C), optionally one or more physiologically acceptable auxiliary substances (B) and optionally a synthetic, semi-synthetic or natural wax (D), wherein the dosage form exhibits a resistance to crushing of at least 400 N and wherein under physiological conditions the release of the physiologically active substance (A) from the dosage form is at least partially delayed.

A three-dimensional structure is formed when layers of a material are deposited onto a substrate and scanned with a high energy beam to at least partially melt each layer of the material. Upon scanning the layers at predetermined locations at least a first segment overlapping a second segment and underlapping a third segment is formed.

A dispenser for additive material manufacturing having a sealed cartridge with sterile material to be dispensed. The cartridge is removable from a support housing that is movable during deposition of additive material. A nozzle extending from a heated plenum below the cartridge is inserted into a sealed variable volume enclosure supporting the article being manufactured on a movable table within the enclosure.

A shape-shifting structured lattice comprises a printed lattice including printed ribs joined at nodes. Each printed rib has a predetermined sweep angle {tilde over ()}.sub.i between adjacent nodes and a bilayer structure including at least two printed filaments in contact along a length thereof. The at least two printed filaments comprise different linear coefficients of thermal expansion and/or different values of elastic modulus. When exposed to a stimulus, the printed lattice adopts a predetermined three-dimensional geometry.