An optical system for a stereo video endoscope, a stereo video endoscope and a method for operating an optical system. The optical system includes a distal optical assembly and a proximal optical assembly with a left lens system channel and a right lens system channel. The distal optical assembly couples light incident from an object space into the left lens system channel and into the right lens system channel of the proximal optical assembly. The distal optical assembly is an optical assembly with an adjustable focal length, wherein a change in the focal length causes a displacement of an axis intersection point in the object space.

A guidance apparatus includes: a magnetic field generator configured to generate a magnetic field that acts on a magnet; a magnetic field shielding material configured to shield the magnetic field generated by the magnetic field generator; an operation input device configured to receive an input of at least one of a target position and a target posture for guiding a position and a posture of a capsule medical apparatus; and a controller configured to control the magnetic field generator to generate a magnetic field that has been corrected to offset or reduce a deviation amount of the position or the posture of the capsule medical apparatus with respect to the target position or the target posture, caused by distortion, due to the magnetic field shielding material, of a magnetic field for guiding the capsule medical apparatus to at least one of the target position and the target posture.

Described embodiments include a capsule, including a cyclically everting sleeve shaped to define a sleeve interior, a fluid, configured to facilitate the everting of the sleeve, contained within the sleeve interior, and a plurality of electrically-conductive coils coupled to the sleeve. The coils are configured to, when at least two of the coils are magnetized, advance the capsule within a lumen by applying an everting force to the sleeve. Other embodiments are also described.

A method of analysis using mass spectrometry and/or ion mobility spectrometry is disclosed comprising: (a) using a first device to generate smoke, aerosol or vapour from a target in vitro or ex vivo cell population; (b) mass analysing and/or ion mobility analysing said smoke, aerosol or vapour, or ions derived therefrom, in order to obtain spectrometric data; and (c) analysing said spectrometric data in order to identify and/or characterise said target cell population or one or more cells and/or compounds present in said target cell population.

A method for enhanced surgical navigation, and a system performing the method and displaying graphical user interfaces associated with the method. A 3D spatial map of a surgical site is generated using a 3D endoscope including a camera source and an IR scan source. The method includes detecting a needle tip protruding from an anatomy and determining a needle protrusion distance corresponding to a distance between the needle tip and a surface of the anatomy using the 3D spatial map. A position of a surgical tool in the 3D spatial map is detected and a determination is made by the system indicative of whether the needle protrusion distance is sufficient for grasping by the surgical tool. A warning is generated when it is determined that the needle protrusion distance is not sufficient for grasping by the surgical tool.

A system may comprise a catheter including a wall having an inner surface defining a main lumen. The system may also comprise a device including an elongate flexible shaft configured to be slideably inserted within the catheter main lumen and a structure disposed around an outer surface of the elongate flexible shaft. The structure may be configured to engage with a plurality of flat surfaces comprising a portion of the inner surface to prevent rotation of the device within the main lumen.

A system may comprise a first catheter having a first steerable segment and a second catheter disposed within the first catheter. The second catheter may have a second steerable segment. The system may also comprise an imaging element supported at a distal end of the second catheter, a coil reference sensor supported at a distal portion of the second catheter, and a processor in electrical communication with the coil reference sensor. The processor may be configured to determine a position of a distal portion of the first catheter with reference to the coil reference sensor.

A system may comprise a first catheter having a first steerable segment and a second catheter disposed within the first catheter. The second catheter may have a second steerable segment. The system may also comprise an imaging element supported at a distal end of the second catheter, a coil reference sensor supported at a distal portion of the second catheter, and a processor in electrical communication with the coil reference sensor. The processor may be configured to determine a position of a distal portion of the first catheter with reference to the coil reference sensor.

Improved fluoresced imaging (FI) endoscope devices and systems are provided to enhance use of endoscopes with FI and visible light capabilities. An endoscope device is provided for endoscopy imaging in a white light and a fluoresced light mode. A relay system includes an opposing pair of rod lens assemblies positioned symmetrically with respect to a central airspace. The rod lens assemblies include a meniscus lens positioned immediately adjacent to a central airspace and with the convex surface facing the airspace, a first lens having positive power with a convex face positioned adjacent to the inner face of the meniscus lens, a rod lens adjacent to the first lens having positive power and an outer optical manipulating structure selected from various designs providing chromatic aberration correction.

Photobiomodulation can be used to treat disorders of the gastrointestinal system. The photobiomodulation can be delivered by an intraluminal device (which can be within the gastrointestinal system) that includes at least one light delivery device configured to provide photobiomodulation; at least one photodetector device to measure reflectance based on the photobiomodulation; a processor to receive a reflectance signal from the at least one photodetector device based on the reflectance measured by the at least one photodetector device and process the reflectance signal; and a wireless transceiver coupled to the processor to transmit at least a portion of the processed reflectance signal. The wireless transceiver can communicate with an external device that includes a wireless transceiver to receive the at least the portion of the processed reflectance signal.