The present invention relates to the treatment or prevention of skeletal disorders, in particular skeletal diseases, developed by patients that display abnormal increased activation of the fibroblast growth factor receptor 3 (FGFR3), in particular by expression of a constitutively activated mutant of FGFR3.

It is described a metamaterial sound insulation device, with improved efficiency in dampening sound transmission across it compared to a traditional sound insulation device having comparable size and weight. The device is especially adapted for sound insulation in the automotive field.

A multi-layer ballistic woven fabric, including an upper woven layer having upper warp yarns and upper weft yarns that are interwoven together to form the upper woven layer. The multi-layer ballistic woven fabric also includes a lower woven layer having lower warp yarns and lower weft yarns that are interwoven together, and a plurality of securing yarns, each securing yarn interwoven with at least some of the upper yarns and some of the lower yarns so as to secure the upper and lower woven layers together. At least one of the securing yarns is woven underneath a first lower weft yarn, then above a second upper weft yarn adjacent the first lower weft yarn, then underneath a third lower weft yarn adjacent the second upper weft yarn and then above a fourth upper weft yarn adjacent the third lower weft yarn. The multi-layer ballistic woven fabric is formed by interweaving the securing yarns with the warp yarns and weft yarns as the upper woven layer and lower woven layer are made.

A vehicle sandwich component with a layered construction having a honeycomb structure. The honeycomb structure may have a first lower honeycomb layer and a second upper honeycomb layer, the first lower honeycomb layer has at least one edge portion protruding laterally in the transverse direction beyond the second upper honeycomb layer, and a central honeycomb layer region or compression region which has a reduced thickness, achieved by compression, in relation to the edge portion and on which the second upper honeycomb layer is provided. Also, method for producing a vehicle-sandwich component of this type.

A composite product substantially reduced the impact force imposed by hard impactor which travelled at the speed in the range of 400 m/s to 1400 m/s simultaneously damping the vibrations and shocks appeared therein is disclosed. At the same time it is light weight with the weight lower than that of 22 to 38 kg/m2and is flexible to adopt the shape suitable for the end applications. A method of manufacturing the composite product of the invention is also disclosed.

A laminated glass provided in an automobile door panel including two panel boards facing each other and seal members provided on facing surfaces of the panel boards at regions along a beltline, the laminated glass being openable and closable by being provided between the two panel boards so as to slide between the seal members, the laminated glass includes: a laminated glass main body including at least two glass plates and an interlayer film sandwiched between the glass plates and having a storage modulus G of 1.5×10.sup.6 Pa or more; and a viscoelastic member provided on a surface of the laminated glass main body, the viscoelastic member abutting on the seal member or the panel board and sealing a gap between the seal member or the panel board and the laminated glass main body, at a closed time of the laminated glass.

The present disclosure relates to the technical field of composite structures, and provides a polyurethane composite floor, and a method for manufacturing the polyurethane composite floor. The polyurethane composite floor includes a foamed layer and a decorative layer arranged on the foamed layer, the foamed layer comprises an intermediate core material, two braided fibre layers respectively arranged on a top portion and a lower portion of the intermediate core material, the braided fibre layer arranged on the top end of the intermediate core material is defined as an upper braided fibre layer, the braided fibre layer arranged on the lower end of the intermediate core material is defined as a lower braided fibre layer, the intermediate core material defines a plurality of filling gaps, each filling gap is filled with a rigid polyurethane foam. The present disclosure provides the polyurethane composite floor, and the method for manufacturing the polyurethane composite floor, the polyurethane composite floor has the advantages of low cost, strong weather resistance, and wide adaptability, and the polyurethane composite floor may be integrally-formed by a mold, the chemical internal energies of self-reactions of the rubber elastomer layer and the polyurethane foaming material can be used to catalyze and cure mutually, which greatly saves the production energy consumption, and avoids the use of glue, the polyurethane composite floor is much more environmentally friendly and durable, and the processing process is simple.

Precursors and methods for manufacturing perforated composite parts are disclosed. An exemplary precursor (19) comprises structural fibres (24,28) embedded in a cured matrix material (24,26) and interposed between two removable plies (20). The precursor may also comprise a sacrificial fibre (28) extending through the removable plies (20), the matrix material (24,26) and between the structural fibres (24,28). An exemplary method comprises removing the removable plies (20) from the precursor (19) and removing the sacrificial fibre (28) from the precursor after removing the removable plies to form a through hole in the precursor (19) at a location of the sacrificial fibre (28).

A stretch laminate includes a first layer including an elastomer film, the first layer having a surface, and a second layer including a nonwoven material, the second layer having a surface that is attached to the surface of the first layer. The tensile behavior in the transverse direction of the stretch laminate is within about 2.5 N/cm of the tensile behavior in the transverse direction of the film at an engineering strain of about 1.5, and exists independent of mechanical activation. A method of making the stretch laminate and an absorbent article having at least one region defined by the stretch laminate are also provided.

A method for producing a decorated plastic molded article with the steps: a) providing a base body made of a fiber composite plastic b) providing a decorative film; c) heating the base body; d) joining the base body and the decorative film in a mold.