A manipulation assembly includes a delivery catheter having a lumen extending therethrough and a deployment catheter positioned within the delivery catheter. The deployment catheter is independently manipulatable with respect to the delivery catheter. The assembly further includes a visualization element extendable distally beyond the deployment catheter and an ablation probe comprising an energy transmitting surface positionable to ablate tissue adjacent to a distal end of the ablation probe. The ablation probe is extendable distally beyond the deployment catheter.

This method is for calibrating an optical scanning apparatus that includes an optical fiber with a tip supported to allow vibration and an actuator that drives the tip of the optical fiber in a direction perpendicular to the optical axis of the optical fiber. The method includes arranging a position sensitive detector that detects a position of emitted light from the tip of the optical fiber (step S02) and detecting the position of the emitted light with the position sensitive detector while supplying light to the optical fiber and driving the tip of the optical fiber (step S03). The step of detecting (step S03) is performed using an interference fringe reducer that reduces interference fringes occurring along an optical path reaching the position sensitive detector.

A biological observation system includes: a light source apparatus configured to supply a first illuminating light, and a second illuminating light, while switching between the first illuminating light and the second illuminating light; an image pickup device configured to receive light from an object at each of a plurality of pixels having different sensitivities, and picks up an image; a color separation processing portion configured to separate, from respective color components, a color component obtained when an image of light of a predetermined wavelength band is picked up by a pixel having the greatest sensitivity to the light in the predetermined wavelength band; and a control portion configured to cause different processing to be performed between a case where an inputted image pickup signal corresponds to the first illuminating light and a case where an inputted image pickup signal corresponds to the second illuminating light.

A focus control device includes a processor including hardware, the processor being configured to implement: an area setting process that sets a plurality of areas, each including a plurality of pixels, on a captured image acquired by an imaging section, an evaluation value calculation process that calculates an AF (Autofocus) evaluation value for each of the plurality of set areas, a bright spot influence rate calculation process that calculates a bright spot influence rate for each of the plurality of set areas, based on whether or not the area includes a high luminance portion determined to have a size equal to or larger than a given size, and focus control based on the AF evaluation value and the bright spot influence rate.

A focus control device includes a processor including hardware, the processor being configured to implement: an area setting process that sets a plurality of areas, each including a plurality of pixels, on a captured image acquired by an imaging section, an evaluation value calculation process that calculates an AF (Autofocus) evaluation value for each of the plurality of set areas, a bright spot influence rate calculation process that calculates a bright spot influence rate for each of the plurality of set areas, based on whether or not the area includes a high luminance portion determined to have a size equal to or larger than a given size, and focus control based on the AF evaluation value and the bright spot influence rate.

An endoscope device includes: an normal light image acquisition unit that acquires an normal light image; a special light image acquisition unit that acquires a special light image; a blended image generation unit that generates a blend image by combining one color component image from among a plurality of color component images constituting the normal light image and the special light image; and a superimposed image generation unit that generates a color superimposed image by combining the blended image with another color component image. The blended image generation unit generates the blended image by replacing a part of the pixels of the one color component image with the corresponding pixels of the special light image such that they are blended in a substantially uniform distribution over the entire blended image.

Provided is a biological observation apparatus including: illuminating portions that irradiate biological tissue with illumination light including light in R, G, and B regions, respectively; an image acquisition portion that acquires image signals from reflected light of the illumination light coming from the biological tissue; narrow-band-light generating portions that are disposed in the illuminating portions or the image acquisition portion and that, in wavelength bands of the illumination light, generate two narrow-band beams for at least one of the R, G, and B wavelength bands constituting the illumination light, on either side of a central wavelength of that wavelength band; and an image-generating portion that generates an image on the basis of two or more types of the image signals obtained from the reflected light including two or more narrow bands acquired by the image acquisition portion.

An image pickup apparatus includes: an image pickup device that includes a light receiving surface, an opposite surface, a light receiving portion, and external electrodes connected to the light receiving portion; and a wiring board that includes a first main surface, a second man surface, and a wiring portion provided with first bonding electrodes bonded to the external electrodes, wherein the first main surface of the wiring portion is arranged at a first angle θ1 equal to or smaller than 90 degrees relative to the opposite surface, the wiring board includes a reinforced portion and a folded portion bent at the first angle θ1 between the reinforced portion and the wiring portion, and the second main surface of the reinforced portion is fixed to the opposite surface of the image pickup device.

An image pickup apparatus includes: an image pickup device that includes a light receiving surface, an opposite surface, a light receiving portion, and external electrodes connected to the light receiving portion; and a wiring board that includes a first main surface, a second man surface, and a wiring portion provided with first bonding electrodes bonded to the external electrodes, wherein the first main surface of the wiring portion is arranged at a first angle θ1 equal to or smaller than 90 degrees relative to the opposite surface, the wiring board includes a reinforced portion and a folded portion bent at the first angle θ1 between the reinforced portion and the wiring portion, and the second main surface of the reinforced portion is fixed to the opposite surface of the image pickup device.

A capsule endoscope configured to be introduced into a subject is provided. The capsule endoscope includes: a magnetic switch configured to operate depending on a magnetic field externally applied; a first device including an inductor and configured to execute a predetermined function; a second device including no inductor and configured to execute a function different from that of the first device; and a controller configured to drive the second device without driving the first device when the magnetic field is applied to the magnetic switch.