A system comprising: a) a toilet comprising a toilet bowl for receiving excreta; b) a detection unit mounted to the toilet bowl and comprising: (i) one or more detectors selected from a group consisting of one or more laser triangulation sensors, an infrared sensing device and a Doppler velocimeter), (ii) a data processor, (iii) a data storage device, (iv) a wireless transmitter to transmit data from the detectors to a communications network and (v) a power source, wherein the one or more sensors are positioned measure characteristics of excreta deposited in the toilet bowl; and c) a computer configured to receive the data over the communications network and comprising memory including computer code to analyze the data and determine an amount of urine and/or feces deposited into the toilet bowl, and a processor to execute the code.

The present invention provides a method in which a quantitative and descriptive approach is used to adapt the food texture in the clinical management of dysphagia. There is provided a new index, ST index, and method of use for determining and modulating the physical characteristics of foods in a manner to allow the food composition at serving temperature to have a desired combination of firmness, adhesiveness, springiness and cohesiveness to overcome dysphagia-related problems.

In accordance with some non-limiting examples of the disclosed subject matter, an ingestible system configured to acquire physiological information from an interior of a subject is provided, comprising a substrate and at least one physiological sensor. The at least one physiological sensor can be coupled to the substrate and configured to capture physiological data from at least one of an internal area or an orientation in a digestive tract of the subject. The system can include a controller coupled to the substrate and configured to receive the physiological data and prepare the physiological data for one of transmission from the subject or analysis of the physiological data. The substrate, including the at least one physiological sensor and the controller coupled thereto can be configured to self-orient within the digestive tract of the subject, during ingestion of the system by the subject.

Systems and methods are provided to limit abdominal distension and alleviate uncomfortable side effects related to itin patients treated in hydrocolonic preparation units. Systems may comprise a water delivery unit comprising a controllable water supply, configured to introduce water controllably into the patient's large intestine, a drainage configured to drain, by gravity, the introduced water with contents of the patient's large intestine and a controller. The drainage comprises a drainage pipe and sensor(s) such as camera(s) configured to continuously measure the amount of drained water drained by the drainage pipe. The controller is configured to control the water introduction with respect to the measured amount of drained water, keeping an amount of water retained in the patient below a specified water retention threshold to reduce uncomfortable side effects of abdominal distension.

The present disclosure relates to gastrointestinal (GI) tract detection methods, devices and systems.

A capsule for traversing the gastrointestinal tract, including one or more compartments configured to sample the environment surrounding the capsule or configured to deliver content to the environment surrounding the capsule, an internal controller configured to activate the one or more compartments to sample or deliver, wherein the capsule includes a tracking system configured to identify the location of the capsule in real-time and activate a compartment when reaching a specific location in the gastrointestinal tract.

Devices and methods for delivering an ingestible medicament of a medicament tablet into the gastrointestinal tract of a user. A device according to the invention includes a vibrating ingestible capsule and a hollow medicament compartment housing. The vibrating capsule includes a housing, a vibrating agitator disposed within the housing, a power supply, and a control element. The hollow medicament compartment housing is associated with the housing of the capsule and includes at least one aperture. The hollow of the medicament compartment housing is configured to have the medicament tablet disposed therein. The aperture(s) are dimensioned to enable fluid communication the surrounding environment and the hollow.

This disclosure features methods and compositions for treating diseases of the gastrointestinal tract with a SMAD7 inhibitor.

Sampling systems that include an absorbent material a preservative, such as an analyte preservative, as well as related materials and methods, are disclosed.

An electronic device may include a display, a photoplethysmogram (PPG) sensor, a wireless communication circuit, a processor operatively connected to the display, the PPG sensor, and the wireless communication circuit, and a memory operatively connected to the processor. The electronic device implements the method, including monitoring blood glucose values of a user using the PPG sensor, displaying a notification prompting the user to measure blood glucose values using an external electronic device based at least partially on the monitored blood glucose values, and receive additional blood glucose values measured by the external electronic device using the wireless communication circuit.