A contact lens includes a contact lens body and a glucose detection sheet disposed on the contact lens body. The glucose detection sheet includes a glucose recognition layer, a photonic crystal array is provided in the glucose recognition layer, and the glucose recognition layer is configured to recognize glucose.

Systems, methods, and devices for directed to duplex imaging techniques for combining high-resolution surface images obtained with a Scanning Fiber Endoscope (SFE), and high-resolution penetrating OCT images obtained through Optical Coherence Tomography (OCT), from a SFE, and interleaving frames to improve resolution and identify below surface information of biological structures.

Systems, methods and software for scanning an ocular structure of an eye are provided. A method includes projecting a light onto the ocular structure, and scanning, by natural movements of the living eye, the light in a region of the living eye. Applicable ocular structures can include an ocular surface, a cornea, a sclera, an iris, a crystalline lens, an ocular fundus, a retina, a choroid, and a vitreous humor. A system includes a light source to create light, and optics to focus the light from the light source onto the ocular structure and to collect secondary light coming from the eye towards a detector. The system also includes a tracking system to register positions of the eye at different times, and a computer system to receive signals coupled from the tracking system representative of eye positions at different times and associate the signals with the tracking position.

Systems and methods are provided for performing optical coherence tomography angiography for the rapid generation of en face images. According to one example embodiment, differential interferograms obtained using a spectral domain or swept source optical coherence tomography system are convolved with a Gabor filter, where the Gabor filter is computed according to an estimated surface depth of the tissue surface. The Gabor-convolved differential interferogram is processed to produce an en face image, without requiring the performing of a fast Fourier transform and k-space resampling. In another example embodiment, two interferograms are separately convolved with a Gabor filter, and the amplitudes of the Gabor-convolved interferograms are subtracted to generate a differential Gabor-convolved interferogram amplitude frame, which is then further processed to generate an en face image in the absence of performing a fast Fourier transform and k-space resampling. The example OCTA methods disclosed herein are shown to achieve faster data processing speeds compared to conventional OCTA algorithms.

In an aspect, a method for imaging a target comprises steps of: performing optical coherence tomography (OCT) scanning on the target with one or more beams of source light, the one or more beams of source light comprising a plurality of wavelengths; wherein performing OCT scanning comprises: providing the source light to a reference optical path and to a sample optical path, wherein providing the source light to a sample optical path comprises illuminating the target with the source light; and recording interference data corresponding to an interaction of a light from the reference optical path and a light from the sample optical path; processing the interference data; and identifying blood or one or more blood-features in the target based on an optical attenuation of light in or associated with the sample optical path by the blood or the one or more blood-features.

In the ophthalmic apparatus 1 of an aspect example, the image acquiring unit (the fundus camera unit 2, the OCT unit 100, the image data constructing unit 220) acquires an anterior segment image constructed based on data collected from an anterior segment of a subject's eye by OCT scanning. The part image identifying processor 231 performs identification of two or more part images respectively corresponding to two or more parts of the anterior segment from the anterior segment image acquired. The part image assessing processor 232 performs image quality assessment of each of the two or more part images. The anterior segment image assessing processor 233 performs image quality assessment of the anterior segment image based on two or more pieces of assessment data respectively obtained for the two or more part images.

The present invention relates to a contact lens for diagnosis and treatment of dry eye syndrome. The contact lens, according to the present invention, may diagnose dry eye syndrome by means of a change in an electric current occurring as a result of a field effect when a dry eye syndrome biomarker binds to a probe, and when dry eye syndrome is diagnosed, generates an electric current so that a gold film blocking a drug reservoir melts by the electric current, thereby enabling the release of a drug to be controlled.

An OCT apparatus processes an OCT signal based on reference light and measurement light with which a subject eye is irradiated to capture a tomographic image of a tissue of the subject eye. The OCT apparatus includes a controller. The controller captures a three-dimensional tomographic image of the tissue by irradiating a two-dimensional measurement region, which expands in a direction intersecting an optical axis of the measurement light, with the measurement light. The controller extracts a two-dimensional tomographic image from the three-dimensional tomographic image to display the two-dimensional tomographic image on a display unit. The controller sets an additional imaging position of a tomographic image in a state where the two-dimensional tomographic image is displayed on the display unit. The controller performs additional capturing of a tomographic image by irradiating the set additional imaging position with the measurement light.

A contact lens according to an embodiment of the present disclosure includes a lens section to be worn on an eyeball. The contact lens further includes a communication electrode, a sensor device, a controller, and a shield layer in the lens section. The controller supplies electric power to the communication electrode, and outputs a signal corresponding to information acquired by the sensor device to the communication electrode. The shield layer is provided at a position facing at least one of the sensor device, the controller, or the communication electrode.

An evaluation device for tear secretion uses an air nozzle and a thermal camera device to cause minor irritations to the eyes and record the temperature changes of the eyes to evaluate the quantity of the tear secretion and to determine whether the subject is able to perform reflex tearing normally or not.